node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HHLA3 | SLC10A5 | ENSP00000359978 | ENSP00000428612 | HERV-H LTR-associating 3. | Sodium/bile acid cotransporter 5; Solute carrier family 10 member 5. | 0.430 |
SLC10A4 | SLC10A5 | ENSP00000273861 | ENSP00000428612 | Sodium/bile acid cotransporter 4; Transporter for bile acids; Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family. | Sodium/bile acid cotransporter 5; Solute carrier family 10 member 5. | 0.421 |
SLC10A4 | SLC10A7 | ENSP00000273861 | ENSP00000421275 | Sodium/bile acid cotransporter 4; Transporter for bile acids; Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family. | Sodium/bile acid cotransporter 7; Involved in teeth and skeletal development. Has an essential role in the biosynthesis and trafficking of glycosaminoglycans and glycoproteins, to produce a proper functioning extracellular matrix. Required for extracellular matrix mineralization. Also involved in the regulation of cellular calcium homeostasis. Does not show transport activity towards bile acids or steroid sulfates (including taurocholate, cholate, chenodeoxycholate, estrone-3-sulfate, dehydroepiandrosterone sulfate (DHEAS) and pregnenolone sulfate). Belongs to the bile acid:sodium symp [...] | 0.690 |
SLC10A5 | HHLA3 | ENSP00000428612 | ENSP00000359978 | Sodium/bile acid cotransporter 5; Solute carrier family 10 member 5. | HERV-H LTR-associating 3. | 0.430 |
SLC10A5 | SLC10A4 | ENSP00000428612 | ENSP00000273861 | Sodium/bile acid cotransporter 5; Solute carrier family 10 member 5. | Sodium/bile acid cotransporter 4; Transporter for bile acids; Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family. | 0.421 |
SLC10A5 | SLC10A7 | ENSP00000428612 | ENSP00000421275 | Sodium/bile acid cotransporter 5; Solute carrier family 10 member 5. | Sodium/bile acid cotransporter 7; Involved in teeth and skeletal development. Has an essential role in the biosynthesis and trafficking of glycosaminoglycans and glycoproteins, to produce a proper functioning extracellular matrix. Required for extracellular matrix mineralization. Also involved in the regulation of cellular calcium homeostasis. Does not show transport activity towards bile acids or steroid sulfates (including taurocholate, cholate, chenodeoxycholate, estrone-3-sulfate, dehydroepiandrosterone sulfate (DHEAS) and pregnenolone sulfate). Belongs to the bile acid:sodium symp [...] | 0.793 |
SLC10A5 | SLC35E4 | ENSP00000428612 | ENSP00000339626 | Sodium/bile acid cotransporter 5; Solute carrier family 10 member 5. | Solute carrier family 35 member E4; Putative transporter. | 0.421 |
SLC10A5 | SLC51B | ENSP00000428612 | ENSP00000335292 | Sodium/bile acid cotransporter 5; Solute carrier family 10 member 5. | Organic solute transporter subunit beta; Essential component of the Ost-alpha/Ost-beta complex, a heterodimer that acts as the intestinal basolateral transporter responsible for bile acid export from enterocytes into portal blood. Efficiently transports the major species of bile acids. Modulates SLC51A glycosylation, membrane trafficking and stability activities. | 0.405 |
SLC10A5 | TMEM253 | ENSP00000428612 | ENSP00000453962 | Sodium/bile acid cotransporter 5; Solute carrier family 10 member 5. | Transmembrane protein 253. | 0.475 |
SLC10A5 | TMEM50A | ENSP00000428612 | ENSP00000363478 | Sodium/bile acid cotransporter 5; Solute carrier family 10 member 5. | Transmembrane protein 50A; Belongs to the UPF0220 family. | 0.403 |
SLC10A5 | ZFAND1 | ENSP00000428612 | ENSP00000220669 | Sodium/bile acid cotransporter 5; Solute carrier family 10 member 5. | AN1-type zinc finger protein 1; Plays a role in the regulation of cytoplasmic stress granules (SGs) turnover. SGs are dynamic and transient cytoplasmic ribonucleoprotein assemblies important for cellular protein homeostasis when protein production is suspended after acute exogenous stress. Associates with SGs and is involved in the efficient and specific arsenite-induced clearance process of SGs through the recruitment of the ubiquitin-selective ATPase VCP and the 26S proteasome. This process requires both complexes for efficient degradation of damaged ubiquitinated SG proteins during [...] | 0.486 |
SLC10A7 | SLC10A4 | ENSP00000421275 | ENSP00000273861 | Sodium/bile acid cotransporter 7; Involved in teeth and skeletal development. Has an essential role in the biosynthesis and trafficking of glycosaminoglycans and glycoproteins, to produce a proper functioning extracellular matrix. Required for extracellular matrix mineralization. Also involved in the regulation of cellular calcium homeostasis. Does not show transport activity towards bile acids or steroid sulfates (including taurocholate, cholate, chenodeoxycholate, estrone-3-sulfate, dehydroepiandrosterone sulfate (DHEAS) and pregnenolone sulfate). Belongs to the bile acid:sodium symp [...] | Sodium/bile acid cotransporter 4; Transporter for bile acids; Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family. | 0.690 |
SLC10A7 | SLC10A5 | ENSP00000421275 | ENSP00000428612 | Sodium/bile acid cotransporter 7; Involved in teeth and skeletal development. Has an essential role in the biosynthesis and trafficking of glycosaminoglycans and glycoproteins, to produce a proper functioning extracellular matrix. Required for extracellular matrix mineralization. Also involved in the regulation of cellular calcium homeostasis. Does not show transport activity towards bile acids or steroid sulfates (including taurocholate, cholate, chenodeoxycholate, estrone-3-sulfate, dehydroepiandrosterone sulfate (DHEAS) and pregnenolone sulfate). Belongs to the bile acid:sodium symp [...] | Sodium/bile acid cotransporter 5; Solute carrier family 10 member 5. | 0.793 |
SLC35E4 | SLC10A5 | ENSP00000339626 | ENSP00000428612 | Solute carrier family 35 member E4; Putative transporter. | Sodium/bile acid cotransporter 5; Solute carrier family 10 member 5. | 0.421 |
SLC51B | SLC10A5 | ENSP00000335292 | ENSP00000428612 | Organic solute transporter subunit beta; Essential component of the Ost-alpha/Ost-beta complex, a heterodimer that acts as the intestinal basolateral transporter responsible for bile acid export from enterocytes into portal blood. Efficiently transports the major species of bile acids. Modulates SLC51A glycosylation, membrane trafficking and stability activities. | Sodium/bile acid cotransporter 5; Solute carrier family 10 member 5. | 0.405 |
TMEM253 | SLC10A5 | ENSP00000453962 | ENSP00000428612 | Transmembrane protein 253. | Sodium/bile acid cotransporter 5; Solute carrier family 10 member 5. | 0.475 |
TMEM253 | TMEM50A | ENSP00000453962 | ENSP00000363478 | Transmembrane protein 253. | Transmembrane protein 50A; Belongs to the UPF0220 family. | 0.545 |
TMEM50A | SLC10A5 | ENSP00000363478 | ENSP00000428612 | Transmembrane protein 50A; Belongs to the UPF0220 family. | Sodium/bile acid cotransporter 5; Solute carrier family 10 member 5. | 0.403 |
TMEM50A | TMEM253 | ENSP00000363478 | ENSP00000453962 | Transmembrane protein 50A; Belongs to the UPF0220 family. | Transmembrane protein 253. | 0.545 |
ZFAND1 | SLC10A5 | ENSP00000220669 | ENSP00000428612 | AN1-type zinc finger protein 1; Plays a role in the regulation of cytoplasmic stress granules (SGs) turnover. SGs are dynamic and transient cytoplasmic ribonucleoprotein assemblies important for cellular protein homeostasis when protein production is suspended after acute exogenous stress. Associates with SGs and is involved in the efficient and specific arsenite-induced clearance process of SGs through the recruitment of the ubiquitin-selective ATPase VCP and the 26S proteasome. This process requires both complexes for efficient degradation of damaged ubiquitinated SG proteins during [...] | Sodium/bile acid cotransporter 5; Solute carrier family 10 member 5. | 0.486 |