ENSP00000418875 protein (human) - STRING interaction network

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Score

ENSP00000418875

Probable threonine protease PRSS50. (385 aa)

Predicted Functional Partners:

PRSS50

0.978

ADAM30

0.473

MYOZ3

0.446

ARMS2

0.441

THEGL

0.420

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADAM30	ENSP00000418875	ENSP00000358407	ENSP00000418875	Disintegrin and metalloproteinase domain-containing protein 30; Plays a role in lysosomal amyloid precursor protein (APP) processing by cleaving and activating CTSD/cathepsin D which leads to APP degradation.	Probable threonine protease PRSS50.	0.473
ADAM30	MYOZ3	ENSP00000358407	ENSP00000297130	Disintegrin and metalloproteinase domain-containing protein 30; Plays a role in lysosomal amyloid precursor protein (APP) processing by cleaving and activating CTSD/cathepsin D which leads to APP degradation.	Myozenin-3; Myozenins may serve as intracellular binding proteins involved in linking Z line proteins such as alpha-actinin, gamma- filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin signaling to the sarcomere. Plays an important role in the modulation of calcineurin signaling. May play a role in myofibrillogenesis.	0.405
ADAM30	PRSS50	ENSP00000358407	ENSP00000326598	Disintegrin and metalloproteinase domain-containing protein 30; Plays a role in lysosomal amyloid precursor protein (APP) processing by cleaving and activating CTSD/cathepsin D which leads to APP degradation.	Probable threonine protease PRSS50; May be involved in proteolysis through its threonine endopeptidase activity; Belongs to the peptidase S1 family.	0.457
ARMS2	ENSP00000418875	ENSP00000436682	ENSP00000418875	Age-related maculopathy susceptibility 2.	Probable threonine protease PRSS50.	0.441
ENSP00000418875	ADAM30	ENSP00000418875	ENSP00000358407	Probable threonine protease PRSS50.	Disintegrin and metalloproteinase domain-containing protein 30; Plays a role in lysosomal amyloid precursor protein (APP) processing by cleaving and activating CTSD/cathepsin D which leads to APP degradation.	0.473
ENSP00000418875	ARMS2	ENSP00000418875	ENSP00000436682	Probable threonine protease PRSS50.	Age-related maculopathy susceptibility 2.	0.441
ENSP00000418875	MYOZ3	ENSP00000418875	ENSP00000297130	Probable threonine protease PRSS50.	Myozenin-3; Myozenins may serve as intracellular binding proteins involved in linking Z line proteins such as alpha-actinin, gamma- filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin signaling to the sarcomere. Plays an important role in the modulation of calcineurin signaling. May play a role in myofibrillogenesis.	0.446
ENSP00000418875	PRSS50	ENSP00000418875	ENSP00000326598	Probable threonine protease PRSS50.	Probable threonine protease PRSS50; May be involved in proteolysis through its threonine endopeptidase activity; Belongs to the peptidase S1 family.	0.978
ENSP00000418875	THEGL	ENSP00000418875	ENSP00000456850	Probable threonine protease PRSS50.	Testicular haploid expressed gene protein-like; Theg spermatid protein like.	0.420
MYOZ3	ADAM30	ENSP00000297130	ENSP00000358407	Myozenin-3; Myozenins may serve as intracellular binding proteins involved in linking Z line proteins such as alpha-actinin, gamma- filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin signaling to the sarcomere. Plays an important role in the modulation of calcineurin signaling. May play a role in myofibrillogenesis.	Disintegrin and metalloproteinase domain-containing protein 30; Plays a role in lysosomal amyloid precursor protein (APP) processing by cleaving and activating CTSD/cathepsin D which leads to APP degradation.	0.405
MYOZ3	ENSP00000418875	ENSP00000297130	ENSP00000418875	Myozenin-3; Myozenins may serve as intracellular binding proteins involved in linking Z line proteins such as alpha-actinin, gamma- filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin signaling to the sarcomere. Plays an important role in the modulation of calcineurin signaling. May play a role in myofibrillogenesis.	Probable threonine protease PRSS50.	0.446
MYOZ3	PRSS50	ENSP00000297130	ENSP00000326598	Myozenin-3; Myozenins may serve as intracellular binding proteins involved in linking Z line proteins such as alpha-actinin, gamma- filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin signaling to the sarcomere. Plays an important role in the modulation of calcineurin signaling. May play a role in myofibrillogenesis.	Probable threonine protease PRSS50; May be involved in proteolysis through its threonine endopeptidase activity; Belongs to the peptidase S1 family.	0.433
PRSS50	ADAM30	ENSP00000326598	ENSP00000358407	Probable threonine protease PRSS50; May be involved in proteolysis through its threonine endopeptidase activity; Belongs to the peptidase S1 family.	Disintegrin and metalloproteinase domain-containing protein 30; Plays a role in lysosomal amyloid precursor protein (APP) processing by cleaving and activating CTSD/cathepsin D which leads to APP degradation.	0.457
PRSS50	ENSP00000418875	ENSP00000326598	ENSP00000418875	Probable threonine protease PRSS50; May be involved in proteolysis through its threonine endopeptidase activity; Belongs to the peptidase S1 family.	Probable threonine protease PRSS50.	0.978
PRSS50	MYOZ3	ENSP00000326598	ENSP00000297130	Probable threonine protease PRSS50; May be involved in proteolysis through its threonine endopeptidase activity; Belongs to the peptidase S1 family.	Myozenin-3; Myozenins may serve as intracellular binding proteins involved in linking Z line proteins such as alpha-actinin, gamma- filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin signaling to the sarcomere. Plays an important role in the modulation of calcineurin signaling. May play a role in myofibrillogenesis.	0.433
THEGL	ENSP00000418875	ENSP00000456850	ENSP00000418875	Testicular haploid expressed gene protein-like; Theg spermatid protein like.	Probable threonine protease PRSS50.	0.420