RPL7L1 protein (human) - STRING interaction network

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[Homology]

Score

RPL7L1

Ribosomal protein L7 like 1. (255 aa)

Predicted Functional Partners:

PES1

0.999

NIFK

0.998

BOP1

0.998

NOP53

0.996

WDR12

0.996

RPL23A

0.996

RPL23

0.996

RPS13

0.996

RPL9

0.996

RPL35

0.995

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BOP1	NIFK	ENSP00000455106	ENSP00000285814	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the WD repeat BOP1/ERB1 family.	Nucleolar protein interacting with the FHA domain of MKI67.	0.996
BOP1	NOP53	ENSP00000455106	ENSP00000246802	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the WD repeat BOP1/ERB1 family.	Ribosome biogenesis protein NOP53; Nucleolar protein which is involved in the integration of the 5S RNP into the ribosomal large subunit during ribosome biogenesis. In ribosome biogenesis, may also play a role in rRNA transcription. Also functions as a nucleolar sensor that regulates the activation of p53/TP53 in response to ribosome biogenesis perturbation, DNA damage and other stress conditions. DNA damage or perturbation of ribosome biogenesis disrupt the interaction between NOP53 and RPL11 allowing RPL11 transport to the nucleoplasm where it can inhibit MDM2 and allow p53/TP53 acti [...]	0.683
BOP1	PES1	ENSP00000455106	ENSP00000346725	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the WD repeat BOP1/ERB1 family.	Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. Belongs to the pescadillo family.	0.999
BOP1	RPL23	ENSP00000455106	ENSP00000420311	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the WD repeat BOP1/ERB1 family.	Ribosomal protein L23.	0.984
BOP1	RPL23A	ENSP00000455106	ENSP00000389103	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the WD repeat BOP1/ERB1 family.	60S ribosomal protein L23a; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Binds a specific region on the 26S rRNA. May promote p53/TP53 degradation possibly through the stimulation of MDM2-mediated TP53 polyubiquitination ; Belongs to the universal ribosomal protein uL23 family.	0.987
BOP1	RPL35	ENSP00000455106	ENSP00000259469	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the WD repeat BOP1/ERB1 family.	60S ribosomal protein L35; Component of the large ribosomal subunit.	0.979
BOP1	RPL7L1	ENSP00000455106	ENSP00000418221	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the WD repeat BOP1/ERB1 family.	Ribosomal protein L7 like 1.	0.998
BOP1	RPL9	ENSP00000455106	ENSP00000494697	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the WD repeat BOP1/ERB1 family.	Ribosomal protein L9.	0.983
BOP1	WDR12	ENSP00000455106	ENSP00000261015	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the WD repeat BOP1/ERB1 family.	Ribosome biogenesis protein WDR12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	0.999
NIFK	BOP1	ENSP00000285814	ENSP00000455106	Nucleolar protein interacting with the FHA domain of MKI67.	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the WD repeat BOP1/ERB1 family.	0.996
NIFK	NOP53	ENSP00000285814	ENSP00000246802	Nucleolar protein interacting with the FHA domain of MKI67.	Ribosome biogenesis protein NOP53; Nucleolar protein which is involved in the integration of the 5S RNP into the ribosomal large subunit during ribosome biogenesis. In ribosome biogenesis, may also play a role in rRNA transcription. Also functions as a nucleolar sensor that regulates the activation of p53/TP53 in response to ribosome biogenesis perturbation, DNA damage and other stress conditions. DNA damage or perturbation of ribosome biogenesis disrupt the interaction between NOP53 and RPL11 allowing RPL11 transport to the nucleoplasm where it can inhibit MDM2 and allow p53/TP53 acti [...]	0.997
NIFK	PES1	ENSP00000285814	ENSP00000346725	Nucleolar protein interacting with the FHA domain of MKI67.	Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. Belongs to the pescadillo family.	0.998
NIFK	RPL23	ENSP00000285814	ENSP00000420311	Nucleolar protein interacting with the FHA domain of MKI67.	Ribosomal protein L23.	0.975
NIFK	RPL23A	ENSP00000285814	ENSP00000389103	Nucleolar protein interacting with the FHA domain of MKI67.	60S ribosomal protein L23a; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Binds a specific region on the 26S rRNA. May promote p53/TP53 degradation possibly through the stimulation of MDM2-mediated TP53 polyubiquitination ; Belongs to the universal ribosomal protein uL23 family.	0.977
NIFK	RPL35	ENSP00000285814	ENSP00000259469	Nucleolar protein interacting with the FHA domain of MKI67.	60S ribosomal protein L35; Component of the large ribosomal subunit.	0.963
NIFK	RPL7L1	ENSP00000285814	ENSP00000418221	Nucleolar protein interacting with the FHA domain of MKI67.	Ribosomal protein L7 like 1.	0.998
NIFK	RPL9	ENSP00000285814	ENSP00000494697	Nucleolar protein interacting with the FHA domain of MKI67.	Ribosomal protein L9.	0.971
NIFK	RPS13	ENSP00000285814	ENSP00000435777	Nucleolar protein interacting with the FHA domain of MKI67.	Ribosomal protein S13.	0.460
NIFK	WDR12	ENSP00000285814	ENSP00000261015	Nucleolar protein interacting with the FHA domain of MKI67.	Ribosome biogenesis protein WDR12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.	0.998
NOP53	BOP1	ENSP00000246802	ENSP00000455106	Ribosome biogenesis protein NOP53; Nucleolar protein which is involved in the integration of the 5S RNP into the ribosomal large subunit during ribosome biogenesis. In ribosome biogenesis, may also play a role in rRNA transcription. Also functions as a nucleolar sensor that regulates the activation of p53/TP53 in response to ribosome biogenesis perturbation, DNA damage and other stress conditions. DNA damage or perturbation of ribosome biogenesis disrupt the interaction between NOP53 and RPL11 allowing RPL11 transport to the nucleoplasm where it can inhibit MDM2 and allow p53/TP53 acti [...]	Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the WD repeat BOP1/ERB1 family.	0.683