| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DTNA | EFCAB11 | ENSP00000470152 | ENSP00000326267 | Dystrobrevin alpha; May be involved in the formation and stability of synapses as well as being involved in the clustering of nicotinic acetylcholine receptors. | EF-hand calcium-binding domain-containing protein 11; EF-hand calcium binding domain 11. | 0.547 |
| DTNA | IQCK | ENSP00000470152 | ENSP00000324901 | Dystrobrevin alpha; May be involved in the formation and stability of synapses as well as being involved in the clustering of nicotinic acetylcholine receptors. | IQ motif containing K. | 0.503 |
| DTNA | MCTP1 | ENSP00000470152 | ENSP00000424126 | Dystrobrevin alpha; May be involved in the formation and stability of synapses as well as being involved in the clustering of nicotinic acetylcholine receptors. | Multiple C2 and transmembrane domain-containing protein 1; Calcium sensor which is essential for the stabilization of normal baseline neurotransmitter release and for the induction and long-term maintenance of presynaptic homeostatic plasticity. Belongs to the MCTP family. | 0.496 |
| EFCAB11 | DTNA | ENSP00000326267 | ENSP00000470152 | EF-hand calcium-binding domain-containing protein 11; EF-hand calcium binding domain 11. | Dystrobrevin alpha; May be involved in the formation and stability of synapses as well as being involved in the clustering of nicotinic acetylcholine receptors. | 0.547 |
| EFCAB11 | IQCK | ENSP00000326267 | ENSP00000324901 | EF-hand calcium-binding domain-containing protein 11; EF-hand calcium binding domain 11. | IQ motif containing K. | 0.681 |
| EFCAB11 | MAP4K3 | ENSP00000326267 | ENSP00000263881 | EF-hand calcium-binding domain-containing protein 11; EF-hand calcium binding domain 11. | Mitogen-activated protein kinase kinase kinase kinase 3; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. | 0.545 |
| EFCAB11 | MCTP1 | ENSP00000326267 | ENSP00000424126 | EF-hand calcium-binding domain-containing protein 11; EF-hand calcium binding domain 11. | Multiple C2 and transmembrane domain-containing protein 1; Calcium sensor which is essential for the stabilization of normal baseline neurotransmitter release and for the induction and long-term maintenance of presynaptic homeostatic plasticity. Belongs to the MCTP family. | 0.646 |
| FAM172A | MCTP1 | ENSP00000379294 | ENSP00000424126 | Cotranscriptional regulator FAM172A; Plays a role in the regulation of alternative splicing, by interacting with AGO2 and CHD7. Seems to be required for stabilizing protein-protein interactions at the chromatin-spliceosome interface. May have hydrolase activity; Belongs to the FAM172 family. | Multiple C2 and transmembrane domain-containing protein 1; Calcium sensor which is essential for the stabilization of normal baseline neurotransmitter release and for the induction and long-term maintenance of presynaptic homeostatic plasticity. Belongs to the MCTP family. | 0.519 |
| FAM172A | SLF1 | ENSP00000379294 | ENSP00000265140 | Cotranscriptional regulator FAM172A; Plays a role in the regulation of alternative splicing, by interacting with AGO2 and CHD7. Seems to be required for stabilizing protein-protein interactions at the chromatin-spliceosome interface. May have hydrolase activity; Belongs to the FAM172 family. | SMC5-SMC6 complex localization factor protein 1; Plays a role in the DNA damage response (DDR) pathway by regulating postreplication repair of UV-damaged DNA and genomic stability maintenance. The SLF1-SLF2 complex acts to link RAD18 with the SMC5-SMC6 complex at replication-coupled interstrand cross-links (ICL) and DNA double-strand breaks (DSBs) sites on chromatin during DNA repair in response to stalled replication forks. Promotes the recruitment of SLF2 and the SMC5-SMC6 complex to DNA lesions. | 0.546 |
| IQCK | DTNA | ENSP00000324901 | ENSP00000470152 | IQ motif containing K. | Dystrobrevin alpha; May be involved in the formation and stability of synapses as well as being involved in the clustering of nicotinic acetylcholine receptors. | 0.503 |
| IQCK | EFCAB11 | ENSP00000324901 | ENSP00000326267 | IQ motif containing K. | EF-hand calcium-binding domain-containing protein 11; EF-hand calcium binding domain 11. | 0.681 |
| IQCK | MAP4K3 | ENSP00000324901 | ENSP00000263881 | IQ motif containing K. | Mitogen-activated protein kinase kinase kinase kinase 3; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. | 0.492 |
| IQCK | MCTP1 | ENSP00000324901 | ENSP00000424126 | IQ motif containing K. | Multiple C2 and transmembrane domain-containing protein 1; Calcium sensor which is essential for the stabilization of normal baseline neurotransmitter release and for the induction and long-term maintenance of presynaptic homeostatic plasticity. Belongs to the MCTP family. | 0.601 |
| MAP4K3 | EFCAB11 | ENSP00000263881 | ENSP00000326267 | Mitogen-activated protein kinase kinase kinase kinase 3; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. | EF-hand calcium-binding domain-containing protein 11; EF-hand calcium binding domain 11. | 0.545 |
| MAP4K3 | IQCK | ENSP00000263881 | ENSP00000324901 | Mitogen-activated protein kinase kinase kinase kinase 3; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. | IQ motif containing K. | 0.492 |
| MAP4K3 | MCTP1 | ENSP00000263881 | ENSP00000424126 | Mitogen-activated protein kinase kinase kinase kinase 3; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. | Multiple C2 and transmembrane domain-containing protein 1; Calcium sensor which is essential for the stabilization of normal baseline neurotransmitter release and for the induction and long-term maintenance of presynaptic homeostatic plasticity. Belongs to the MCTP family. | 0.509 |
| MAPT | MCTP1 | ENSP00000340820 | ENSP00000424126 | Microtubule-associated protein tau; Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its st [...] | Multiple C2 and transmembrane domain-containing protein 1; Calcium sensor which is essential for the stabilization of normal baseline neurotransmitter release and for the induction and long-term maintenance of presynaptic homeostatic plasticity. Belongs to the MCTP family. | 0.470 |
| MAPT | SV2B | ENSP00000340820 | ENSP00000377779 | Microtubule-associated protein tau; Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its st [...] | Synaptic vesicle glycoprotein 2B; Probably plays a role in the control of regulated secretion in neural and endocrine cells. | 0.552 |
| MCTP1 | DTNA | ENSP00000424126 | ENSP00000470152 | Multiple C2 and transmembrane domain-containing protein 1; Calcium sensor which is essential for the stabilization of normal baseline neurotransmitter release and for the induction and long-term maintenance of presynaptic homeostatic plasticity. Belongs to the MCTP family. | Dystrobrevin alpha; May be involved in the formation and stability of synapses as well as being involved in the clustering of nicotinic acetylcholine receptors. | 0.496 |
| MCTP1 | EFCAB11 | ENSP00000424126 | ENSP00000326267 | Multiple C2 and transmembrane domain-containing protein 1; Calcium sensor which is essential for the stabilization of normal baseline neurotransmitter release and for the induction and long-term maintenance of presynaptic homeostatic plasticity. Belongs to the MCTP family. | EF-hand calcium-binding domain-containing protein 11; EF-hand calcium binding domain 11. | 0.646 |
