STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RTL9Retrotransposon Gag like 9. (1388 aa)    
Predicted Functional Partners:
RTL6
Retrotransposon Gag like 6.
      
 0.810
RTL4
Retrotransposon Gag-like protein 4; Involved in cognitive function in the brain, possibly via the noradrenergic system.
      
 0.716
LDOC1
Protein LDOC1; May have an important role in the development and/or progression of some cancers; Belongs to the LDOC1 family.
  
  
 0.696
NUTM2G
NUT family member 2G.
    
 
 0.669
AMMECR1
AMMECR nuclear protein 1.
   
  
 0.664
TMEM164
Transmembrane protein 164; Belongs to the TMEM164 family.
   
  
 0.631
RTL8C
Retrotransposon Gag like 8C; Belongs to the FAM127 family.
   
  
 0.615
MAP7D2
MAP7 domain containing 2.
   
 
 0.556
NUGGC
Nuclear GTPase SLIP-GC; Nuclear GTPase found in germinal center B-cells, where it may inhibit function of the activation-induced cytidine deaminase AICDA. Reduces somatic hypermutation in B-cells which may enhance genome stability (By similarity).
      
 0.541
FANCM
Fanconi anemia group M protein; DNA-dependent ATPase component of the Fanconi anemia (FA) core complex. Required for the normal activation of the FA pathway, leading to monoubiquitination of the FANCI-FANCD2 complex in response to DNA damage, cellular resistance to DNA cross- linking drugs, and prevention of chromosomal breakage. In complex with CENPS and CENPX, binds double-stranded DNA (dsDNA), fork- structured DNA (fsDNA) and Holliday junction substrates. Its ATP-dependent DNA branch migration activity can process branched DNA structures such as a movable replication fork. This acti [...]
    
 
 0.532
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.