node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DSG4 | KRT33B | ENSP00000352785 | ENSP00000251646 | Desmoglein-4; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. Coordinates the transition from proliferation to differentiation in hair follicle keratinocytes (By similarity). | Keratin, type I cuticular Ha3-II; Keratin 33B; Belongs to the intermediate filament family. | 0.625 |
DSG4 | KRT71 | ENSP00000352785 | ENSP00000267119 | Desmoglein-4; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. Coordinates the transition from proliferation to differentiation in hair follicle keratinocytes (By similarity). | Keratin, type II cytoskeletal 71; Plays a central role in hair formation. Essential component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle. | 0.571 |
DSG4 | KRT81 | ENSP00000352785 | ENSP00000369349 | Desmoglein-4; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. Coordinates the transition from proliferation to differentiation in hair follicle keratinocytes (By similarity). | Keratin, type II cuticular Hb1; Keratin 81. | 0.756 |
DSG4 | KRT83 | ENSP00000352785 | ENSP00000293670 | Desmoglein-4; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. Coordinates the transition from proliferation to differentiation in hair follicle keratinocytes (By similarity). | Keratin, type II cuticular Hb3; Keratin 83; Belongs to the intermediate filament family. | 0.913 |
DSG4 | KRT85 | ENSP00000352785 | ENSP00000257901 | Desmoglein-4; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. Coordinates the transition from proliferation to differentiation in hair follicle keratinocytes (By similarity). | Keratin, type II cuticular Hb5; Keratin 85; Belongs to the intermediate filament family. | 0.447 |
DSG4 | KRT86 | ENSP00000352785 | ENSP00000444533 | Desmoglein-4; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. Coordinates the transition from proliferation to differentiation in hair follicle keratinocytes (By similarity). | Keratin, type II cuticular Hb6. | 0.885 |
DSG4 | KRTAP3-1 | ENSP00000352785 | ENSP00000375430 | Desmoglein-4; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. Coordinates the transition from proliferation to differentiation in hair follicle keratinocytes (By similarity). | Keratin-associated protein 3-1; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins. | 0.665 |
KRT33B | DSG4 | ENSP00000251646 | ENSP00000352785 | Keratin, type I cuticular Ha3-II; Keratin 33B; Belongs to the intermediate filament family. | Desmoglein-4; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. Coordinates the transition from proliferation to differentiation in hair follicle keratinocytes (By similarity). | 0.625 |
KRT33B | KRT39 | ENSP00000251646 | ENSP00000347823 | Keratin, type I cuticular Ha3-II; Keratin 33B; Belongs to the intermediate filament family. | Keratin, type I cytoskeletal 39; May play a role in late hair differentiation. | 0.420 |
KRT33B | KRT71 | ENSP00000251646 | ENSP00000267119 | Keratin, type I cuticular Ha3-II; Keratin 33B; Belongs to the intermediate filament family. | Keratin, type II cytoskeletal 71; Plays a central role in hair formation. Essential component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle. | 0.629 |
KRT33B | KRT81 | ENSP00000251646 | ENSP00000369349 | Keratin, type I cuticular Ha3-II; Keratin 33B; Belongs to the intermediate filament family. | Keratin, type II cuticular Hb1; Keratin 81. | 0.421 |
KRT33B | KRT83 | ENSP00000251646 | ENSP00000293670 | Keratin, type I cuticular Ha3-II; Keratin 33B; Belongs to the intermediate filament family. | Keratin, type II cuticular Hb3; Keratin 83; Belongs to the intermediate filament family. | 0.641 |
KRT33B | KRT85 | ENSP00000251646 | ENSP00000257901 | Keratin, type I cuticular Ha3-II; Keratin 33B; Belongs to the intermediate filament family. | Keratin, type II cuticular Hb5; Keratin 85; Belongs to the intermediate filament family. | 0.603 |
KRT33B | KRT86 | ENSP00000251646 | ENSP00000444533 | Keratin, type I cuticular Ha3-II; Keratin 33B; Belongs to the intermediate filament family. | Keratin, type II cuticular Hb6. | 0.602 |
KRT33B | KRTAP3-1 | ENSP00000251646 | ENSP00000375430 | Keratin, type I cuticular Ha3-II; Keratin 33B; Belongs to the intermediate filament family. | Keratin-associated protein 3-1; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins. | 0.878 |
KRT39 | KRT33B | ENSP00000347823 | ENSP00000251646 | Keratin, type I cytoskeletal 39; May play a role in late hair differentiation. | Keratin, type I cuticular Ha3-II; Keratin 33B; Belongs to the intermediate filament family. | 0.420 |
KRT39 | KRT86 | ENSP00000347823 | ENSP00000444533 | Keratin, type I cytoskeletal 39; May play a role in late hair differentiation. | Keratin, type II cuticular Hb6. | 0.662 |
KRT39 | KRTAP3-1 | ENSP00000347823 | ENSP00000375430 | Keratin, type I cytoskeletal 39; May play a role in late hair differentiation. | Keratin-associated protein 3-1; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins. | 0.491 |
KRT71 | DSG4 | ENSP00000267119 | ENSP00000352785 | Keratin, type II cytoskeletal 71; Plays a central role in hair formation. Essential component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle. | Desmoglein-4; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. Coordinates the transition from proliferation to differentiation in hair follicle keratinocytes (By similarity). | 0.571 |
KRT71 | KRT33B | ENSP00000267119 | ENSP00000251646 | Keratin, type II cytoskeletal 71; Plays a central role in hair formation. Essential component of keratin intermediate filaments in the inner root sheath (IRS) of the hair follicle. | Keratin, type I cuticular Ha3-II; Keratin 33B; Belongs to the intermediate filament family. | 0.629 |