STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PXT1Peroxisomal testis enriched protein 1. (134 aa)    
Predicted Functional Partners:
PEX13
Peroxisomal membrane protein PEX13; Component of the peroxisomal translocation machinery with PEX14 and PEX17. Functions as a docking factor for the predominantly cytoplasmic PTS1 receptor (PAS10/PEX5). Involved in the import of PTS1 and PTS2 proteins.
      
 0.508
LMOD2
Leiomodin-2; Mediates nucleation of actin filaments and thereby promotes actin polymerization. Plays a role in the regulation of actin filament length (By similarity). Required for normal sarcomere organization in the heart, and for normal heart function.
      
 0.462
KCTD20
BTB/POZ domain-containing protein KCTD20; Promotes the phosphorylation of AKT family members.
      
 0.445
GNPAT
Glyceronephosphate O-acyltransferase.
      
 0.443
RTN1
Reticulon-1; May be involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells.
      
 0.439
APOL6
Apolipoprotein L6; May affect the movement of lipids in the cytoplasm or allow the binding of lipids to organelles.
      
 0.421
BNIP5
BCL2 interacting protein 5.
      
 0.418
NKX1-1
NK1 transcription factor-related protein 1; NK1 homeobox 1; Belongs to the NK-1 homeobox family.
      
 0.417
RFX8
DNA-binding protein RFX8; May be a transcription factor; Belongs to the RFX family.
      
 0.415
ETV7
Transcription factor ETV7; Transcriptional repressor; binds to the DNA sequence 5'- CCGGAAGT-3'. Isoform A does not seem to have a repressor activity. Isoform C does not seem to have a repressor activity; Belongs to the ETS family.
 
 
  
 0.414
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.