C1orf94 protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASPHD1	C1orf94	ENSP00000311447	ENSP00000435634	Aspartate beta-hydroxylase domain containing 1.	Uncharacterized protein C1orf94; Chromosome 1 open reading frame 94.	0.464
ASPHD1	ZBTB8OS	ENSP00000311447	ENSP00000417677	Aspartate beta-hydroxylase domain containing 1.	Protein archease; Component of the tRNA-splicing ligase complex required to facilitate the enzymatic turnover of catalytic subunit RTCB. Together with DDX1, acts by facilitating the guanylylation of RTCB, a key intermediate step in tRNA ligation; Belongs to the archease family.	0.428
ATXN1	C1orf94	ENSP00000244769	ENSP00000435634	Ataxin-1; Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ- mediated repression. Binds RNA in vitro. May be involved in RNA metabolism. In concert with CIC and ATXN1L, involved in brain development (By similarity).	Uncharacterized protein C1orf94; Chromosome 1 open reading frame 94.	0.618
ATXN1	DAZAP2	ENSP00000244769	ENSP00000448051	Ataxin-1; Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ- mediated repression. Binds RNA in vitro. May be involved in RNA metabolism. In concert with CIC and ATXN1L, involved in brain development (By similarity).	DAZ associated protein 2.	0.493
C11orf94	C1orf94	ENSP00000401498	ENSP00000435634	Uncharacterized protein C11orf94; Chromosome 11 open reading frame 94.	Uncharacterized protein C1orf94; Chromosome 1 open reading frame 94.	0.455
C1orf94	ASPHD1	ENSP00000435634	ENSP00000311447	Uncharacterized protein C1orf94; Chromosome 1 open reading frame 94.	Aspartate beta-hydroxylase domain containing 1.	0.464
C1orf94	ATXN1	ENSP00000435634	ENSP00000244769	Uncharacterized protein C1orf94; Chromosome 1 open reading frame 94.	Ataxin-1; Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ- mediated repression. Binds RNA in vitro. May be involved in RNA metabolism. In concert with CIC and ATXN1L, involved in brain development (By similarity).	0.618
C1orf94	C11orf94	ENSP00000435634	ENSP00000401498	Uncharacterized protein C1orf94; Chromosome 1 open reading frame 94.	Uncharacterized protein C11orf94; Chromosome 11 open reading frame 94.	0.455
C1orf94	CCHCR1	ENSP00000435634	ENSP00000379566	Uncharacterized protein C1orf94; Chromosome 1 open reading frame 94.	Coiled-coil alpha-helical rod protein 1; May be a regulator of keratinocyte proliferation or differentiation.	0.816
C1orf94	DAZAP2	ENSP00000435634	ENSP00000448051	Uncharacterized protein C1orf94; Chromosome 1 open reading frame 94.	DAZ associated protein 2.	0.454
C1orf94	MAPK1IP1L	ENSP00000435634	ENSP00000378851	Uncharacterized protein C1orf94; Chromosome 1 open reading frame 94.	MAPK-interacting and spindle-stabilizing protein-like; Mitogen-activated protein kinase 1 interacting protein 1 like.	0.687
C1orf94	ROR2	ENSP00000435634	ENSP00000364860	Uncharacterized protein C1orf94; Chromosome 1 open reading frame 94.	Tyrosine-protein kinase transmembrane receptor ROR2; Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development (By similarity). Phosphorylates YWHAB, leading to induction of osteogenesis and bone formation. In contrast, has also been shown to have very little tyrosine kinase activity in vitro. May act as a receptor for wnt ligand WNT5A which may result in the inhibition of WNT3A-mediated signaling.	0.784
C1orf94	RPAP1	ENSP00000435634	ENSP00000306123	Uncharacterized protein C1orf94; Chromosome 1 open reading frame 94.	RNA polymerase II-associated protein 1; Forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding protein, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation. Required for interaction of the RNA polymerase II complex with acetylated histone H3; Belongs to the RPAP1 family.	0.760
C1orf94	USO1	ENSP00000435634	ENSP00000264904	Uncharacterized protein C1orf94; Chromosome 1 open reading frame 94.	General vesicular transport factor p115; General vesicular transport factor required for intercisternal transport in the Golgi stack; it is required for transcytotic fusion and/or subsequent binding of the vesicles to the target membrane. May well act as a vesicular anchor by interacting with the target membrane and holding the vesicular and target membranes in proximity.	0.531
C1orf94	ZBTB8OS	ENSP00000435634	ENSP00000417677	Uncharacterized protein C1orf94; Chromosome 1 open reading frame 94.	Protein archease; Component of the tRNA-splicing ligase complex required to facilitate the enzymatic turnover of catalytic subunit RTCB. Together with DDX1, acts by facilitating the guanylylation of RTCB, a key intermediate step in tRNA ligation; Belongs to the archease family.	0.595
CCHCR1	C1orf94	ENSP00000379566	ENSP00000435634	Coiled-coil alpha-helical rod protein 1; May be a regulator of keratinocyte proliferation or differentiation.	Uncharacterized protein C1orf94; Chromosome 1 open reading frame 94.	0.816
DAZAP2	ATXN1	ENSP00000448051	ENSP00000244769	DAZ associated protein 2.	Ataxin-1; Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ- mediated repression. Binds RNA in vitro. May be involved in RNA metabolism. In concert with CIC and ATXN1L, involved in brain development (By similarity).	0.493
DAZAP2	C1orf94	ENSP00000448051	ENSP00000435634	DAZ associated protein 2.	Uncharacterized protein C1orf94; Chromosome 1 open reading frame 94.	0.454
DAZAP2	MAPK1IP1L	ENSP00000448051	ENSP00000378851	DAZ associated protein 2.	MAPK-interacting and spindle-stabilizing protein-like; Mitogen-activated protein kinase 1 interacting protein 1 like.	0.589
DAZAP2	ROR2	ENSP00000448051	ENSP00000364860	DAZ associated protein 2.	Tyrosine-protein kinase transmembrane receptor ROR2; Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development (By similarity). Phosphorylates YWHAB, leading to induction of osteogenesis and bone formation. In contrast, has also been shown to have very little tyrosine kinase activity in vitro. May act as a receptor for wnt ligand WNT5A which may result in the inhibition of WNT3A-mediated signaling.	0.803