STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RPL1060S ribosomal protein L10; Component of the large ribosomal subunit. Plays a role in the formation of actively translating ribosomes. May play a role in the embryonic brain development (214 aa)    
Predicted Functional Partners:
RPL18A
Large subunit ribosomal protein l18ae; Belongs to the eukaryotic ribosomal protein eL20 family
   
 
 0.999
RPL19
Large subunit ribosomal protein l19e; Ribosomal protein L19; Belongs to the eukaryotic ribosomal protein eL19 family
   
 
 0.999
RPS12
Small subunit ribosomal protein s12e; Ribosomal protein S12
  
 
 0.999
RPS16
Small subunit ribosomal protein s16e; Ribosomal protein S16
  
 
 0.999
RPL35
60S ribosomal protein L35; Component of the large ribosomal subunit
  
 
 0.999
RPL8
60S ribosomal protein L8; Component of the large ribosomal subunit
  
 
 0.999
RPS11
Small subunit ribosomal protein s11e; Ribosomal protein S11; Belongs to the universal ribosomal protein uS17 family
 
 
 0.999
RPS3
40S ribosomal protein S3; Involved in translation as a component of the 40S small ribosomal subunit. Has endonuclease activity and plays a role in repair of damaged DNA. Cleaves phosphodiester bonds of DNAs containing altered bases with broad specificity and cleaves supercoiled DNA more efficiently than relaxed DNA. Displays high binding affinity for 7,8-dihydro-8-oxoguanine (8-oxoG), a common DNA lesion caused by reactive oxygen species (ROS). Has also been shown to bind with similar affinity to intact and damaged DNA. Stimulates the N-glycosylase activity of the base excision protein [...]
  
 
 0.999
RPS23
40S ribosomal protein S23; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...]
  
 
 0.999
RPS9
Small subunit ribosomal protein s9e; Ribosomal protein S9
 
 
 0.999
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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