STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCDC169Coiled-coil domain containing 169. (241 aa)    
Predicted Functional Partners:
SOHLH2
Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 2; Transcription regulator of both male and female germline differentiation. Suppresses genes involved in spermatogonial stem cells maintenance, and induces genes important for spermatogonial differentiation. Coordinates oocyte differentiation without affecting meiosis I (By similarity).
 
 
  
 0.522
TMEM161B
Transmembrane protein 161B; Belongs to the TMEM161 family.
      
 0.509
CCDC190
Coiled-coil domain containing 190.
      
 0.478
CCDC74B
Coiled-coil domain containing 74B.
      
 0.476
PROSER1
Proline and serine rich 1.
      
 0.475
MAB21L1
Putative nucleotidyltransferase MAB21L1; Putative nucleotidyltransferase required for several aspects of embryonic development including normal development of the eye. It is unclear whether it displays nucleotidyltransferase activity in vivo. Binds single-stranded RNA (ssRNA). Belongs to the mab-21 family.
      
 0.471
CCDC125
Coiled-coil domain-containing protein 125; May be involved in the regulation of cell migration.
   
  
 0.453
STPG2
Sperm-tail PG-rich repeat-containing protein 2; Sperm tail PG-rich repeat containing 2.
   
  
 0.448
ZNF287
Zinc finger protein 287; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
      
 0.430
ZNF641
Zinc finger protein 641; Transcriptional activator. Activates transcriptional activities of SRE and AP-1; Belongs to the krueppel C2H2-type zinc-finger protein family.
      
 0.428
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.