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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PPIAL4DPeptidyl-prolyl cis-trans isomerase A-like 4D; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity); Belongs to the cyclophilin-type PPIase family. PPIase A subfamily. (164 aa)    
Predicted Functional Partners:
RANBP1
Ran-specific GTPase-activating protein; Plays a role in RAN-dependent nucleocytoplasmic transport. Alleviates the TNPO1-dependent inhibition of RAN GTPase activity and mediates the dissociation of RAN from proteins involved in transport into the nucleus (By similarity). Induces a conformation change in the complex formed by XPO1 and RAN that triggers the release of the nuclear export signal of cargo proteins. Promotes the disassembly of the complex formed by RAN and importin beta. Promotes dissociation of RAN from a complex with KPNA2 and CSE1L (By similarity). Required for normal mito [...]
 
 
 
 0.723
SPATA31A5
Spermatogenesis-associated protein 31A5; May play a role in spermatogenesis; Belongs to the SPATA31 family.
      
 0.720
TRIM64B
Putative tripartite motif-containing protein 64B; Tripartite motif containing 64B; Belongs to the TRIM/RBCC family.
      
 0.604
RGPD3
RANBP2 like and GRIP domain containing 3.
 
 
 
 0.598
RGPD5
RANBP2-like and GRIP domain-containing protein 5/6; RANBP2 like and GRIP domain containing 5.
 
 
 
 0.593
RGPD6
RANBP2 like and GRIP domain containing 6.
 
 
 
 0.593
FAM131C
Protein FAM131C; Family with sequence similarity 131 member C.
      
 0.570
RGPD4
RANBP2 like and GRIP domain containing 4.
 
      0.540
RGPD2
RANBP2 like and GRIP domain containing 2.
 
      0.536
RGPD8
RANBP2 like and GRIP domain containing 8.
 
      0.535
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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