EFCAB10 protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AK8	C20orf85	ENSP00000298545	ENSP00000360210	Adenylate kinase 8; Nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP. Also displays broad nucleoside diphosphate kinase activity.	Uncharacterized protein C20orf85; Chromosome 20 open reading frame 85.	0.632
AK8	EFCAB1	ENSP00000298545	ENSP00000262103	Adenylate kinase 8; Nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP. Also displays broad nucleoside diphosphate kinase activity.	EF-hand calcium-binding domain-containing protein 1; EF-hand calcium binding domain 1.	0.635
AK8	EFCAB10	ENSP00000298545	ENSP00000417841	Adenylate kinase 8; Nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP. Also displays broad nucleoside diphosphate kinase activity.	EF-hand calcium-binding domain-containing protein 10; EF-hand calcium binding domain 10.	0.734
AK8	EFCAB3	ENSP00000298545	ENSP00000403932	Adenylate kinase 8; Nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP. Also displays broad nucleoside diphosphate kinase activity.	EF-hand calcium-binding domain-containing protein 3; EF-hand calcium binding domain 3.	0.740
AK8	EFHB	ENSP00000298545	ENSP00000295824	Adenylate kinase 8; Nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP. Also displays broad nucleoside diphosphate kinase activity.	EF-hand domain-containing family member B; Cytosolic sensor for calcium, modulates the interaction of STIM1 and ORAI1 upon store depletion, the activation of store-operated Ca(2+) entry (SOCE) and NFAT translocation from cytosol to nucleus.	0.858
AK8	EFHC2	ENSP00000298545	ENSP00000404232	Adenylate kinase 8; Nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP. Also displays broad nucleoside diphosphate kinase activity.	EF-hand domain-containing family member C2; EF-hand domain containing 2.	0.852
AK8	FAM183A	ENSP00000298545	ENSP00000334415	Adenylate kinase 8; Nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP. Also displays broad nucleoside diphosphate kinase activity.	Protein FAM183A; Family with sequence similarity 183 member A; Belongs to the FAM183 family.	0.635
AK8	MORN5	ENSP00000298545	ENSP00000362869	Adenylate kinase 8; Nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP. Also displays broad nucleoside diphosphate kinase activity.	MORN repeat containing 5.	0.683
AK8	SPA17	ENSP00000298545	ENSP00000432305	Adenylate kinase 8; Nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP. Also displays broad nucleoside diphosphate kinase activity.	Sperm surface protein Sp17; Sperm surface zona pellucida binding protein. Helps to bind spermatozoa to the zona pellucida with high affinity. Might function in binding zona pellucida and carbohydrates (By similarity).	0.738
AK8	TEKT1	ENSP00000298545	ENSP00000341346	Adenylate kinase 8; Nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP. Also displays broad nucleoside diphosphate kinase activity.	Tektin-1; Structural component of ciliary and flagellar microtubules. Forms filamentous polymers in the walls of ciliary and flagellar microtubules; Belongs to the tektin family.	0.740
C20orf85	AK8	ENSP00000360210	ENSP00000298545	Uncharacterized protein C20orf85; Chromosome 20 open reading frame 85.	Adenylate kinase 8; Nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP. Also displays broad nucleoside diphosphate kinase activity.	0.632
C20orf85	EFCAB1	ENSP00000360210	ENSP00000262103	Uncharacterized protein C20orf85; Chromosome 20 open reading frame 85.	EF-hand calcium-binding domain-containing protein 1; EF-hand calcium binding domain 1.	0.692
C20orf85	EFCAB10	ENSP00000360210	ENSP00000417841	Uncharacterized protein C20orf85; Chromosome 20 open reading frame 85.	EF-hand calcium-binding domain-containing protein 10; EF-hand calcium binding domain 10.	0.821
C20orf85	EFCAB3	ENSP00000360210	ENSP00000403932	Uncharacterized protein C20orf85; Chromosome 20 open reading frame 85.	EF-hand calcium-binding domain-containing protein 3; EF-hand calcium binding domain 3.	0.817
C20orf85	EFHB	ENSP00000360210	ENSP00000295824	Uncharacterized protein C20orf85; Chromosome 20 open reading frame 85.	EF-hand domain-containing family member B; Cytosolic sensor for calcium, modulates the interaction of STIM1 and ORAI1 upon store depletion, the activation of store-operated Ca(2+) entry (SOCE) and NFAT translocation from cytosol to nucleus.	0.854
C20orf85	EFHC2	ENSP00000360210	ENSP00000404232	Uncharacterized protein C20orf85; Chromosome 20 open reading frame 85.	EF-hand domain-containing family member C2; EF-hand domain containing 2.	0.817
C20orf85	FAM183A	ENSP00000360210	ENSP00000334415	Uncharacterized protein C20orf85; Chromosome 20 open reading frame 85.	Protein FAM183A; Family with sequence similarity 183 member A; Belongs to the FAM183 family.	0.902
C20orf85	MORN5	ENSP00000360210	ENSP00000362869	Uncharacterized protein C20orf85; Chromosome 20 open reading frame 85.	MORN repeat containing 5.	0.811
C20orf85	SPA17	ENSP00000360210	ENSP00000432305	Uncharacterized protein C20orf85; Chromosome 20 open reading frame 85.	Sperm surface protein Sp17; Sperm surface zona pellucida binding protein. Helps to bind spermatozoa to the zona pellucida with high affinity. Might function in binding zona pellucida and carbohydrates (By similarity).	0.702
C20orf85	TEKT1	ENSP00000360210	ENSP00000341346	Uncharacterized protein C20orf85; Chromosome 20 open reading frame 85.	Tektin-1; Structural component of ciliary and flagellar microtubules. Forms filamentous polymers in the walls of ciliary and flagellar microtubules; Belongs to the tektin family.	0.911