| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ARFIP1 | COMMD8 | ENSP00000395083 | ENSP00000370984 | Arfaptin-1; Putative target protein of ADP-ribosylation factor; Classical BAR domain containing | COMM domain-containing protein 8; May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. May down-regulate activation of NF-kappa-B | 0.680 |
| ARFIP1 | DDIT4L | ENSP00000395083 | ENSP00000354830 | Arfaptin-1; Putative target protein of ADP-ribosylation factor; Classical BAR domain containing | DNA damage-inducible transcript 4-like protein; Inhibits cell growth by regulating the TOR signaling pathway upstream of the TSC1-TSC2 complex and downstream of AKT1 | 0.688 |
| ARFIP1 | GABRB1 | ENSP00000395083 | ENSP00000295454 | Arfaptin-1; Putative target protein of ADP-ribosylation factor; Classical BAR domain containing | Gamma-aminobutyric acid receptor subunit beta-1; Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand- gated chloride channel; Gamma-aminobutyric acid type A receptor subunits | 0.680 |
| ARFIP1 | KIAA0922 | ENSP00000395083 | ENSP00000386787 | Arfaptin-1; Putative target protein of ADP-ribosylation factor; Classical BAR domain containing | Transmembrane protein 131-like; Isoform 1: Membrane-associated form that antagonizes canonical Wnt signaling by triggering lysosome-dependent degradation of Wnt-activated LRP6. Regulates thymocyte proliferation | 0.751 |
| ARFIP1 | LIAS | ENSP00000395083 | ENSP00000261434 | Arfaptin-1; Putative target protein of ADP-ribosylation factor; Classical BAR domain containing | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives | 0.695 |
| ARFIP1 | NDUFC1 | ENSP00000395083 | ENSP00000441126 | Arfaptin-1; Putative target protein of ADP-ribosylation factor; Classical BAR domain containing | NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone; NADH:ubiquinone oxidoreductase supernumerary subunits | 0.705 |
| ARFIP1 | OCIAD2 | ENSP00000395083 | ENSP00000423014 | Arfaptin-1; Putative target protein of ADP-ribosylation factor; Classical BAR domain containing | Ocia domain-containing protein 2; OCIA domain containing 2 | 0.730 |
| ARFIP1 | RNF150 | ENSP00000395083 | ENSP00000425840 | Arfaptin-1; Putative target protein of ADP-ribosylation factor; Classical BAR domain containing | Ring finger protein 150 | 0.721 |
| ARFIP1 | SYNPO2 | ENSP00000395083 | ENSP00000306015 | Arfaptin-1; Putative target protein of ADP-ribosylation factor; Classical BAR domain containing | Synaptopodin-2; Isoform 4: Can induce long, well-organized actin bundles frequently orientated in parallel along the long axis of the cell showing characteristics of contractile ventral stress fibers; Belongs to the synaptopodin family | 0.688 |
| ARFIP1 | TIGD4 | ENSP00000395083 | ENSP00000355162 | Arfaptin-1; Putative target protein of ADP-ribosylation factor; Classical BAR domain containing | Tigger transposable element-derived protein 4; Helix-turn-helix CENPB type domain containing; DNA transposon derived genes | 0.775 |
| COMMD8 | ARFIP1 | ENSP00000370984 | ENSP00000395083 | COMM domain-containing protein 8; May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. May down-regulate activation of NF-kappa-B | Arfaptin-1; Putative target protein of ADP-ribosylation factor; Classical BAR domain containing | 0.680 |
| COMMD8 | DDIT4L | ENSP00000370984 | ENSP00000354830 | COMM domain-containing protein 8; May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. May down-regulate activation of NF-kappa-B | DNA damage-inducible transcript 4-like protein; Inhibits cell growth by regulating the TOR signaling pathway upstream of the TSC1-TSC2 complex and downstream of AKT1 | 0.645 |
| COMMD8 | GABRB1 | ENSP00000370984 | ENSP00000295454 | COMM domain-containing protein 8; May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. May down-regulate activation of NF-kappa-B | Gamma-aminobutyric acid receptor subunit beta-1; Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand- gated chloride channel; Gamma-aminobutyric acid type A receptor subunits | 0.801 |
| COMMD8 | KIAA0922 | ENSP00000370984 | ENSP00000386787 | COMM domain-containing protein 8; May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. May down-regulate activation of NF-kappa-B | Transmembrane protein 131-like; Isoform 1: Membrane-associated form that antagonizes canonical Wnt signaling by triggering lysosome-dependent degradation of Wnt-activated LRP6. Regulates thymocyte proliferation | 0.719 |
| COMMD8 | LIAS | ENSP00000370984 | ENSP00000261434 | COMM domain-containing protein 8; May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. May down-regulate activation of NF-kappa-B | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives | 0.706 |
| COMMD8 | NDUFC1 | ENSP00000370984 | ENSP00000441126 | COMM domain-containing protein 8; May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. May down-regulate activation of NF-kappa-B | NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone; NADH:ubiquinone oxidoreductase supernumerary subunits | 0.631 |
| COMMD8 | OCIAD2 | ENSP00000370984 | ENSP00000423014 | COMM domain-containing protein 8; May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. May down-regulate activation of NF-kappa-B | Ocia domain-containing protein 2; OCIA domain containing 2 | 0.722 |
| COMMD8 | RNF150 | ENSP00000370984 | ENSP00000425840 | COMM domain-containing protein 8; May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. May down-regulate activation of NF-kappa-B | Ring finger protein 150 | 0.726 |
| COMMD8 | SYNPO2 | ENSP00000370984 | ENSP00000306015 | COMM domain-containing protein 8; May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. May down-regulate activation of NF-kappa-B | Synaptopodin-2; Isoform 4: Can induce long, well-organized actin bundles frequently orientated in parallel along the long axis of the cell showing characteristics of contractile ventral stress fibers; Belongs to the synaptopodin family | 0.644 |
| COMMD8 | TIGD4 | ENSP00000370984 | ENSP00000355162 | COMM domain-containing protein 8; May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes. May down-regulate activation of NF-kappa-B | Tigger transposable element-derived protein 4; Helix-turn-helix CENPB type domain containing; DNA transposon derived genes | 0.679 |
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