node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ARMCX4 | CACHD1 | ENSP00000404304 | ENSP00000290039 | Armadillo repeat containing X-linked 4; Belongs to the eutherian X-chromosome-specific Armcx family. | VWFA and cache domain-containing protein 1; May regulate voltage-dependent calcium channels. | 0.506 |
ARMCX4 | DNAH14 | ENSP00000404304 | ENSP00000383737 | Armadillo repeat containing X-linked 4; Belongs to the eutherian X-chromosome-specific Armcx family. | Dynein axonemal heavy chain 14. | 0.543 |
ARMCX4 | DPAGT1 | ENSP00000404304 | ENSP00000386597 | Armadillo repeat containing X-linked 4; Belongs to the eutherian X-chromosome-specific Armcx family. | UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase; Catalyzes the initial step of dolichol-linked oligosaccharide biosynthesis in N-linked protein glycosylation pathway: transfers GlcNAc-1-P from UDP-GlcNAc onto the carrier lipid dolichyl phosphate (P-dolichol), yielding GlcNAc-P-P-dolichol. | 0.731 |
ARMCX4 | MFSD6L | ENSP00000404304 | ENSP00000330051 | Armadillo repeat containing X-linked 4; Belongs to the eutherian X-chromosome-specific Armcx family. | Major facilitator superfamily domain containing 6 like. | 0.560 |
ARMCX4 | NECAB3 | ENSP00000404304 | ENSP00000246190 | Armadillo repeat containing X-linked 4; Belongs to the eutherian X-chromosome-specific Armcx family. | N-terminal EF-hand calcium-binding protein 3; Inhibits the interaction of APBA2 with amyloid-beta precursor protein (APP), and hence allows formation of amyloid-beta. May enhance the activity of HIF1A and thus promote glycolysis under normoxic conditions; the function requires its ABM domain and may implicate the stabilization of the interaction between HIF1AN and APBA3. | 0.524 |
ARMCX4 | SH3RF2 | ENSP00000404304 | ENSP00000424497 | Armadillo repeat containing X-linked 4; Belongs to the eutherian X-chromosome-specific Armcx family. | E3 ubiquitin-protein ligase SH3RF2; Has E3 ubiquitin-protein ligase activity. Acts as an anti-apoptotic regulator of the JNK pathway by ubiquitinating and promoting the degradation of SH3RF1, a scaffold protein that is required for pro-apoptotic JNK activation. Facilitates TNF-alpha-mediated recruitment of adapter proteins TRADD and RIPK1 to TNFRSF1A and regulates PAK4 protein stability via inhibition of its ubiquitin-mediated proteasomal degradation. Inhibits PPP1CA phosphatase activity. | 0.510 |
ARMCX4 | TADA3 | ENSP00000404304 | ENSP00000307684 | Armadillo repeat containing X-linked 4; Belongs to the eutherian X-chromosome-specific Armcx family. | Transcriptional adapter 3; Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex. Also known as a coactivator for p53/TP53- dependent transcriptional activation. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. Belongs to the NGG1 family. | 0.521 |
ARMCX4 | TRAPPC12 | ENSP00000404304 | ENSP00000324318 | Armadillo repeat containing X-linked 4; Belongs to the eutherian X-chromosome-specific Armcx family. | Trafficking protein particle complex subunit 12; Component of the TRAPP complex, which is involved in endoplasmic reticulum to Golgi apparatus trafficking at a very early stage. Also plays a role in chromosome congression, kinetochore assembly and stability and controls the recruitment of CENPE to the kinetochores. | 0.492 |
ARMCX4 | ZNF605 | ENSP00000404304 | ENSP00000376135 | Armadillo repeat containing X-linked 4; Belongs to the eutherian X-chromosome-specific Armcx family. | Zinc finger protein 605; May be involved in transcriptional regulation. | 0.526 |
ARMCX4 | ZSCAN29 | ENSP00000404304 | ENSP00000380174 | Armadillo repeat containing X-linked 4; Belongs to the eutherian X-chromosome-specific Armcx family. | Zinc finger and SCAN domain-containing protein 29; May be involved in transcriptional regulation. | 0.486 |
CACHD1 | ARMCX4 | ENSP00000290039 | ENSP00000404304 | VWFA and cache domain-containing protein 1; May regulate voltage-dependent calcium channels. | Armadillo repeat containing X-linked 4; Belongs to the eutherian X-chromosome-specific Armcx family. | 0.506 |
CACHD1 | MFSD6L | ENSP00000290039 | ENSP00000330051 | VWFA and cache domain-containing protein 1; May regulate voltage-dependent calcium channels. | Major facilitator superfamily domain containing 6 like. | 0.538 |
CACHD1 | NECAB3 | ENSP00000290039 | ENSP00000246190 | VWFA and cache domain-containing protein 1; May regulate voltage-dependent calcium channels. | N-terminal EF-hand calcium-binding protein 3; Inhibits the interaction of APBA2 with amyloid-beta precursor protein (APP), and hence allows formation of amyloid-beta. May enhance the activity of HIF1A and thus promote glycolysis under normoxic conditions; the function requires its ABM domain and may implicate the stabilization of the interaction between HIF1AN and APBA3. | 0.478 |
CACHD1 | TADA3 | ENSP00000290039 | ENSP00000307684 | VWFA and cache domain-containing protein 1; May regulate voltage-dependent calcium channels. | Transcriptional adapter 3; Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex. Also known as a coactivator for p53/TP53- dependent transcriptional activation. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. Belongs to the NGG1 family. | 0.417 |
DNAH14 | ARMCX4 | ENSP00000383737 | ENSP00000404304 | Dynein axonemal heavy chain 14. | Armadillo repeat containing X-linked 4; Belongs to the eutherian X-chromosome-specific Armcx family. | 0.543 |
DNAH14 | ZNF605 | ENSP00000383737 | ENSP00000376135 | Dynein axonemal heavy chain 14. | Zinc finger protein 605; May be involved in transcriptional regulation. | 0.435 |
DNAH14 | ZSCAN29 | ENSP00000383737 | ENSP00000380174 | Dynein axonemal heavy chain 14. | Zinc finger and SCAN domain-containing protein 29; May be involved in transcriptional regulation. | 0.418 |
DPAGT1 | ARMCX4 | ENSP00000386597 | ENSP00000404304 | UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase; Catalyzes the initial step of dolichol-linked oligosaccharide biosynthesis in N-linked protein glycosylation pathway: transfers GlcNAc-1-P from UDP-GlcNAc onto the carrier lipid dolichyl phosphate (P-dolichol), yielding GlcNAc-P-P-dolichol. | Armadillo repeat containing X-linked 4; Belongs to the eutherian X-chromosome-specific Armcx family. | 0.731 |
MFSD6L | ARMCX4 | ENSP00000330051 | ENSP00000404304 | Major facilitator superfamily domain containing 6 like. | Armadillo repeat containing X-linked 4; Belongs to the eutherian X-chromosome-specific Armcx family. | 0.560 |
MFSD6L | CACHD1 | ENSP00000330051 | ENSP00000290039 | Major facilitator superfamily domain containing 6 like. | VWFA and cache domain-containing protein 1; May regulate voltage-dependent calcium channels. | 0.538 |