STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GLB1L2Beta-galactosidase-1-like protein 2; Galactosidase beta 1 like 2. (636 aa)    
Predicted Functional Partners:
PATE3
Prostate and testis expressed 3; Belongs to the PATE family.
      
 0.595
PATE2
Prostate and testis expressed 2.
      
 0.560
PATE1
Prostate and testis expressed 1; Belongs to the PATE family.
   
  
 0.543
PRR32
Proline-rich protein 32; Proline rich 32.
   
  
 0.502
DEFB115
Beta-defensin 115; Has antibacterial activity; Belongs to the beta-defensin family.
      
 0.481
CLPSL2
Colipase-like protein 2; Colipase like 2.
      
 0.447
GOLPH3L
Golgi phosphoprotein 3-like; Phosphatidylinositol-4-phosphate-binding protein that may antagonize the action of GOLPH3 which is required for the process of vesicle budding at the Golgi and anterograde transport to the plasma membrane.
    
   0.433
LRRC23
Leucine-rich repeat-containing protein 23; Leucine rich repeat containing 23.
   
  
 0.427
ZNF431
Zinc finger protein 431; Sequence-specific DNA binding transcriptional repressor. Represses target gene transcription by recruiting HDAC1 and HDAC2 histone deacetylases. Acts as a specific transcriptional repressor for PTCH1 during embryonic development. Required for osteoblast differentiation and sonic hedgehog/SHH signaling response. Binds to the consensus site 5'-GCGCCC-3' in the promoter of PTCH1 (By similarity). Belongs to the krueppel C2H2-type zinc-finger protein family.
   
  
 0.425
AFAP1L1
Actin filament-associated protein 1-like 1; May be involved in podosome and invadosome formation.
   
  
 0.424
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.