node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
JCAD | ZNF799 | ENSP00000364526 | ENSP00000411084 | Junctional protein associated with coronary artery disease; Junctional cadherin 5 associated. | Zinc finger protein 799; May be involved in transcriptional regulation. | 0.439 |
KHDC1 | ZNF799 | ENSP00000359411 | ENSP00000411084 | KH homology domain-containing protein 1; KH domain containing 1; Belongs to the KHDC1 family. | Zinc finger protein 799; May be involved in transcriptional regulation. | 0.476 |
SDK2 | ZNF799 | ENSP00000376421 | ENSP00000411084 | Protein sidekick-2; Adhesion molecule that promotes lamina-specific synaptic connections in the retina and is specifically required for the formation of neuronal circuits that detect motion. Acts by promoting formation of synapses between two specific retinal cell types: the retinal ganglion cells W3B-RGCs and the excitatory amacrine cells VG3- ACs. Formation of synapses between these two cells plays a key role in detection of motion. Promotes synaptic connectivity via homophilic interactions. | Zinc finger protein 799; May be involved in transcriptional regulation. | 0.418 |
SERPINB11 | ZNF799 | ENSP00000485532 | ENSP00000411084 | Serpin B11; Has no serine protease inhibitory activity, probably due to mutations in the scaffold impairing conformational change. | Zinc finger protein 799; May be involved in transcriptional regulation. | 0.479 |
TAS2R46 | ZNF799 | ENSP00000436450 | ENSP00000411084 | Taste receptor type 2 member 46; Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity). In airway epithelial cells, binding of bitter compounds increases the intracellular calcium ion concentration and stimulates ciliary beat frequency (By similarity); Belongs to the G-protein coupled receptor T2R family. | Zinc finger protein 799; May be involved in transcriptional regulation. | 0.479 |
TRIM28 | ZNF235 | ENSP00000253024 | ENSP00000291182 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 235; May be involved in transcriptional regulation. | 0.679 |
TRIM28 | ZNF564 | ENSP00000253024 | ENSP00000340004 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 564; May be involved in transcriptional regulation. | 0.580 |
TRIM28 | ZNF613 | ENSP00000253024 | ENSP00000293471 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 613; May be involved in transcriptional regulation. | 0.522 |
TRIM28 | ZNF799 | ENSP00000253024 | ENSP00000411084 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 799; May be involved in transcriptional regulation. | 0.585 |
ZNF235 | TRIM28 | ENSP00000291182 | ENSP00000253024 | Zinc finger protein 235; May be involved in transcriptional regulation. | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | 0.679 |
ZNF235 | ZNF799 | ENSP00000291182 | ENSP00000411084 | Zinc finger protein 235; May be involved in transcriptional regulation. | Zinc finger protein 799; May be involved in transcriptional regulation. | 0.640 |
ZNF564 | TRIM28 | ENSP00000340004 | ENSP00000253024 | Zinc finger protein 564; May be involved in transcriptional regulation. | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | 0.580 |
ZNF564 | ZNF799 | ENSP00000340004 | ENSP00000411084 | Zinc finger protein 564; May be involved in transcriptional regulation. | Zinc finger protein 799; May be involved in transcriptional regulation. | 0.460 |
ZNF613 | TRIM28 | ENSP00000293471 | ENSP00000253024 | Zinc finger protein 613; May be involved in transcriptional regulation. | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | 0.522 |
ZNF613 | ZNF799 | ENSP00000293471 | ENSP00000411084 | Zinc finger protein 613; May be involved in transcriptional regulation. | Zinc finger protein 799; May be involved in transcriptional regulation. | 0.780 |
ZNF613 | ZNF816 | ENSP00000293471 | ENSP00000350295 | Zinc finger protein 613; May be involved in transcriptional regulation. | Zinc finger protein 816; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.484 |
ZNF799 | JCAD | ENSP00000411084 | ENSP00000364526 | Zinc finger protein 799; May be involved in transcriptional regulation. | Junctional protein associated with coronary artery disease; Junctional cadherin 5 associated. | 0.439 |
ZNF799 | KHDC1 | ENSP00000411084 | ENSP00000359411 | Zinc finger protein 799; May be involved in transcriptional regulation. | KH homology domain-containing protein 1; KH domain containing 1; Belongs to the KHDC1 family. | 0.476 |
ZNF799 | SDK2 | ENSP00000411084 | ENSP00000376421 | Zinc finger protein 799; May be involved in transcriptional regulation. | Protein sidekick-2; Adhesion molecule that promotes lamina-specific synaptic connections in the retina and is specifically required for the formation of neuronal circuits that detect motion. Acts by promoting formation of synapses between two specific retinal cell types: the retinal ganglion cells W3B-RGCs and the excitatory amacrine cells VG3- ACs. Formation of synapses between these two cells plays a key role in detection of motion. Promotes synaptic connectivity via homophilic interactions. | 0.418 |
ZNF799 | SERPINB11 | ENSP00000411084 | ENSP00000485532 | Zinc finger protein 799; May be involved in transcriptional regulation. | Serpin B11; Has no serine protease inhibitory activity, probably due to mutations in the scaffold impairing conformational change. | 0.479 |