STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPATA45Spermatogenesis-associated protein 45; Spermatogenesis associated 45; Belongs to the SPATA45 family. (98 aa)    
Predicted Functional Partners:
TEX43
Testis-expressed protein 43; Testis expressed 43.
   
  
 0.683
TEX35
Testis-expressed protein 35; Testis expressed 35.
   
  
 0.664
SPATA18
Mitochondria-eating protein; Key regulator of mitochondrial quality that mediates the repairing or degradation of unhealthy mitochondria in response to mitochondrial damage. Mediator of mitochondrial protein catabolic process (also named MALM) by mediating the degradation of damaged proteins inside mitochondria by promoting the accumulation in the mitochondrial matrix of hydrolases that are characteristic of the lysosomal lumen. Also involved in mitochondrion degradation of damaged mitochondria by promoting the formation of vacuole-like structures (named MIV), which engulf and degrade [...]
      
 0.626
OR6K3
Olfactory receptor 6K3; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
      
 0.580
SPEM1
Spermatid maturation protein 1; Required for proper cytoplasm removal during spermatogenesis.
   
  
 0.541
CBY2
Chibby family member 2.
   
  
 0.527
SPATC1
Speriolin; Spermatogenesis and centriole associated 1; Belongs to the speriolin family.
   
  
 0.523
SPATA3
Spermatogenesis-associated protein 3; Spermatogenesis associated 3.
   
  
 0.523
LENEP
Lens epithelial cell protein LEP503; May play a role in lens epithelial cell differentiation.
   
  
 0.475
SPATA19
Spermatogenesis-associated protein 19, mitochondrial; May have a role in spermiogenesis.
   
  
 0.464
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.