node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CALHM3 | GCSAML | ENSP00000358798 | ENSP00000446460 | Calcium homeostasis modulator protein 3; Pore-forming subunit of a voltage-gated ion channel, also permeable to larger molecules including ATP. Together with CALHM1, forms a fast-activating voltage-gated ATP-release channel in type II taste bud cells (TBCs). CALHM1-CALHM3-mediated ATP released acts as a neurotransmitter to gustatory neurons in response to GPCR-mediated tastes, including sweet, bitter and umami substances. | Germinal center associated signaling and motility like. | 0.476 |
DHRS13 | GCSAML | ENSP00000368173 | ENSP00000446460 | Dehydrogenase/reductase SDR family member 13; Putative oxidoreductase. | Germinal center associated signaling and motility like. | 0.413 |
GCSAML | CALHM3 | ENSP00000446460 | ENSP00000358798 | Germinal center associated signaling and motility like. | Calcium homeostasis modulator protein 3; Pore-forming subunit of a voltage-gated ion channel, also permeable to larger molecules including ATP. Together with CALHM1, forms a fast-activating voltage-gated ATP-release channel in type II taste bud cells (TBCs). CALHM1-CALHM3-mediated ATP released acts as a neurotransmitter to gustatory neurons in response to GPCR-mediated tastes, including sweet, bitter and umami substances. | 0.476 |
GCSAML | DHRS13 | ENSP00000446460 | ENSP00000368173 | Germinal center associated signaling and motility like. | Dehydrogenase/reductase SDR family member 13; Putative oxidoreductase. | 0.413 |
GCSAML | GCSAML-AS1 | ENSP00000446460 | ENSP00000479757 | Germinal center associated signaling and motility like. | Olfactory receptor 2C3; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | 0.432 |
GCSAML | MTMR8 | ENSP00000446460 | ENSP00000363985 | Germinal center associated signaling and motility like. | Myotubularin-related protein 8; Phosphatase that acts on lipids with a phosphoinositol headgroup. Has phosphatase activity towards phosphatidylinositol 3-phosphate and phosphatidylinositol 3,5- bisphosphate. In complex with MTMR9, negatively regulates autophagy. | 0.438 |
GCSAML | PTPRE | ENSP00000446460 | ENSP00000254667 | Germinal center associated signaling and motility like. | Receptor-type tyrosine-protein phosphatase epsilon; Isoform 1 plays a critical role in signaling transduction pathways and phosphoprotein network topology in red blood cells. May play a role in osteoclast formation and function (By similarity). Isoform 1 and isoform 2 act as a negative regulator of FceRI- mediated signal transduction leading to cytokine production and degranulation, most likely by acting at the level of SYK to affect downstream events such as phosphorylation of SLP76 and LAT and mobilization of Ca(2+); Belongs to the protein-tyrosine phosphatase family. Receptor class [...] | 0.417 |
GCSAML | SAMD12 | ENSP00000446460 | ENSP00000314173 | Germinal center associated signaling and motility like. | Sterile alpha motif domain containing 12. | 0.490 |
GCSAML | SEZ6L | ENSP00000446460 | ENSP00000248933 | Germinal center associated signaling and motility like. | Seizure 6-like protein; May contribute to specialized endoplasmic reticulum functions in neurons. | 0.531 |
GCSAML | USH1C | ENSP00000446460 | ENSP00000005226 | Germinal center associated signaling and motility like. | Harmonin; USH1 protein network component harmonin. | 0.419 |
GCSAML | ZNF71 | ENSP00000446460 | ENSP00000328245 | Germinal center associated signaling and motility like. | Endothelial zinc finger protein induced by tumor necrosis factor alpha; May be involved in transcriptional regulation. | 0.428 |
GCSAML-AS1 | GCSAML | ENSP00000479757 | ENSP00000446460 | Olfactory receptor 2C3; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | Germinal center associated signaling and motility like. | 0.432 |
MTMR8 | GCSAML | ENSP00000363985 | ENSP00000446460 | Myotubularin-related protein 8; Phosphatase that acts on lipids with a phosphoinositol headgroup. Has phosphatase activity towards phosphatidylinositol 3-phosphate and phosphatidylinositol 3,5- bisphosphate. In complex with MTMR9, negatively regulates autophagy. | Germinal center associated signaling and motility like. | 0.438 |
MTMR8 | ZNF71 | ENSP00000363985 | ENSP00000328245 | Myotubularin-related protein 8; Phosphatase that acts on lipids with a phosphoinositol headgroup. Has phosphatase activity towards phosphatidylinositol 3-phosphate and phosphatidylinositol 3,5- bisphosphate. In complex with MTMR9, negatively regulates autophagy. | Endothelial zinc finger protein induced by tumor necrosis factor alpha; May be involved in transcriptional regulation. | 0.465 |
PTPRE | GCSAML | ENSP00000254667 | ENSP00000446460 | Receptor-type tyrosine-protein phosphatase epsilon; Isoform 1 plays a critical role in signaling transduction pathways and phosphoprotein network topology in red blood cells. May play a role in osteoclast formation and function (By similarity). Isoform 1 and isoform 2 act as a negative regulator of FceRI- mediated signal transduction leading to cytokine production and degranulation, most likely by acting at the level of SYK to affect downstream events such as phosphorylation of SLP76 and LAT and mobilization of Ca(2+); Belongs to the protein-tyrosine phosphatase family. Receptor class [...] | Germinal center associated signaling and motility like. | 0.417 |
SAMD12 | GCSAML | ENSP00000314173 | ENSP00000446460 | Sterile alpha motif domain containing 12. | Germinal center associated signaling and motility like. | 0.490 |
SEZ6L | GCSAML | ENSP00000248933 | ENSP00000446460 | Seizure 6-like protein; May contribute to specialized endoplasmic reticulum functions in neurons. | Germinal center associated signaling and motility like. | 0.531 |
USH1C | GCSAML | ENSP00000005226 | ENSP00000446460 | Harmonin; USH1 protein network component harmonin. | Germinal center associated signaling and motility like. | 0.419 |
ZNF71 | GCSAML | ENSP00000328245 | ENSP00000446460 | Endothelial zinc finger protein induced by tumor necrosis factor alpha; May be involved in transcriptional regulation. | Germinal center associated signaling and motility like. | 0.428 |
ZNF71 | MTMR8 | ENSP00000328245 | ENSP00000363985 | Endothelial zinc finger protein induced by tumor necrosis factor alpha; May be involved in transcriptional regulation. | Myotubularin-related protein 8; Phosphatase that acts on lipids with a phosphoinositol headgroup. Has phosphatase activity towards phosphatidylinositol 3-phosphate and phosphatidylinositol 3,5- bisphosphate. In complex with MTMR9, negatively regulates autophagy. | 0.465 |