node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
OR1E1 | SPATA18 | ENSP00000313384 | ENSP00000295213 | Olfactory receptor 1E1; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | Mitochondria-eating protein; Key regulator of mitochondrial quality that mediates the repairing or degradation of unhealthy mitochondria in response to mitochondrial damage. Mediator of mitochondrial protein catabolic process (also named MALM) by mediating the degradation of damaged proteins inside mitochondria by promoting the accumulation in the mitochondrial matrix of hydrolases that are characteristic of the lysosomal lumen. Also involved in mitochondrion degradation of damaged mitochondria by promoting the formation of vacuole-like structures (named MIV), which engulf and degrade [...] | 0.600 |
OR1E1 | SPINK13 | ENSP00000313384 | ENSP00000421048 | Olfactory receptor 1E1; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | Serine protease inhibitor Kazal-type 13; May be a serine protease inhibitor (By similarity). Essential for sperm maturation and fertility. Inhibits sperm acrosome reaction, protecting sperm from premature reaction (By similarity). | 0.520 |
OR1E1 | SPINK14 | ENSP00000313384 | ENSP00000349459 | Olfactory receptor 1E1; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | Serine protease inhibitor Kazal-type 14; May be a serine protease inhibitor. | 0.648 |
OR1E1 | SPINK7 | ENSP00000313384 | ENSP00000274565 | Olfactory receptor 1E1; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | Serine protease inhibitor Kazal-type 7; Probable serine protease inhibitor. | 0.531 |
OR1E1 | SPINK9 | ENSP00000313384 | ENSP00000367139 | Olfactory receptor 1E1; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | Serine protease inhibitor Kazal-type 9; Serine protease inhibitor which specifically inhibits KLK5. May contribute to the regulation of the desquamation process in skin by inhibiting KLK5. | 0.589 |
SPATA18 | OR1E1 | ENSP00000295213 | ENSP00000313384 | Mitochondria-eating protein; Key regulator of mitochondrial quality that mediates the repairing or degradation of unhealthy mitochondria in response to mitochondrial damage. Mediator of mitochondrial protein catabolic process (also named MALM) by mediating the degradation of damaged proteins inside mitochondria by promoting the accumulation in the mitochondrial matrix of hydrolases that are characteristic of the lysosomal lumen. Also involved in mitochondrion degradation of damaged mitochondria by promoting the formation of vacuole-like structures (named MIV), which engulf and degrade [...] | Olfactory receptor 1E1; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | 0.600 |
SPATA18 | SPINK13 | ENSP00000295213 | ENSP00000421048 | Mitochondria-eating protein; Key regulator of mitochondrial quality that mediates the repairing or degradation of unhealthy mitochondria in response to mitochondrial damage. Mediator of mitochondrial protein catabolic process (also named MALM) by mediating the degradation of damaged proteins inside mitochondria by promoting the accumulation in the mitochondrial matrix of hydrolases that are characteristic of the lysosomal lumen. Also involved in mitochondrion degradation of damaged mitochondria by promoting the formation of vacuole-like structures (named MIV), which engulf and degrade [...] | Serine protease inhibitor Kazal-type 13; May be a serine protease inhibitor (By similarity). Essential for sperm maturation and fertility. Inhibits sperm acrosome reaction, protecting sperm from premature reaction (By similarity). | 0.484 |
SPATA18 | SPINK14 | ENSP00000295213 | ENSP00000349459 | Mitochondria-eating protein; Key regulator of mitochondrial quality that mediates the repairing or degradation of unhealthy mitochondria in response to mitochondrial damage. Mediator of mitochondrial protein catabolic process (also named MALM) by mediating the degradation of damaged proteins inside mitochondria by promoting the accumulation in the mitochondrial matrix of hydrolases that are characteristic of the lysosomal lumen. Also involved in mitochondrion degradation of damaged mitochondria by promoting the formation of vacuole-like structures (named MIV), which engulf and degrade [...] | Serine protease inhibitor Kazal-type 14; May be a serine protease inhibitor. | 0.538 |
SPATA18 | SPINK7 | ENSP00000295213 | ENSP00000274565 | Mitochondria-eating protein; Key regulator of mitochondrial quality that mediates the repairing or degradation of unhealthy mitochondria in response to mitochondrial damage. Mediator of mitochondrial protein catabolic process (also named MALM) by mediating the degradation of damaged proteins inside mitochondria by promoting the accumulation in the mitochondrial matrix of hydrolases that are characteristic of the lysosomal lumen. Also involved in mitochondrion degradation of damaged mitochondria by promoting the formation of vacuole-like structures (named MIV), which engulf and degrade [...] | Serine protease inhibitor Kazal-type 7; Probable serine protease inhibitor. | 0.460 |
SPATA18 | SPINK9 | ENSP00000295213 | ENSP00000367139 | Mitochondria-eating protein; Key regulator of mitochondrial quality that mediates the repairing or degradation of unhealthy mitochondria in response to mitochondrial damage. Mediator of mitochondrial protein catabolic process (also named MALM) by mediating the degradation of damaged proteins inside mitochondria by promoting the accumulation in the mitochondrial matrix of hydrolases that are characteristic of the lysosomal lumen. Also involved in mitochondrion degradation of damaged mitochondria by promoting the formation of vacuole-like structures (named MIV), which engulf and degrade [...] | Serine protease inhibitor Kazal-type 9; Serine protease inhibitor which specifically inhibits KLK5. May contribute to the regulation of the desquamation process in skin by inhibiting KLK5. | 0.486 |
SPINK1 | SPINK13 | ENSP00000296695 | ENSP00000421048 | Serine protease inhibitor Kazal-type 1; Serine protease inhibitor which exhibits anti-trypsin activity. In the pancreas, protects against trypsin- catalyzed premature activation of zymogens (By similarity). | Serine protease inhibitor Kazal-type 13; May be a serine protease inhibitor (By similarity). Essential for sperm maturation and fertility. Inhibits sperm acrosome reaction, protecting sperm from premature reaction (By similarity). | 0.506 |
SPINK1 | SPINK2 | ENSP00000296695 | ENSP00000425961 | Serine protease inhibitor Kazal-type 1; Serine protease inhibitor which exhibits anti-trypsin activity. In the pancreas, protects against trypsin- catalyzed premature activation of zymogens (By similarity). | Serine peptidase inhibitor Kazal type 2. | 0.899 |
SPINK1 | SPINK4 | ENSP00000296695 | ENSP00000369045 | Serine protease inhibitor Kazal-type 1; Serine protease inhibitor which exhibits anti-trypsin activity. In the pancreas, protects against trypsin- catalyzed premature activation of zymogens (By similarity). | Serine peptidase inhibitor Kazal type 4. | 0.445 |
SPINK1 | SPINK6 | ENSP00000296695 | ENSP00000481309 | Serine protease inhibitor Kazal-type 1; Serine protease inhibitor which exhibits anti-trypsin activity. In the pancreas, protects against trypsin- catalyzed premature activation of zymogens (By similarity). | Serine protease inhibitor Kazal-type 6; Serine protease inhibitor selective for kallikreins. Efficiently inhibits KLK4, KLK5, KLK6, KLK7, KLK12, KLK13 and KLK14. Doesn't inhibit KLK8. | 0.440 |
SPINK1 | SPINK7 | ENSP00000296695 | ENSP00000274565 | Serine protease inhibitor Kazal-type 1; Serine protease inhibitor which exhibits anti-trypsin activity. In the pancreas, protects against trypsin- catalyzed premature activation of zymogens (By similarity). | Serine protease inhibitor Kazal-type 7; Probable serine protease inhibitor. | 0.406 |
SPINK13 | OR1E1 | ENSP00000421048 | ENSP00000313384 | Serine protease inhibitor Kazal-type 13; May be a serine protease inhibitor (By similarity). Essential for sperm maturation and fertility. Inhibits sperm acrosome reaction, protecting sperm from premature reaction (By similarity). | Olfactory receptor 1E1; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | 0.520 |
SPINK13 | SPATA18 | ENSP00000421048 | ENSP00000295213 | Serine protease inhibitor Kazal-type 13; May be a serine protease inhibitor (By similarity). Essential for sperm maturation and fertility. Inhibits sperm acrosome reaction, protecting sperm from premature reaction (By similarity). | Mitochondria-eating protein; Key regulator of mitochondrial quality that mediates the repairing or degradation of unhealthy mitochondria in response to mitochondrial damage. Mediator of mitochondrial protein catabolic process (also named MALM) by mediating the degradation of damaged proteins inside mitochondria by promoting the accumulation in the mitochondrial matrix of hydrolases that are characteristic of the lysosomal lumen. Also involved in mitochondrion degradation of damaged mitochondria by promoting the formation of vacuole-like structures (named MIV), which engulf and degrade [...] | 0.484 |
SPINK13 | SPINK1 | ENSP00000421048 | ENSP00000296695 | Serine protease inhibitor Kazal-type 13; May be a serine protease inhibitor (By similarity). Essential for sperm maturation and fertility. Inhibits sperm acrosome reaction, protecting sperm from premature reaction (By similarity). | Serine protease inhibitor Kazal-type 1; Serine protease inhibitor which exhibits anti-trypsin activity. In the pancreas, protects against trypsin- catalyzed premature activation of zymogens (By similarity). | 0.506 |
SPINK13 | SPINK14 | ENSP00000421048 | ENSP00000349459 | Serine protease inhibitor Kazal-type 13; May be a serine protease inhibitor (By similarity). Essential for sperm maturation and fertility. Inhibits sperm acrosome reaction, protecting sperm from premature reaction (By similarity). | Serine protease inhibitor Kazal-type 14; May be a serine protease inhibitor. | 0.607 |
SPINK13 | SPINK2 | ENSP00000421048 | ENSP00000425961 | Serine protease inhibitor Kazal-type 13; May be a serine protease inhibitor (By similarity). Essential for sperm maturation and fertility. Inhibits sperm acrosome reaction, protecting sperm from premature reaction (By similarity). | Serine peptidase inhibitor Kazal type 2. | 0.629 |