node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ARMC3 | CCDC189 | ENSP00000298032 | ENSP00000437532 | Armadillo repeat containing 3. | Coiled-coil domain containing 189. | 0.625 |
ARMC3 | TMEM95 | ENSP00000298032 | ENSP00000374632 | Armadillo repeat containing 3. | Transmembrane protein 95. | 0.665 |
CCDC189 | ARMC3 | ENSP00000437532 | ENSP00000298032 | Coiled-coil domain containing 189. | Armadillo repeat containing 3. | 0.625 |
CCDC189 | CFAP221 | ENSP00000437532 | ENSP00000393222 | Coiled-coil domain containing 189. | Cilia- and flagella-associated protein 221; May play a role in cilium morphogenesis. | 0.622 |
CCDC189 | CFAP74 | ENSP00000437532 | ENSP00000417061 | Coiled-coil domain containing 189. | Cilia- and flagella-associated protein 74; As part of the central apparatus of the cilium axoneme may play a role in cilium movement. | 0.572 |
CCDC189 | DPY30 | ENSP00000437532 | ENSP00000345837 | Coiled-coil domain containing 189. | Protein dpy-30 homolog; As part of the MLL1/MLL complex, involved in the methylation of histone H3 at 'Lys-4', particularly trimethylation. Histone H3 'Lys- 4' methylation represents a specific tag for epigenetic transcriptional activation. May play some role in histone H3 acetylation. In a teratocarcinoma cell, plays a crucial role in retinoic acid-induced differentiation along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci. May also play an indirect or direct role in endosomal transport. Belongs to the dpy-30 family. | 0.724 |
CCDC189 | LRGUK | ENSP00000437532 | ENSP00000285928 | Coiled-coil domain containing 189. | Leucine-rich repeat and guanylate kinase domain-containing protein; Involved in multiple aspects of sperm assembly including acrosome attachment, shaping of the sperm head and in the early aspects of axoneme development. Not essential for primary cilium biogenesis. | 0.861 |
CCDC189 | MYCBP | ENSP00000437532 | ENSP00000380702 | Coiled-coil domain containing 189. | c-Myc-binding protein; May control the transcriptional activity of MYC. Stimulates the activation of E box-dependent transcription by MYC. | 0.550 |
CCDC189 | PDZD9 | ENSP00000437532 | ENSP00000441685 | Coiled-coil domain containing 189. | PDZ domain containing 9. | 0.597 |
CCDC189 | PRSS36 | ENSP00000437532 | ENSP00000268281 | Coiled-coil domain containing 189. | Polyserase-2; Serine protease. Hydrolyzes the peptides N-t-Boc-Gln-Ala-Arg- AMC and N-t-Boc-Gln-Gly-Arg-AMC and, to a lesser extent, N-t-Boc-Ala- Phe-Lys-AMC and N-t-Boc-Val-Leu-Lys-AMC. Has a preference for substrates with an Arg instead of a Lys residue in position P1; Belongs to the peptidase S1 family. | 0.571 |
CCDC189 | SPAG17 | ENSP00000437532 | ENSP00000337804 | Coiled-coil domain containing 189. | Sperm-associated antigen 17; Component of the central pair apparatus of ciliary axonemes. Plays a critical role in the function and structure of motile cilia. May play a role in endochondral bone formation, most likely because of a function in primary cilia of chondrocytes and osteoblasts. | 0.697 |
CCDC189 | TMEM95 | ENSP00000437532 | ENSP00000374632 | Coiled-coil domain containing 189. | Transmembrane protein 95. | 0.706 |
CFAP221 | CCDC189 | ENSP00000393222 | ENSP00000437532 | Cilia- and flagella-associated protein 221; May play a role in cilium morphogenesis. | Coiled-coil domain containing 189. | 0.622 |
CFAP221 | CFAP74 | ENSP00000393222 | ENSP00000417061 | Cilia- and flagella-associated protein 221; May play a role in cilium morphogenesis. | Cilia- and flagella-associated protein 74; As part of the central apparatus of the cilium axoneme may play a role in cilium movement. | 0.818 |
CFAP221 | DPY30 | ENSP00000393222 | ENSP00000345837 | Cilia- and flagella-associated protein 221; May play a role in cilium morphogenesis. | Protein dpy-30 homolog; As part of the MLL1/MLL complex, involved in the methylation of histone H3 at 'Lys-4', particularly trimethylation. Histone H3 'Lys- 4' methylation represents a specific tag for epigenetic transcriptional activation. May play some role in histone H3 acetylation. In a teratocarcinoma cell, plays a crucial role in retinoic acid-induced differentiation along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci. May also play an indirect or direct role in endosomal transport. Belongs to the dpy-30 family. | 0.600 |
CFAP221 | LRGUK | ENSP00000393222 | ENSP00000285928 | Cilia- and flagella-associated protein 221; May play a role in cilium morphogenesis. | Leucine-rich repeat and guanylate kinase domain-containing protein; Involved in multiple aspects of sperm assembly including acrosome attachment, shaping of the sperm head and in the early aspects of axoneme development. Not essential for primary cilium biogenesis. | 0.849 |
CFAP221 | SPAG17 | ENSP00000393222 | ENSP00000337804 | Cilia- and flagella-associated protein 221; May play a role in cilium morphogenesis. | Sperm-associated antigen 17; Component of the central pair apparatus of ciliary axonemes. Plays a critical role in the function and structure of motile cilia. May play a role in endochondral bone formation, most likely because of a function in primary cilia of chondrocytes and osteoblasts. | 0.807 |
CFAP74 | CCDC189 | ENSP00000417061 | ENSP00000437532 | Cilia- and flagella-associated protein 74; As part of the central apparatus of the cilium axoneme may play a role in cilium movement. | Coiled-coil domain containing 189. | 0.572 |
CFAP74 | CFAP221 | ENSP00000417061 | ENSP00000393222 | Cilia- and flagella-associated protein 74; As part of the central apparatus of the cilium axoneme may play a role in cilium movement. | Cilia- and flagella-associated protein 221; May play a role in cilium morphogenesis. | 0.818 |
CFAP74 | DPY30 | ENSP00000417061 | ENSP00000345837 | Cilia- and flagella-associated protein 74; As part of the central apparatus of the cilium axoneme may play a role in cilium movement. | Protein dpy-30 homolog; As part of the MLL1/MLL complex, involved in the methylation of histone H3 at 'Lys-4', particularly trimethylation. Histone H3 'Lys- 4' methylation represents a specific tag for epigenetic transcriptional activation. May play some role in histone H3 acetylation. In a teratocarcinoma cell, plays a crucial role in retinoic acid-induced differentiation along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci. May also play an indirect or direct role in endosomal transport. Belongs to the dpy-30 family. | 0.515 |