node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANKRD20A2 | ANKRD20A4 | ENSP00000366826 | ENSP00000349891 | Ankyrin repeat domain-containing protein 20A2. | Ankyrin repeat domain-containing protein 20A4. | 0.631 |
ANKRD20A2 | ZNF492 | ENSP00000366826 | ENSP00000413660 | Ankyrin repeat domain-containing protein 20A2. | Zinc finger protein 492; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.504 |
ANKRD20A4 | ANKRD20A2 | ENSP00000349891 | ENSP00000366826 | Ankyrin repeat domain-containing protein 20A4. | Ankyrin repeat domain-containing protein 20A2. | 0.631 |
ANKRD20A4 | ZNF492 | ENSP00000349891 | ENSP00000413660 | Ankyrin repeat domain-containing protein 20A4. | Zinc finger protein 492; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.503 |
GPR149 | ZNF492 | ENSP00000374390 | ENSP00000413660 | Probable G-protein coupled receptor 149; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. | Zinc finger protein 492; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.427 |
KRTAP19-2 | ZNF492 | ENSP00000335660 | ENSP00000413660 | Keratin-associated protein 19-2; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins; Belongs to the KRTAP type 19 family. | Zinc finger protein 492; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.447 |
SATL1 | ZNF492 | ENSP00000425421 | ENSP00000413660 | Spermidine/spermine N1-acetyl transferase like 1. | Zinc finger protein 492; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.439 |
TCEANC | ZNF492 | ENSP00000440038 | ENSP00000413660 | Transcription elongation factor A N-terminal and central domain containing. | Zinc finger protein 492; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.439 |
TRIM28 | ZNF492 | ENSP00000253024 | ENSP00000413660 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 492; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.607 |
TRIM28 | ZNF675 | ENSP00000253024 | ENSP00000352836 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 675; May be involved in transcriptional regulation. May play a role during osteoclast differentiation by modulating TRAF6 signaling activity. | 0.580 |
TRIM28 | ZNF726 | ENSP00000253024 | ENSP00000471516 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 726; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.583 |
TRIM28 | ZNF99 | ENSP00000253024 | ENSP00000472969 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 99; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.522 |
ZNF492 | ANKRD20A2 | ENSP00000413660 | ENSP00000366826 | Zinc finger protein 492; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | Ankyrin repeat domain-containing protein 20A2. | 0.504 |
ZNF492 | ANKRD20A4 | ENSP00000413660 | ENSP00000349891 | Zinc finger protein 492; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | Ankyrin repeat domain-containing protein 20A4. | 0.503 |
ZNF492 | GPR149 | ENSP00000413660 | ENSP00000374390 | Zinc finger protein 492; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | Probable G-protein coupled receptor 149; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. | 0.427 |
ZNF492 | KRTAP19-2 | ENSP00000413660 | ENSP00000335660 | Zinc finger protein 492; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | Keratin-associated protein 19-2; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins; Belongs to the KRTAP type 19 family. | 0.447 |
ZNF492 | SATL1 | ENSP00000413660 | ENSP00000425421 | Zinc finger protein 492; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | Spermidine/spermine N1-acetyl transferase like 1. | 0.439 |
ZNF492 | TCEANC | ENSP00000413660 | ENSP00000440038 | Zinc finger protein 492; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | Transcription elongation factor A N-terminal and central domain containing. | 0.439 |
ZNF492 | TRIM28 | ENSP00000413660 | ENSP00000253024 | Zinc finger protein 492; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | 0.607 |
ZNF492 | ZNF675 | ENSP00000413660 | ENSP00000352836 | Zinc finger protein 492; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | Zinc finger protein 675; May be involved in transcriptional regulation. May play a role during osteoclast differentiation by modulating TRAF6 signaling activity. | 0.639 |