STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SATL1Spermidine/spermine N1-acetyl transferase like 1; GCN5 related N-acetyltransferases (632 aa)    
Predicted Functional Partners:
C1orf141
Uncharacterized protein C1orf141; Chromosome 1 open reading frame 141
      
 0.756
C8orf74
Uncharacterized protein C8orf74; Chromosome 8 open reading frame 74
      
 0.709
C3orf14
Uncharacterized protein C3orf14; Chromosome 3 open reading frame 14
      
 0.645
OR13A1
Olfactory receptor 13A1; Odorant receptor; Olfactory receptors, family 13
      
 0.630
ZNF652
Zinc finger protein 652; Functions as a transcriptional repressor; Zinc fingers C2H2-type
      
 0.570
APOOL
MICOS complex subunit MIC27; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Specifically binds to cardiolipin (in vitro) but not to the precursor lipid phosphatidylglycerol. Plays a crucial role in crista junction formation and mitochondrial function,
   
  
 0.566
ZNF711
Zinc finger protein 711; Transcription regulator required for brain development. Probably acts as a transcription factor that binds to the promoter of target genes and recruits PHF8 histone demethylase, leading to activate expression of genes involved in neuron development, such as KDM5C; Belongs to the krueppel C2H2-type zinc-finger protein family
      
 0.565
POF1B
Protein POF1B; Plays a key role in the organization of epithelial monolayers by regulating the actin cytoskeleton. May be involved in ovary development
      
 0.557
SHCBP1L
Testicular spindle-associated protein SHCBP1L; Testis-specific spindle-associated factor that plays a role in spermatogenesis. In association with HSPA2, participates in the maintenance of spindle integrity during meiosis in male germ cells
      
 0.557
FAM47B
Protein FAM47B; Family with sequence similarity 47 member B; Belongs to the FAM47 family
      
 0.555
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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