STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IQCA1Iq and aaa domain-containing protein 1; IQ motif containing with AAA domain 1 (830 aa)    
Predicted Functional Partners:
CFAP58
Cilia- and flagella-associated protein 58; Cilia and flagella associated protein 58; Belongs to the CFAP58 family
   
  
 0.802
IQCD
IQ domain-containing protein D; Cilia and flagella associated
   
  
 0.787
CYB5D1
Cytochrome b5 domain-containing protein 1; Cytochrome b5 domain containing 1
   
 
 0.782
EFCAB2
EF-hand calcium-binding domain-containing protein 2; EF-hand calcium binding domain 2; Cilia and flagella associated
    
 
 0.782
CFAP20
Cilia- and flagella-associated protein 20; Cilium- and flagellum-specific protein that plays a role in axonemal structure organization and motility. Involved in the regulation of the size and morphology of cilia. Required for axonemal microtubules polyglutamylation
   
  
 0.738
TCTE1
T-complex-associated testis-expressed protein 1; T-complex-associated-testis-expressed 1; Dynein regulatory complex
    
 
 0.718
GAS8
Growth arrest-specific protein 8; Cytoskeletal linker which binds microtubules and probably functions in axonemal and non-axonemal dynein regulation. May play a role in the spermatozoa motility (By similarity). May play a role in cilia motility; Dynein regulatory complex
   
  
 0.717
CCDC135
Dynein regulatory complex subunit 7; Key component of the nexin-dynein regulatory complex (N- DRC), essential for N-DRC integrity. Involved in the regulation of flagellar motility; Belongs to the DRC7 family
      
 0.695
ARL14
ADP-ribosylation factor-like protein 14; GTPase that recruits MYO1E to MHC class II-containing vesicles via the effector protein ARL14EP and hence controls the movement of these vesicles along the actin cytoskeleton in dendritic cells; ARF GTPase family
    
 
 0.694
CFAP61
Cilia- and flagella-associated protein 61; May regulate cilium motility through its role in the assembly of the axonemal radial spokes; Cilia and flagella associated
   
  
 0.647
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
Server load: low (6%) [HD]