STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FAM86B1Putative protein N-methyltransferase FAM86B1; Family with sequence similarity 86 member B1. (296 aa)    
Predicted Functional Partners:
DEFB135
Beta-defensin 135; Has antibacterial activity; Belongs to the beta-defensin family.
      
 0.577
DEFB134
Beta-defensin 134; Has antibacterial activity; Belongs to the beta-defensin family.
      
 0.577
KRBA2
KRAB-A domain containing 2.
   
  
 0.511
CCDC9B
Coiled-coil domain containing 9B.
      
 0.507
TMEM44
Transmembrane protein 44.
   
  
 0.484
KRBA1
Protein KRBA1; KRAB-A domain containing 1.
   
  
 0.480
SERGEF
Secretion-regulating guanine nucleotide exchange factor; Probable guanine nucleotide exchange factor (GEF), which may be involved in the secretion process.
   
  
 0.451
FAM86C1
Protein FAM86C1.
   
 
0.435
TMEM120B
Transmembrane protein 120B; Necessary for efficient adipogenesis. Belongs to the TMEM120 family.
      
 0.418
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.