STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANKRD36CAnkyrin repeat domain 36C. (1778 aa)    
Predicted Functional Partners:
ANKRD36
Ankyrin repeat domain-containing protein 36A; Ankyrin repeat domain 36.
  
  
0.999
ANKRD36B
Ankyrin repeat domain 36B; Belongs to the ANKRD36 family.
  
 
0.896
FAHD2B
Fumarylacetoacetate hydrolase domain-containing protein 2B; May have hydrolase activity.
   
  
 0.519
ZNF717
Zinc finger protein 717; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
    
 
 0.507
CDKN2D
Cyclin-dependent kinase 4 inhibitor D; Interacts strongly with CDK4 and CDK6 and inhibits them. Belongs to the CDKN2 cyclin-dependent kinase inhibitor family.
  
     0.501
CDKN2C
Cyclin-dependent kinase 4 inhibitor C; Interacts strongly with CDK6, weakly with CDK4. Inhibits cell growth and proliferation with a correlated dependence on endogenous retinoblastoma protein RB; Belongs to the CDKN2 cyclin-dependent kinase inhibitor family.
  
     0.482
FAM178B
Protein FAM178B; Family with sequence similarity 178 member B.
      
 0.480
LOC112267897
Uncharacterized protein.
    
 
 0.476
FAM104B
Protein FAM104B; Family with sequence similarity 104 member B.
      
 0.471
ASB12
Ankyrin repeat and SOCS box protein 12; Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
  
    0.454
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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