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ZNF185 protein (human) - STRING interaction network
"ZNF185" - Zinc finger protein 185 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ZNF185Zinc finger protein 185; May be involved in the regulation of cellular proliferation and/or differentiation; LIM domain containing (721 aa)    
Predicted Functional Partners:
EVPL
Envoplakin; Component of the cornified envelope of keratinocytes. May link the cornified envelope to desmosomes and intermediate filaments; Plakins (2033 aa)
     
 
  0.879
TFF3
Trefoil factor 3; Involved in the maintenance and repair of the intestinal mucosa. Promotes the mobility of epithelial cells in healing processes (motogen) (94 aa)
           
  0.863
AHNAK
Neuroblast differentiation-associated protein AHNAK; May be required for neuronal cell differentiation; PDZ domain containing (5890 aa)
     
   
  0.837
PPL
Periplakin; Component of the cornified envelope of keratinocytes. May link the cornified envelope to desmosomes and intermediate filaments. May act as a localization signal in PKB/AKT-mediated signaling; Belongs to the plakin or cytolinker family (1756 aa)
     
 
  0.817
CAPN9
Calpain-9; Calcium-regulated non-lysosomal thiol-protease; Belongs to the peptidase C2 family (690 aa)
     
 
  0.738
TMEM234
Transmembrane protein 234 (140 aa)
           
  0.721
IFI27
Interferon alpha-inducible protein 27, mitochondrial; Promotes cell death. Mediates IFN-induced apoptosis characterized by a rapid and robust release of cytochrome C from the mitochondria and activation of BAX and caspases 2, 3, 6, 8 and 9 (122 aa)
           
  0.544
CYP3A4
Cytochrome P450 3A4; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It performs a variety of oxidation reactions (e.g. caffeine 8-oxidation, omeprazole sulphoxidation, midazolam 1’-hydroxylation and midazolam 4- hydroxylation) of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Acts as a 1,8-cineole 2- exo-monooxygenase. The enzyme also hydroxylates etoposide. Catalyzes 4-beta-hydroxylation of cholesterol. May catalyze 25-hydroxylation of chol [...] (503 aa)
           
  0.542
GAS2
Growth arrest-specific protein 2; May play a role in apoptosis by acting as a cell death substrate for caspases. Is cleaved during apoptosis and the cleaved form induces dramatic rearrangements of the actin cytoskeleton and potent changes in the shape of the affected cells. May be involved in the membrane ruffling process (By similarity) (313 aa)
     
 
  0.519
RFTN2
Raftlin-2; Raftlin family member 2; Belongs to the raftlin family (501 aa)
           
  0.517
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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