MS4A18 protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MS4A10	MS4A18	ENSP00000311862	ENSP00000431607	Membrane-spanning 4-domains subfamily A member 10; May be involved in signal transduction as a component of a multimeric receptor complex; Belongs to the MS4A family.	Membrane spanning 4-domains A18.	0.750
MS4A10	MS4A5	ENSP00000311862	ENSP00000300190	Membrane-spanning 4-domains subfamily A member 10; May be involved in signal transduction as a component of a multimeric receptor complex; Belongs to the MS4A family.	Membrane-spanning 4-domains subfamily A member 5; May be involved in signal transduction as a component of a multimeric receptor complex.	0.679
MS4A10	MS4A6A	ENSP00000311862	ENSP00000435844	Membrane-spanning 4-domains subfamily A member 10; May be involved in signal transduction as a component of a multimeric receptor complex; Belongs to the MS4A family.	Membrane-spanning 4-domains subfamily A member 6A; May be involved in signal transduction as a component of a multimeric receptor complex; Belongs to the MS4A family.	0.871
MS4A10	MS4A6E	ENSP00000311862	ENSP00000300182	Membrane-spanning 4-domains subfamily A member 10; May be involved in signal transduction as a component of a multimeric receptor complex; Belongs to the MS4A family.	Membrane-spanning 4-domains subfamily A member 6E; May be involved in signal transduction as a component of a multimeric receptor complex.	0.945
MS4A14	MS4A18	ENSP00000433761	ENSP00000431607	Membrane-spanning 4-domains subfamily A member 14; May be involved in signal transduction as a component of a multimeric receptor complex.	Membrane spanning 4-domains A18.	0.659
MS4A14	MS4A6E	ENSP00000433761	ENSP00000300182	Membrane-spanning 4-domains subfamily A member 14; May be involved in signal transduction as a component of a multimeric receptor complex.	Membrane-spanning 4-domains subfamily A member 6E; May be involved in signal transduction as a component of a multimeric receptor complex.	0.548
MS4A14	TMEM176A	ENSP00000433761	ENSP00000417626	Membrane-spanning 4-domains subfamily A member 14; May be involved in signal transduction as a component of a multimeric receptor complex.	Transmembrane protein 176A.	0.424
MS4A18	MS4A10	ENSP00000431607	ENSP00000311862	Membrane spanning 4-domains A18.	Membrane-spanning 4-domains subfamily A member 10; May be involved in signal transduction as a component of a multimeric receptor complex; Belongs to the MS4A family.	0.750
MS4A18	MS4A14	ENSP00000431607	ENSP00000433761	Membrane spanning 4-domains A18.	Membrane-spanning 4-domains subfamily A member 14; May be involved in signal transduction as a component of a multimeric receptor complex.	0.659
MS4A18	MS4A5	ENSP00000431607	ENSP00000300190	Membrane spanning 4-domains A18.	Membrane-spanning 4-domains subfamily A member 5; May be involved in signal transduction as a component of a multimeric receptor complex.	0.559
MS4A18	MS4A6A	ENSP00000431607	ENSP00000435844	Membrane spanning 4-domains A18.	Membrane-spanning 4-domains subfamily A member 6A; May be involved in signal transduction as a component of a multimeric receptor complex; Belongs to the MS4A family.	0.513
MS4A18	MS4A6E	ENSP00000431607	ENSP00000300182	Membrane spanning 4-domains A18.	Membrane-spanning 4-domains subfamily A member 6E; May be involved in signal transduction as a component of a multimeric receptor complex.	0.518
MS4A18	OOSP1	ENSP00000431607	ENSP00000494485	Membrane spanning 4-domains A18.	Putative oocyte-secreted protein 1 homolog; May be involved in cell differentiation; Belongs to the PLAC1 family.	0.424
MS4A18	OOSP2	ENSP00000431607	ENSP00000278855	Membrane spanning 4-domains A18.	Oocyte secreted protein 2.	0.598
MS4A18	TMEM176A	ENSP00000431607	ENSP00000417626	Membrane spanning 4-domains A18.	Transmembrane protein 176A.	0.649
MS4A18	TRPM5	ENSP00000431607	ENSP00000155858	Membrane spanning 4-domains A18.	Transient receptor potential cation channel subfamily M member 5; Voltage-modulated Ca(2+)-activated, monovalent cation channel (VCAM) that mediates a transient membrane depolarization and plays a central role in taste transduction. Monovalent-specific, non-selective cation channel that mediates the transport of Na(+), K(+) and Cs(+) ions equally well. Activated directly by increases in intracellular Ca(2+), but is impermeable to it. Gating is voltage-dependent and displays rapid activation and deactivation kinetics upon channel stimulation even during sustained elevations in Ca(2+). A [...]	0.453
MS4A5	MS4A10	ENSP00000300190	ENSP00000311862	Membrane-spanning 4-domains subfamily A member 5; May be involved in signal transduction as a component of a multimeric receptor complex.	Membrane-spanning 4-domains subfamily A member 10; May be involved in signal transduction as a component of a multimeric receptor complex; Belongs to the MS4A family.	0.679
MS4A5	MS4A18	ENSP00000300190	ENSP00000431607	Membrane-spanning 4-domains subfamily A member 5; May be involved in signal transduction as a component of a multimeric receptor complex.	Membrane spanning 4-domains A18.	0.559
MS4A5	MS4A6E	ENSP00000300190	ENSP00000300182	Membrane-spanning 4-domains subfamily A member 5; May be involved in signal transduction as a component of a multimeric receptor complex.	Membrane-spanning 4-domains subfamily A member 6E; May be involved in signal transduction as a component of a multimeric receptor complex.	0.699
MS4A5	OOSP2	ENSP00000300190	ENSP00000278855	Membrane-spanning 4-domains subfamily A member 5; May be involved in signal transduction as a component of a multimeric receptor complex.	Oocyte secreted protein 2.	0.670