C21orf62 protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C12orf56	C21orf62	ENSP00000446101	ENSP00000418653	Uncharacterized protein C12orf56; Chromosome 12 open reading frame 56.	Uncharacterized protein C21orf62; Chromosome 21 open reading frame 62.	0.440
C12orf56	C22orf42	ENSP00000446101	ENSP00000371529	Uncharacterized protein C12orf56; Chromosome 12 open reading frame 56.	Uncharacterized protein C22orf42; Chromosome 22 open reading frame 42.	0.470
C12orf56	C3orf22	ENSP00000446101	ENSP00000316644	Uncharacterized protein C12orf56; Chromosome 12 open reading frame 56.	Uncharacterized protein C3orf22; Chromosome 3 open reading frame 22.	0.570
C12orf56	SH2D7	ENSP00000446101	ENSP00000327846	Uncharacterized protein C12orf56; Chromosome 12 open reading frame 56.	SH2 domain containing 7.	0.500
C12orf56	SMIM17	ENSP00000446101	ENSP00000471126	Uncharacterized protein C12orf56; Chromosome 12 open reading frame 56.	Small integral membrane protein 17.	0.536
C21orf62	C12orf56	ENSP00000418653	ENSP00000446101	Uncharacterized protein C21orf62; Chromosome 21 open reading frame 62.	Uncharacterized protein C12orf56; Chromosome 12 open reading frame 56.	0.440
C21orf62	C22orf15	ENSP00000418653	ENSP00000305096	Uncharacterized protein C21orf62; Chromosome 21 open reading frame 62.	Uncharacterized protein C22orf15; Chromosome 22 open reading frame 15.	0.430
C21orf62	C22orf42	ENSP00000418653	ENSP00000371529	Uncharacterized protein C21orf62; Chromosome 21 open reading frame 62.	Uncharacterized protein C22orf42; Chromosome 22 open reading frame 42.	0.435
C21orf62	C3orf22	ENSP00000418653	ENSP00000316644	Uncharacterized protein C21orf62; Chromosome 21 open reading frame 62.	Uncharacterized protein C3orf22; Chromosome 3 open reading frame 22.	0.470
C21orf62	FAM149B1	ENSP00000418653	ENSP00000242505	Uncharacterized protein C21orf62; Chromosome 21 open reading frame 62.	Protein FAM149B1; Family with sequence similarity 149 member B1.	0.435
C21orf62	ITPRID2	ENSP00000418653	ENSP00000388731	Uncharacterized protein C21orf62; Chromosome 21 open reading frame 62.	Protein ITPRID2; ITPR interacting domain containing 2.	0.430
C21orf62	PKD1	ENSP00000418653	ENSP00000262304	Uncharacterized protein C21orf62; Chromosome 21 open reading frame 62.	Polycystin-1; Component of a heteromeric calcium-permeable ion channel formed by PKD1 and PKD2 that is activated by interaction between PKD1 and a Wnt family member, such as WNT3A and WNT9B. Both PKD1 and PKD2 are required for channel activity. Involved in renal tubulogenesis. Involved in fluid- flow mechanosensation by the primary cilium in renal epithelium (By similarity). Acts as a regulator of cilium length, together with PKD2 (By similarity). The dynamic control of cilium length is essential in the regulation of mechanotransductive signaling (By similarity). The cilium length resp [...]	0.496
C21orf62	PTCD2	ENSP00000418653	ENSP00000370013	Uncharacterized protein C21orf62; Chromosome 21 open reading frame 62.	Pentatricopeptide repeat-containing protein 2, mitochondrial; Involved in mitochondrial RNA maturation and mitochondrial respiratory chain function.	0.420
C21orf62	SH2D7	ENSP00000418653	ENSP00000327846	Uncharacterized protein C21orf62; Chromosome 21 open reading frame 62.	SH2 domain containing 7.	0.408
C21orf62	SMIM17	ENSP00000418653	ENSP00000471126	Uncharacterized protein C21orf62; Chromosome 21 open reading frame 62.	Small integral membrane protein 17.	0.436
C22orf15	C21orf62	ENSP00000305096	ENSP00000418653	Uncharacterized protein C22orf15; Chromosome 22 open reading frame 15.	Uncharacterized protein C21orf62; Chromosome 21 open reading frame 62.	0.430
C22orf42	C12orf56	ENSP00000371529	ENSP00000446101	Uncharacterized protein C22orf42; Chromosome 22 open reading frame 42.	Uncharacterized protein C12orf56; Chromosome 12 open reading frame 56.	0.470
C22orf42	C21orf62	ENSP00000371529	ENSP00000418653	Uncharacterized protein C22orf42; Chromosome 22 open reading frame 42.	Uncharacterized protein C21orf62; Chromosome 21 open reading frame 62.	0.435
C22orf42	C3orf22	ENSP00000371529	ENSP00000316644	Uncharacterized protein C22orf42; Chromosome 22 open reading frame 42.	Uncharacterized protein C3orf22; Chromosome 3 open reading frame 22.	0.499
C22orf42	SH2D7	ENSP00000371529	ENSP00000327846	Uncharacterized protein C22orf42; Chromosome 22 open reading frame 42.	SH2 domain containing 7.	0.441