node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
COLGALT2 | RWDD2B | ENSP00000354960 | ENSP00000418693 | Procollagen galactosyltransferase 2; Beta-galactosyltransferase that transfers beta-galactose to hydroxylysine residues of collagen; Belongs to the glycosyltransferase 25 family. | RWD domain containing 2B. | 0.486 |
FAM24B | RWDD2B | ENSP00000357894 | ENSP00000418693 | Protein FAM24B; Family with sequence similarity 24 member B. | RWD domain containing 2B. | 0.570 |
GADD45G | RWDD2B | ENSP00000252506 | ENSP00000418693 | Growth arrest and DNA damage-inducible protein GADD45 gamma; Involved in the regulation of growth and apoptosis. Mediates activation of stress-responsive MTK1/MEKK4 MAPKKK; Belongs to the GADD45 family. | RWD domain containing 2B. | 0.864 |
KLRG2 | RWDD2B | ENSP00000339356 | ENSP00000418693 | Killer cell lectin like receptor G2. | RWD domain containing 2B. | 0.463 |
LTN1 | RWDD2B | ENSP00000478783 | ENSP00000418693 | E3 ubiquitin-protein ligase listerin; E3 ubiquitin-protein ligase component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation. Ubiquitination leads to VCP/p97 recruitment for extraction and degradation of the incomplete translation product (By similarity). | RWD domain containing 2B. | 0.528 |
MAP3K7CL | RWDD2B | ENSP00000382828 | ENSP00000418693 | MAP3K7 C-terminal-like protein; MAP3K7 C-terminal like. | RWD domain containing 2B. | 0.471 |
PDLIM5 | RWDD2B | ENSP00000480359 | ENSP00000418693 | PDZ and LIM domain 5. | RWD domain containing 2B. | 0.622 |
POFUT2 | RWDD2B | ENSP00000339613 | ENSP00000418693 | GDP-fucose protein O-fucosyltransferase 2; Catalyzes the reaction that attaches fucose through an O- glycosidic linkage to a conserved serine or threonine residue in the consensus sequence C1-X(2,3)-S/T-C2-X(2)-G of thrombospondin type 1 repeats where C1 and C2 are the first and second cysteines, respectively. O-fucosylates members of several protein families including the ADAMTS family, the thrombosporin (TSP) and spondin families. The O-fucosylation of TSRs is also required for restricting epithelial to mesenchymal transition (EMT), maintaining the correct patterning of mesoderm and [...] | RWD domain containing 2B. | 0.571 |
POFUT2 | YBEY | ENSP00000339613 | ENSP00000329614 | GDP-fucose protein O-fucosyltransferase 2; Catalyzes the reaction that attaches fucose through an O- glycosidic linkage to a conserved serine or threonine residue in the consensus sequence C1-X(2,3)-S/T-C2-X(2)-G of thrombospondin type 1 repeats where C1 and C2 are the first and second cysteines, respectively. O-fucosylates members of several protein families including the ADAMTS family, the thrombosporin (TSP) and spondin families. The O-fucosylation of TSRs is also required for restricting epithelial to mesenchymal transition (EMT), maintaining the correct patterning of mesoderm and [...] | Endoribonuclease YbeY; Single strand-specific metallo-endoribonuclease involved in rRNA maturation. | 0.774 |
RWDD2B | COLGALT2 | ENSP00000418693 | ENSP00000354960 | RWD domain containing 2B. | Procollagen galactosyltransferase 2; Beta-galactosyltransferase that transfers beta-galactose to hydroxylysine residues of collagen; Belongs to the glycosyltransferase 25 family. | 0.486 |
RWDD2B | FAM24B | ENSP00000418693 | ENSP00000357894 | RWD domain containing 2B. | Protein FAM24B; Family with sequence similarity 24 member B. | 0.570 |
RWDD2B | GADD45G | ENSP00000418693 | ENSP00000252506 | RWD domain containing 2B. | Growth arrest and DNA damage-inducible protein GADD45 gamma; Involved in the regulation of growth and apoptosis. Mediates activation of stress-responsive MTK1/MEKK4 MAPKKK; Belongs to the GADD45 family. | 0.864 |
RWDD2B | KLRG2 | ENSP00000418693 | ENSP00000339356 | RWD domain containing 2B. | Killer cell lectin like receptor G2. | 0.463 |
RWDD2B | LTN1 | ENSP00000418693 | ENSP00000478783 | RWD domain containing 2B. | E3 ubiquitin-protein ligase listerin; E3 ubiquitin-protein ligase component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation. Ubiquitination leads to VCP/p97 recruitment for extraction and degradation of the incomplete translation product (By similarity). | 0.528 |
RWDD2B | MAP3K7CL | ENSP00000418693 | ENSP00000382828 | RWD domain containing 2B. | MAP3K7 C-terminal-like protein; MAP3K7 C-terminal like. | 0.471 |
RWDD2B | PDLIM5 | ENSP00000418693 | ENSP00000480359 | RWD domain containing 2B. | PDZ and LIM domain 5. | 0.622 |
RWDD2B | POFUT2 | ENSP00000418693 | ENSP00000339613 | RWD domain containing 2B. | GDP-fucose protein O-fucosyltransferase 2; Catalyzes the reaction that attaches fucose through an O- glycosidic linkage to a conserved serine or threonine residue in the consensus sequence C1-X(2,3)-S/T-C2-X(2)-G of thrombospondin type 1 repeats where C1 and C2 are the first and second cysteines, respectively. O-fucosylates members of several protein families including the ADAMTS family, the thrombosporin (TSP) and spondin families. The O-fucosylation of TSRs is also required for restricting epithelial to mesenchymal transition (EMT), maintaining the correct patterning of mesoderm and [...] | 0.571 |
RWDD2B | USP16 | ENSP00000418693 | ENSP00000334808 | RWD domain containing 2B. | Ubiquitin carboxyl-terminal hydrolase 16; Specifically deubiquitinates 'Lys-120' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A is a prerequisite for subsequent phosphorylation at 'Ser-11' of histone H3 (H3S10ph), and is required for chromosome segregation when cells enter into mitosis. In resting B- and T-lymphocytes, phosphorylation by AURKB leads to enhance its activity, thereby maintaining transcription in resting lymphocytes. Regulates Hox gene expression via histone H2A deubiqu [...] | 0.470 |
RWDD2B | YBEY | ENSP00000418693 | ENSP00000329614 | RWD domain containing 2B. | Endoribonuclease YbeY; Single strand-specific metallo-endoribonuclease involved in rRNA maturation. | 0.631 |
USP16 | RWDD2B | ENSP00000334808 | ENSP00000418693 | Ubiquitin carboxyl-terminal hydrolase 16; Specifically deubiquitinates 'Lys-120' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A is a prerequisite for subsequent phosphorylation at 'Ser-11' of histone H3 (H3S10ph), and is required for chromosome segregation when cells enter into mitosis. In resting B- and T-lymphocytes, phosphorylation by AURKB leads to enhance its activity, thereby maintaining transcription in resting lymphocytes. Regulates Hox gene expression via histone H2A deubiqu [...] | RWD domain containing 2B. | 0.470 |