node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CFAP45 | MCTP1 | ENSP00000357079 | ENSP00000424126 | Cilia and flagella associated protein 45. | Multiple C2 and transmembrane domain-containing protein 1; Calcium sensor which is essential for the stabilization of normal baseline neurotransmitter release and for the induction and long-term maintenance of presynaptic homeostatic plasticity. Belongs to the MCTP family. | 0.499 |
DCAF12L2 | MCTP1 | ENSP00000353128 | ENSP00000424126 | DDB1- and CUL4-associated factor 12-like protein 2; DDB1 and CUL4 associated factor 12 like 2; Belongs to the WD repeat DCAF12 family. | Multiple C2 and transmembrane domain-containing protein 1; Calcium sensor which is essential for the stabilization of normal baseline neurotransmitter release and for the induction and long-term maintenance of presynaptic homeostatic plasticity. Belongs to the MCTP family. | 0.469 |
DCAF12L2 | PRSS45P | ENSP00000353128 | ENSP00000401932 | DDB1- and CUL4-associated factor 12-like protein 2; DDB1 and CUL4 associated factor 12 like 2; Belongs to the WD repeat DCAF12 family. | Serine protease 45, pseudogene. | 0.598 |
EFCAB11 | IQCK | ENSP00000326267 | ENSP00000324901 | EF-hand calcium-binding domain-containing protein 11; EF-hand calcium binding domain 11. | IQ motif containing K. | 0.663 |
EFCAB11 | MAP4K3 | ENSP00000326267 | ENSP00000263881 | EF-hand calcium-binding domain-containing protein 11; EF-hand calcium binding domain 11. | Mitogen-activated protein kinase kinase kinase kinase 3; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. | 0.511 |
EFCAB11 | MCTP1 | ENSP00000326267 | ENSP00000424126 | EF-hand calcium-binding domain-containing protein 11; EF-hand calcium binding domain 11. | Multiple C2 and transmembrane domain-containing protein 1; Calcium sensor which is essential for the stabilization of normal baseline neurotransmitter release and for the induction and long-term maintenance of presynaptic homeostatic plasticity. Belongs to the MCTP family. | 0.618 |
FAM172A | MCTP1 | ENSP00000379294 | ENSP00000424126 | Cotranscriptional regulator FAM172A; Plays a role in the regulation of alternative splicing, by interacting with AGO2 and CHD7. Seems to be required for stabilizing protein-protein interactions at the chromatin-spliceosome interface. May have hydrolase activity; Belongs to the FAM172 family. | Multiple C2 and transmembrane domain-containing protein 1; Calcium sensor which is essential for the stabilization of normal baseline neurotransmitter release and for the induction and long-term maintenance of presynaptic homeostatic plasticity. Belongs to the MCTP family. | 0.557 |
FAM172A | SLF1 | ENSP00000379294 | ENSP00000265140 | Cotranscriptional regulator FAM172A; Plays a role in the regulation of alternative splicing, by interacting with AGO2 and CHD7. Seems to be required for stabilizing protein-protein interactions at the chromatin-spliceosome interface. May have hydrolase activity; Belongs to the FAM172 family. | SMC5-SMC6 complex localization factor protein 1; Plays a role in the DNA damage response (DDR) pathway by regulating postreplication repair of UV-damaged DNA and genomic stability maintenance. The SLF1-SLF2 complex acts to link RAD18 with the SMC5-SMC6 complex at replication-coupled interstrand cross-links (ICL) and DNA double-strand breaks (DSBs) sites on chromatin during DNA repair in response to stalled replication forks. Promotes the recruitment of SLF2 and the SMC5-SMC6 complex to DNA lesions. | 0.589 |
IQCK | EFCAB11 | ENSP00000324901 | ENSP00000326267 | IQ motif containing K. | EF-hand calcium-binding domain-containing protein 11; EF-hand calcium binding domain 11. | 0.663 |
IQCK | MAP4K3 | ENSP00000324901 | ENSP00000263881 | IQ motif containing K. | Mitogen-activated protein kinase kinase kinase kinase 3; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. | 0.456 |
IQCK | MCTP1 | ENSP00000324901 | ENSP00000424126 | IQ motif containing K. | Multiple C2 and transmembrane domain-containing protein 1; Calcium sensor which is essential for the stabilization of normal baseline neurotransmitter release and for the induction and long-term maintenance of presynaptic homeostatic plasticity. Belongs to the MCTP family. | 0.562 |
MAP4K3 | EFCAB11 | ENSP00000263881 | ENSP00000326267 | Mitogen-activated protein kinase kinase kinase kinase 3; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. | EF-hand calcium-binding domain-containing protein 11; EF-hand calcium binding domain 11. | 0.511 |
MAP4K3 | IQCK | ENSP00000263881 | ENSP00000324901 | Mitogen-activated protein kinase kinase kinase kinase 3; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. | IQ motif containing K. | 0.456 |
MAP4K3 | MCTP1 | ENSP00000263881 | ENSP00000424126 | Mitogen-activated protein kinase kinase kinase kinase 3; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. | Multiple C2 and transmembrane domain-containing protein 1; Calcium sensor which is essential for the stabilization of normal baseline neurotransmitter release and for the induction and long-term maintenance of presynaptic homeostatic plasticity. Belongs to the MCTP family. | 0.464 |
MCTP1 | CFAP45 | ENSP00000424126 | ENSP00000357079 | Multiple C2 and transmembrane domain-containing protein 1; Calcium sensor which is essential for the stabilization of normal baseline neurotransmitter release and for the induction and long-term maintenance of presynaptic homeostatic plasticity. Belongs to the MCTP family. | Cilia and flagella associated protein 45. | 0.499 |
MCTP1 | DCAF12L2 | ENSP00000424126 | ENSP00000353128 | Multiple C2 and transmembrane domain-containing protein 1; Calcium sensor which is essential for the stabilization of normal baseline neurotransmitter release and for the induction and long-term maintenance of presynaptic homeostatic plasticity. Belongs to the MCTP family. | DDB1- and CUL4-associated factor 12-like protein 2; DDB1 and CUL4 associated factor 12 like 2; Belongs to the WD repeat DCAF12 family. | 0.469 |
MCTP1 | EFCAB11 | ENSP00000424126 | ENSP00000326267 | Multiple C2 and transmembrane domain-containing protein 1; Calcium sensor which is essential for the stabilization of normal baseline neurotransmitter release and for the induction and long-term maintenance of presynaptic homeostatic plasticity. Belongs to the MCTP family. | EF-hand calcium-binding domain-containing protein 11; EF-hand calcium binding domain 11. | 0.618 |
MCTP1 | FAM172A | ENSP00000424126 | ENSP00000379294 | Multiple C2 and transmembrane domain-containing protein 1; Calcium sensor which is essential for the stabilization of normal baseline neurotransmitter release and for the induction and long-term maintenance of presynaptic homeostatic plasticity. Belongs to the MCTP family. | Cotranscriptional regulator FAM172A; Plays a role in the regulation of alternative splicing, by interacting with AGO2 and CHD7. Seems to be required for stabilizing protein-protein interactions at the chromatin-spliceosome interface. May have hydrolase activity; Belongs to the FAM172 family. | 0.557 |
MCTP1 | IQCK | ENSP00000424126 | ENSP00000324901 | Multiple C2 and transmembrane domain-containing protein 1; Calcium sensor which is essential for the stabilization of normal baseline neurotransmitter release and for the induction and long-term maintenance of presynaptic homeostatic plasticity. Belongs to the MCTP family. | IQ motif containing K. | 0.562 |
MCTP1 | MAP4K3 | ENSP00000424126 | ENSP00000263881 | Multiple C2 and transmembrane domain-containing protein 1; Calcium sensor which is essential for the stabilization of normal baseline neurotransmitter release and for the induction and long-term maintenance of presynaptic homeostatic plasticity. Belongs to the MCTP family. | Mitogen-activated protein kinase kinase kinase kinase 3; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. | 0.464 |