STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C3orf14Uncharacterized protein C3orf14; Chromosome 3 open reading frame 14. (128 aa)    
Predicted Functional Partners:
CEP89
Centrosomal protein of 89 kDa; Required for ciliogenesis. Also plays a role in mitochondrial metabolism where it may modulate complex IV activity.
    
 
 0.766
C18orf54
Chromosome 18 open reading frame 54.
   
  
 0.591
CCDC77
Coiled-coil domain containing 77.
   
  
 0.560
CCDC150
Coiled-coil domain containing 150.
   
  
 0.559
RIBC2
RIB43A domain with coiled-coils 2.
      
 0.528
C9orf40
Uncharacterized protein C9orf40; Chromosome 9 open reading frame 40.
   
  
 0.510
DONSON
Protein downstream neighbor of Son; Replisome component that maintains genome stability by protecting stalled or damaged replication forks. After the induction of replication stress, required for the stabilization of stalled replication forks, the efficient activation of the intra-S-phase and G/2M cell-cycle checkpoints and the maintenance of genome stability.
   
  
 0.460
OTULINL
Inactive ubiquitin thioesterase OTULINL; Lacks deubiquitinase activity; Belongs to the peptidase C65 family. Otulin subfamily.
      
 0.459
ZNF367
Zinc finger protein 367; Transcriptional activator. Isoform 1 may be involved in transcriptional activation of erythroid genes.
   
  
 0.456
SATL1
Spermidine/spermine N1-acetyl transferase like 1.
      
 0.449
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.