C8orf34 protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASB7	C8orf34	ENSP00000328327	ENSP00000427820	Ankyrin repeat and SOCS box protein 7; Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; Belongs to the ankyrin SOCS box (ASB) family.	Uncharacterized protein C8orf34; Chromosome 8 open reading frame 34.	0.772
C8orf34	ASB7	ENSP00000427820	ENSP00000328327	Uncharacterized protein C8orf34; Chromosome 8 open reading frame 34.	Ankyrin repeat and SOCS box protein 7; Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; Belongs to the ankyrin SOCS box (ASB) family.	0.772
C8orf34	CALN1	ENSP00000427820	ENSP00000378690	Uncharacterized protein C8orf34; Chromosome 8 open reading frame 34.	Calcium-binding protein 8; Negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity (By similarity). May play a role in the physiology of neurons and is potentially important in memory and learning.	0.415
C8orf34	CPVL	ENSP00000427820	ENSP00000387164	Uncharacterized protein C8orf34; Chromosome 8 open reading frame 34.	Probable serine carboxypeptidase CPVL; May be involved in the digestion of phagocytosed particles in the lysosome, participation in an inflammatory protease cascade, and trimming of peptides for antigen presentation; Belongs to the peptidase S10 family.	0.457
C8orf34	TEX55	ENSP00000427820	ENSP00000295622	Uncharacterized protein C8orf34; Chromosome 8 open reading frame 34.	Testis expressed 55.	0.419
CALN1	C8orf34	ENSP00000378690	ENSP00000427820	Calcium-binding protein 8; Negatively regulates Golgi-to-plasma membrane trafficking by interacting with PI4KB and inhibiting its activity (By similarity). May play a role in the physiology of neurons and is potentially important in memory and learning.	Uncharacterized protein C8orf34; Chromosome 8 open reading frame 34.	0.415
CPVL	C8orf34	ENSP00000387164	ENSP00000427820	Probable serine carboxypeptidase CPVL; May be involved in the digestion of phagocytosed particles in the lysosome, participation in an inflammatory protease cascade, and trimming of peptides for antigen presentation; Belongs to the peptidase S10 family.	Uncharacterized protein C8orf34; Chromosome 8 open reading frame 34.	0.457
TEX55	C8orf34	ENSP00000295622	ENSP00000427820	Testis expressed 55.	Uncharacterized protein C8orf34; Chromosome 8 open reading frame 34.	0.419