| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| C6orf120 | FAM120B | ENSP00000346931 | ENSP00000440125 | UPF0669 protein C6orf120; May be involved in induction of apoptosis in CD4(+) T-cells, but not CD8(+) T-cells or hepatocytes. | Constitutive coactivator of peroxisome proliferator-activated receptor gamma; Functions as a transactivator of PPARG and ESR1. Functions in adipogenesis through PPARG activation (By similarity); Belongs to the constitutive coactivator of PPAR-gamma family. | 0.403 |
| C6orf120 | PHF10 | ENSP00000346931 | ENSP00000341805 | UPF0669 protein C6orf120; May be involved in induction of apoptosis in CD4(+) T-cells, but not CD8(+) T-cells or hepatocytes. | PHD finger protein 10; Involved in transcription activity regulation by chromatin remodeling. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and is required for the proliferation of neural progenitors. During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. [...] | 0.451 |
| C6orf120 | TCTE3 | ENSP00000346931 | ENSP00000355736 | UPF0669 protein C6orf120; May be involved in induction of apoptosis in CD4(+) T-cells, but not CD8(+) T-cells or hepatocytes. | Tctex1 domain-containing protein 3; May be an accessory component of axonemal dynein and cytoplasmic dynein 1. Candidate for involvement in male sterility (By similarity); Belongs to the dynein light chain Tctex-type family. | 0.579 |
| C6orf120 | WDR27 | ENSP00000346931 | ENSP00000416289 | UPF0669 protein C6orf120; May be involved in induction of apoptosis in CD4(+) T-cells, but not CD8(+) T-cells or hepatocytes. | WD repeat domain 27. | 0.610 |
| CD8B2 | WDR27 | ENSP00000496416 | ENSP00000416289 | T-cell surface glycoprotein CD8 beta-2 chain; Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing (By similarity). | WD repeat domain 27. | 0.527 |
| CXorf56 | HTR5A | ENSP00000441786 | ENSP00000287907 | UPF0428 protein CXorf56; Chromosome X open reading frame 56. | 5-hydroxytryptamine receptor 5A; This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins; Belongs to the G-protein coupled receptor 1 family. | 0.520 |
| CXorf56 | WDR27 | ENSP00000441786 | ENSP00000416289 | UPF0428 protein CXorf56; Chromosome X open reading frame 56. | WD repeat domain 27. | 0.645 |
| DACT2 | FRMD1 | ENSP00000355760 | ENSP00000283309 | Dapper homolog 2; Involved in regulation of intracellular signaling pathways during development. Negatively regulates the Nodal signaling pathway, possibly by promoting the lysosomal degradation of Nodal receptors, such as TGFBR1. May be involved in control of the morphogenetic behavior of kidney ureteric bud cells by keeping cells epithelial and restraining their mesenchymal character. May play an inhibitory role in the re-epithelialization of skin wounds by attenuating TGF-beta signaling (By similarity); Belongs to the dapper family. | FERM domain containing 1. | 0.565 |
| DACT2 | PHF10 | ENSP00000355760 | ENSP00000341805 | Dapper homolog 2; Involved in regulation of intracellular signaling pathways during development. Negatively regulates the Nodal signaling pathway, possibly by promoting the lysosomal degradation of Nodal receptors, such as TGFBR1. May be involved in control of the morphogenetic behavior of kidney ureteric bud cells by keeping cells epithelial and restraining their mesenchymal character. May play an inhibitory role in the re-epithelialization of skin wounds by attenuating TGF-beta signaling (By similarity); Belongs to the dapper family. | PHD finger protein 10; Involved in transcription activity regulation by chromatin remodeling. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and is required for the proliferation of neural progenitors. During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. [...] | 0.461 |
| DACT2 | SMOC2 | ENSP00000355760 | ENSP00000346537 | Dapper homolog 2; Involved in regulation of intracellular signaling pathways during development. Negatively regulates the Nodal signaling pathway, possibly by promoting the lysosomal degradation of Nodal receptors, such as TGFBR1. May be involved in control of the morphogenetic behavior of kidney ureteric bud cells by keeping cells epithelial and restraining their mesenchymal character. May play an inhibitory role in the re-epithelialization of skin wounds by attenuating TGF-beta signaling (By similarity); Belongs to the dapper family. | SPARC-related modular calcium-binding protein 2; Promotes matrix assembly and cell adhesiveness (By similarity). Can stimulate endothelial cell proliferation, migration, as well as angiogenesis. | 0.527 |
| DACT2 | TCTE3 | ENSP00000355760 | ENSP00000355736 | Dapper homolog 2; Involved in regulation of intracellular signaling pathways during development. Negatively regulates the Nodal signaling pathway, possibly by promoting the lysosomal degradation of Nodal receptors, such as TGFBR1. May be involved in control of the morphogenetic behavior of kidney ureteric bud cells by keeping cells epithelial and restraining their mesenchymal character. May play an inhibitory role in the re-epithelialization of skin wounds by attenuating TGF-beta signaling (By similarity); Belongs to the dapper family. | Tctex1 domain-containing protein 3; May be an accessory component of axonemal dynein and cytoplasmic dynein 1. Candidate for involvement in male sterility (By similarity); Belongs to the dynein light chain Tctex-type family. | 0.543 |
| DACT2 | WDR27 | ENSP00000355760 | ENSP00000416289 | Dapper homolog 2; Involved in regulation of intracellular signaling pathways during development. Negatively regulates the Nodal signaling pathway, possibly by promoting the lysosomal degradation of Nodal receptors, such as TGFBR1. May be involved in control of the morphogenetic behavior of kidney ureteric bud cells by keeping cells epithelial and restraining their mesenchymal character. May play an inhibitory role in the re-epithelialization of skin wounds by attenuating TGF-beta signaling (By similarity); Belongs to the dapper family. | WD repeat domain 27. | 0.516 |
| FAM120B | C6orf120 | ENSP00000440125 | ENSP00000346931 | Constitutive coactivator of peroxisome proliferator-activated receptor gamma; Functions as a transactivator of PPARG and ESR1. Functions in adipogenesis through PPARG activation (By similarity); Belongs to the constitutive coactivator of PPAR-gamma family. | UPF0669 protein C6orf120; May be involved in induction of apoptosis in CD4(+) T-cells, but not CD8(+) T-cells or hepatocytes. | 0.403 |
| FAM120B | PHF10 | ENSP00000440125 | ENSP00000341805 | Constitutive coactivator of peroxisome proliferator-activated receptor gamma; Functions as a transactivator of PPARG and ESR1. Functions in adipogenesis through PPARG activation (By similarity); Belongs to the constitutive coactivator of PPAR-gamma family. | PHD finger protein 10; Involved in transcription activity regulation by chromatin remodeling. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and is required for the proliferation of neural progenitors. During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. [...] | 0.431 |
| FAM120B | TCTE3 | ENSP00000440125 | ENSP00000355736 | Constitutive coactivator of peroxisome proliferator-activated receptor gamma; Functions as a transactivator of PPARG and ESR1. Functions in adipogenesis through PPARG activation (By similarity); Belongs to the constitutive coactivator of PPAR-gamma family. | Tctex1 domain-containing protein 3; May be an accessory component of axonemal dynein and cytoplasmic dynein 1. Candidate for involvement in male sterility (By similarity); Belongs to the dynein light chain Tctex-type family. | 0.436 |
| FAM120B | WDR27 | ENSP00000440125 | ENSP00000416289 | Constitutive coactivator of peroxisome proliferator-activated receptor gamma; Functions as a transactivator of PPARG and ESR1. Functions in adipogenesis through PPARG activation (By similarity); Belongs to the constitutive coactivator of PPAR-gamma family. | WD repeat domain 27. | 0.515 |
| FRMD1 | DACT2 | ENSP00000283309 | ENSP00000355760 | FERM domain containing 1. | Dapper homolog 2; Involved in regulation of intracellular signaling pathways during development. Negatively regulates the Nodal signaling pathway, possibly by promoting the lysosomal degradation of Nodal receptors, such as TGFBR1. May be involved in control of the morphogenetic behavior of kidney ureteric bud cells by keeping cells epithelial and restraining their mesenchymal character. May play an inhibitory role in the re-epithelialization of skin wounds by attenuating TGF-beta signaling (By similarity); Belongs to the dapper family. | 0.565 |
| FRMD1 | PHF10 | ENSP00000283309 | ENSP00000341805 | FERM domain containing 1. | PHD finger protein 10; Involved in transcription activity regulation by chromatin remodeling. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and is required for the proliferation of neural progenitors. During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. [...] | 0.479 |
| FRMD1 | SMOC2 | ENSP00000283309 | ENSP00000346537 | FERM domain containing 1. | SPARC-related modular calcium-binding protein 2; Promotes matrix assembly and cell adhesiveness (By similarity). Can stimulate endothelial cell proliferation, migration, as well as angiogenesis. | 0.501 |
| FRMD1 | TCTE3 | ENSP00000283309 | ENSP00000355736 | FERM domain containing 1. | Tctex1 domain-containing protein 3; May be an accessory component of axonemal dynein and cytoplasmic dynein 1. Candidate for involvement in male sterility (By similarity); Belongs to the dynein light chain Tctex-type family. | 0.578 |
STRING v12.5 is now available!
