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ZNF707 protein (human) - STRING interaction network
"ZNF707" - Zinc finger protein 707 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZNF707Zinc finger protein 707; May be involved in transcriptional regulation; Zinc fingers C2H2-type (371 aa)    
Predicted Functional Partners:
TRIM28
Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at ’Lys-9’ (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 ’Lys-9 and ’Lys-14’ acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] (835 aa)
     
    0.911
MRPS31
Mitochondrial ribosomal protein S31 (395 aa)
       
      0.660
MRPS5
Mitochondrial ribosomal protein S5 (430 aa)
       
      0.644
KIAA1875
WD repeat-containing protein 97; KIAA1875 (1622 aa)
           
  0.587
LRRC14
Leucine-rich repeat-containing protein 14; Negatively regulates Toll-like receptor-mediated NF- kappa-B signaling by disrupting IKK core complex formation through interaction with IKBKB; Belongs to the PRAME family. LRRC14 subfamily (493 aa)
           
  0.578
ZNF273
Zinc finger protein 273; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family (569 aa)
       
   
0.561
ADCK5
Uncharacterized aarF domain-containing protein kinase 5; The function of this protein is not yet clear. It is not known if it has protein kinase activity and what type of substrate it would phosphorylate (Ser, Thr or Tyr) (580 aa)
           
  0.550
MRPS18C
Mitochondrial ribosomal protein S18C (142 aa)
       
      0.547
LRRC24
Leucine-rich repeat-containing protein 24; Leucine rich repeat containing 24; I-set domain containing (513 aa)
       
 
  0.539
MRPS2
Mitochondrial ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family (296 aa)
       
      0.536
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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