EFCAB12 protein (human) - STRING interaction network

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Score

EFCAB12

EF-hand calcium-binding domain-containing protein 12; EF-hand calcium binding domain 12. (572 aa)

Predicted Functional Partners:

CFAP44

0.611

CCDC151

0.602

CCDC89

0.600

MFSD13A

0.477

KIAA2012

0.472

KHDC4

0.461

MPV17L2

0.412

WDPCP

0.410

CIART

0.410

MRPS33

0.408

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCDC151	EFCAB12	ENSP00000348757	ENSP00000420854	Coiled-coil domain-containing protein 151; Ciliary protein involved in outer dynein arm assembly and required for motile cilia function.	EF-hand calcium-binding domain-containing protein 12; EF-hand calcium binding domain 12.	0.602
CCDC89	EFCAB12	ENSP00000320649	ENSP00000420854	Coiled-coil domain containing 89; Belongs to the CCDC89 family.	EF-hand calcium-binding domain-containing protein 12; EF-hand calcium binding domain 12.	0.600
CFAP44	EFCAB12	ENSP00000377428	ENSP00000420854	Cilia- and flagella-associated protein 44; Flagellar protein involved in sperm flagellum axoneme organization and function.	EF-hand calcium-binding domain-containing protein 12; EF-hand calcium binding domain 12.	0.611
CIART	EFCAB12	ENSP00000290363	ENSP00000420854	Circadian-associated transcriptional repressor; Transcriptional repressor which forms a negative regulatory component of the circadian clock and acts independently of the circadian transcriptional repressors: CRY1, CRY2 and BHLHE41. In a histone deacetylase-dependent manner represses the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer. Abrogates the interaction of ARNTL/BMAL1 with the transcriptional coactivator CREBBP and can repress the histone acetyl-transferase activity of the CLOCK- ARNTL/BMAL1 heterodimer, reducing histone acetylation of its target genes. [...]	EF-hand calcium-binding domain-containing protein 12; EF-hand calcium binding domain 12.	0.410
EFCAB12	CCDC151	ENSP00000420854	ENSP00000348757	EF-hand calcium-binding domain-containing protein 12; EF-hand calcium binding domain 12.	Coiled-coil domain-containing protein 151; Ciliary protein involved in outer dynein arm assembly and required for motile cilia function.	0.602
EFCAB12	CCDC89	ENSP00000420854	ENSP00000320649	EF-hand calcium-binding domain-containing protein 12; EF-hand calcium binding domain 12.	Coiled-coil domain containing 89; Belongs to the CCDC89 family.	0.600
EFCAB12	CFAP44	ENSP00000420854	ENSP00000377428	EF-hand calcium-binding domain-containing protein 12; EF-hand calcium binding domain 12.	Cilia- and flagella-associated protein 44; Flagellar protein involved in sperm flagellum axoneme organization and function.	0.611
EFCAB12	CIART	ENSP00000420854	ENSP00000290363	EF-hand calcium-binding domain-containing protein 12; EF-hand calcium binding domain 12.	Circadian-associated transcriptional repressor; Transcriptional repressor which forms a negative regulatory component of the circadian clock and acts independently of the circadian transcriptional repressors: CRY1, CRY2 and BHLHE41. In a histone deacetylase-dependent manner represses the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer. Abrogates the interaction of ARNTL/BMAL1 with the transcriptional coactivator CREBBP and can repress the histone acetyl-transferase activity of the CLOCK- ARNTL/BMAL1 heterodimer, reducing histone acetylation of its target genes. [...]	0.410
EFCAB12	KHDC4	ENSP00000420854	ENSP00000357304	EF-hand calcium-binding domain-containing protein 12; EF-hand calcium binding domain 12.	KH homology domain-containing protein 4; RNA-binding protein involved in pre-mRNA splicing. Interacts with the PRP19C/Prp19 complex/NTC/Nineteen complex which is part of the spliceosome. Involved in regulating splice site selection. Binds preferentially RNA with A/C rich sequences and poly-C stretches ; Belongs to the KHDC4 family.	0.461
EFCAB12	KIAA2012	ENSP00000420854	ENSP00000419834	EF-hand calcium-binding domain-containing protein 12; EF-hand calcium binding domain 12.	Uncharacterized protein KIAA2012; KIAA2012.	0.472
EFCAB12	MFSD13A	ENSP00000420854	ENSP00000238936	EF-hand calcium-binding domain-containing protein 12; EF-hand calcium binding domain 12.	Transmembrane protein 180; Major facilitator superfamily domain containing 13A.	0.477
EFCAB12	MPV17L2	ENSP00000420854	ENSP00000469836	EF-hand calcium-binding domain-containing protein 12; EF-hand calcium binding domain 12.	Mpv17-like protein 2; Required for the assembly and stability of the mitochondrial ribosome. Is a positive regulator of mitochondrial protein synthesis ; Belongs to the peroxisomal membrane protein PXMP2/4 family.	0.412
EFCAB12	MRPS33	ENSP00000420854	ENSP00000320567	EF-hand calcium-binding domain-containing protein 12; EF-hand calcium binding domain 12.	Mitochondrial ribosomal protein S33; Belongs to the mitochondrion-specific ribosomal protein mS33 family.	0.408
EFCAB12	WDPCP	ENSP00000420854	ENSP00000272321	EF-hand calcium-binding domain-containing protein 12; EF-hand calcium binding domain 12.	WD repeat-containing and planar cell polarity effector protein fritz homolog; Probable effector of the planar cell polarity signaling pathway which regulates the septin cytoskeleton in both ciliogenesis and collective cell movements. Together with FUZ and WDPCP proposed to function as core component of the CPLANE (ciliogenesis and planar polarity effectors) complex involved in the recruitment of peripheral IFT-A proteins to basal bodies (By similarity).	0.410
KHDC4	EFCAB12	ENSP00000357304	ENSP00000420854	KH homology domain-containing protein 4; RNA-binding protein involved in pre-mRNA splicing. Interacts with the PRP19C/Prp19 complex/NTC/Nineteen complex which is part of the spliceosome. Involved in regulating splice site selection. Binds preferentially RNA with A/C rich sequences and poly-C stretches ; Belongs to the KHDC4 family.	EF-hand calcium-binding domain-containing protein 12; EF-hand calcium binding domain 12.	0.461
KIAA2012	EFCAB12	ENSP00000419834	ENSP00000420854	Uncharacterized protein KIAA2012; KIAA2012.	EF-hand calcium-binding domain-containing protein 12; EF-hand calcium binding domain 12.	0.472
MFSD13A	EFCAB12	ENSP00000238936	ENSP00000420854	Transmembrane protein 180; Major facilitator superfamily domain containing 13A.	EF-hand calcium-binding domain-containing protein 12; EF-hand calcium binding domain 12.	0.477
MPV17L2	EFCAB12	ENSP00000469836	ENSP00000420854	Mpv17-like protein 2; Required for the assembly and stability of the mitochondrial ribosome. Is a positive regulator of mitochondrial protein synthesis ; Belongs to the peroxisomal membrane protein PXMP2/4 family.	EF-hand calcium-binding domain-containing protein 12; EF-hand calcium binding domain 12.	0.412
MRPS33	EFCAB12	ENSP00000320567	ENSP00000420854	Mitochondrial ribosomal protein S33; Belongs to the mitochondrion-specific ribosomal protein mS33 family.	EF-hand calcium-binding domain-containing protein 12; EF-hand calcium binding domain 12.	0.408
WDPCP	EFCAB12	ENSP00000272321	ENSP00000420854	WD repeat-containing and planar cell polarity effector protein fritz homolog; Probable effector of the planar cell polarity signaling pathway which regulates the septin cytoskeleton in both ciliogenesis and collective cell movements. Together with FUZ and WDPCP proposed to function as core component of the CPLANE (ciliogenesis and planar polarity effectors) complex involved in the recruitment of peripheral IFT-A proteins to basal bodies (By similarity).	EF-hand calcium-binding domain-containing protein 12; EF-hand calcium binding domain 12.	0.410