node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AMMECR1 | FAM122B | ENSP00000262844 | ENSP00000487221 | AMMECR nuclear protein 1. | Protein FAM122B; Family with sequence similarity 122B; Belongs to the FAM122 family. | 0.453 |
C8orf58 | FAM122B | ENSP00000289989 | ENSP00000487221 | Uncharacterized protein C8orf58; Chromosome 8 open reading frame 58. | Protein FAM122B; Family with sequence similarity 122B; Belongs to the FAM122 family. | 0.475 |
FAM122A | FAM122B | ENSP00000377807 | ENSP00000487221 | Protein FAM122A; Acts as an inhibitor of serine/threonine-protein phosphatase 2A (PP2A) activity. Potentiates ubiquitin-mediated proteasomal degradation of serine/threonine-protein phosphatase 2A catalytic subunit alpha (PPP2CA). | Protein FAM122B; Family with sequence similarity 122B; Belongs to the FAM122 family. | 0.821 |
FAM122B | AMMECR1 | ENSP00000487221 | ENSP00000262844 | Protein FAM122B; Family with sequence similarity 122B; Belongs to the FAM122 family. | AMMECR nuclear protein 1. | 0.453 |
FAM122B | C8orf58 | ENSP00000487221 | ENSP00000289989 | Protein FAM122B; Family with sequence similarity 122B; Belongs to the FAM122 family. | Uncharacterized protein C8orf58; Chromosome 8 open reading frame 58. | 0.475 |
FAM122B | FAM122A | ENSP00000487221 | ENSP00000377807 | Protein FAM122B; Family with sequence similarity 122B; Belongs to the FAM122 family. | Protein FAM122A; Acts as an inhibitor of serine/threonine-protein phosphatase 2A (PP2A) activity. Potentiates ubiquitin-mediated proteasomal degradation of serine/threonine-protein phosphatase 2A catalytic subunit alpha (PPP2CA). | 0.821 |
FAM122B | FHL3 | ENSP00000487221 | ENSP00000362107 | Protein FAM122B; Family with sequence similarity 122B; Belongs to the FAM122 family. | Four and a half LIM domains protein 3; Recruited by SOX15 to FOXK1 promoters where it acts as a transcriptional coactivator of FOXK1. | 0.434 |
FAM122B | INTS6L | ENSP00000487221 | ENSP00000491427 | Protein FAM122B; Family with sequence similarity 122B; Belongs to the FAM122 family. | Integrator complex subunit 6 like. | 0.451 |
FAM122B | PAGE2B | ENSP00000487221 | ENSP00000364110 | Protein FAM122B; Family with sequence similarity 122B; Belongs to the FAM122 family. | PAGE family member 2B; Belongs to the GAGE family. | 0.434 |
FAM122B | PHF6 | ENSP00000487221 | ENSP00000329097 | Protein FAM122B; Family with sequence similarity 122B; Belongs to the FAM122 family. | PHD finger protein 6; Transcriptional regulator that associates with ribosomal RNA promoters and suppresses ribosomal RNA (rRNA) transcription. | 0.501 |
FAM122B | SFN | ENSP00000487221 | ENSP00000340989 | Protein FAM122B; Family with sequence similarity 122B; Belongs to the FAM122 family. | 14-3-3 protein sigma; Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway. May also regulate MDM2 autoubiquitination and degradation and thereby activate p53/TP53; Belongs to the 14-3-3 family. | 0.469 |
FAM122B | TTC13 | ENSP00000487221 | ENSP00000355621 | Protein FAM122B; Family with sequence similarity 122B; Belongs to the FAM122 family. | Tetratricopeptide repeat domain 13. | 0.496 |
FAM122B | VBP1 | ENSP00000487221 | ENSP00000286428 | Protein FAM122B; Family with sequence similarity 122B; Belongs to the FAM122 family. | Prefoldin subunit 3; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit alpha family. | 0.547 |
FHL3 | FAM122B | ENSP00000362107 | ENSP00000487221 | Four and a half LIM domains protein 3; Recruited by SOX15 to FOXK1 promoters where it acts as a transcriptional coactivator of FOXK1. | Protein FAM122B; Family with sequence similarity 122B; Belongs to the FAM122 family. | 0.434 |
INTS6L | FAM122B | ENSP00000491427 | ENSP00000487221 | Integrator complex subunit 6 like. | Protein FAM122B; Family with sequence similarity 122B; Belongs to the FAM122 family. | 0.451 |
PAGE2B | FAM122B | ENSP00000364110 | ENSP00000487221 | PAGE family member 2B; Belongs to the GAGE family. | Protein FAM122B; Family with sequence similarity 122B; Belongs to the FAM122 family. | 0.434 |
PHF6 | FAM122B | ENSP00000329097 | ENSP00000487221 | PHD finger protein 6; Transcriptional regulator that associates with ribosomal RNA promoters and suppresses ribosomal RNA (rRNA) transcription. | Protein FAM122B; Family with sequence similarity 122B; Belongs to the FAM122 family. | 0.501 |
SFN | FAM122B | ENSP00000340989 | ENSP00000487221 | 14-3-3 protein sigma; Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway. May also regulate MDM2 autoubiquitination and degradation and thereby activate p53/TP53; Belongs to the 14-3-3 family. | Protein FAM122B; Family with sequence similarity 122B; Belongs to the FAM122 family. | 0.469 |
TTC13 | FAM122B | ENSP00000355621 | ENSP00000487221 | Tetratricopeptide repeat domain 13. | Protein FAM122B; Family with sequence similarity 122B; Belongs to the FAM122 family. | 0.496 |
VBP1 | FAM122B | ENSP00000286428 | ENSP00000487221 | Prefoldin subunit 3; Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins; Belongs to the prefoldin subunit alpha family. | Protein FAM122B; Family with sequence similarity 122B; Belongs to the FAM122 family. | 0.547 |