Calcium homeostasis modulator protein 3; Pore-forming subunit of a voltage-gated ion channel, also permeable to larger molecules including ATP. Together with CALHM1, forms a fast-activating voltage-gated ATP-release channel in type II taste bud cells (TBCs). CALHM1-CALHM3-mediated ATP released acts as a neurotransmitter to gustatory neurons in response to GPCR-mediated tastes, including sweet, bitter and umami substances.

Germinal center associated signaling and motility like.

Germinal center associated signaling and motility like.

Calcium homeostasis modulator protein 3; Pore-forming subunit of a voltage-gated ion channel, also permeable to larger molecules including ATP. Together with CALHM1, forms a fast-activating voltage-gated ATP-release channel in type II taste bud cells (TBCs). CALHM1-CALHM3-mediated ATP released acts as a neurotransmitter to gustatory neurons in response to GPCR-mediated tastes, including sweet, bitter and umami substances.

Germinal center associated signaling and motility like.

Olfactory receptor 2C3; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.

Germinal center associated signaling and motility like.

High affinity immunoglobulin epsilon receptor subunit beta; High affinity receptor that binds to the Fc region of immunoglobulins epsilon. Aggregation of FCER1 by multivalent antigens is required for the full mast cell response, including the release of preformed mediators (such as histamine) by degranulation and de novo production of lipid mediators and cytokines. Also mediates the secretion of important lymphokines. Binding of allergen to receptor- bound IgE leads to cell activation and the release of mediators responsible for the manifestations of allergy; Belongs to the MS4A family.

Germinal center associated signaling and motility like.

Myotubularin-related protein 8; Phosphatase that acts on lipids with a phosphoinositol headgroup. Has phosphatase activity towards phosphatidylinositol 3-phosphate and phosphatidylinositol 3,5- bisphosphate. In complex with MTMR9, negatively regulates autophagy.

Germinal center associated signaling and motility like.

Regulator of hemoglobinization and erythroid cell expansion protein; Acts as a signaling transduction factor of the EPO-EPOR signaling pathway promoting erythroid cell differentiation.

Germinal center associated signaling and motility like.

Sterile alpha motif domain containing 12.

Germinal center associated signaling and motility like.

Seizure 6-like protein; May contribute to specialized endoplasmic reticulum functions in neurons.

Germinal center associated signaling and motility like.

Protein O-mannosyl-transferase TMTC2; Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. The 4 members of the TMTC family are O-mannosyl- transferases dedicated primarily to the cadherin superfamily, each member seems to have a distinct role in decorating the cadherin domains with O-linked mannose glycans at specific regions. Also acts as O- mannosyl-transferase on other proteins such as PDIA3.

Germinal center associated signaling and motility like.

WD repeat domain 27.

Germinal center associated signaling and motility like.

Endothelial zinc finger protein induced by tumor necrosis factor alpha; May be involved in transcriptional regulation.

Olfactory receptor 2C3; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.

Germinal center associated signaling and motility like.

High affinity immunoglobulin epsilon receptor subunit beta; High affinity receptor that binds to the Fc region of immunoglobulins epsilon. Aggregation of FCER1 by multivalent antigens is required for the full mast cell response, including the release of preformed mediators (such as histamine) by degranulation and de novo production of lipid mediators and cytokines. Also mediates the secretion of important lymphokines. Binding of allergen to receptor- bound IgE leads to cell activation and the release of mediators responsible for the manifestations of allergy; Belongs to the MS4A family.

Germinal center associated signaling and motility like.

Myotubularin-related protein 8; Phosphatase that acts on lipids with a phosphoinositol headgroup. Has phosphatase activity towards phosphatidylinositol 3-phosphate and phosphatidylinositol 3,5- bisphosphate. In complex with MTMR9, negatively regulates autophagy.

Germinal center associated signaling and motility like.

Myotubularin-related protein 8; Phosphatase that acts on lipids with a phosphoinositol headgroup. Has phosphatase activity towards phosphatidylinositol 3-phosphate and phosphatidylinositol 3,5- bisphosphate. In complex with MTMR9, negatively regulates autophagy.

Endothelial zinc finger protein induced by tumor necrosis factor alpha; May be involved in transcriptional regulation.

Regulator of hemoglobinization and erythroid cell expansion protein; Acts as a signaling transduction factor of the EPO-EPOR signaling pathway promoting erythroid cell differentiation.

Germinal center associated signaling and motility like.

Sterile alpha motif domain containing 12.

Germinal center associated signaling and motility like.

Seizure 6-like protein; May contribute to specialized endoplasmic reticulum functions in neurons.

Germinal center associated signaling and motility like.

Protein O-mannosyl-transferase TMTC2; Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. The 4 members of the TMTC family are O-mannosyl- transferases dedicated primarily to the cadherin superfamily, each member seems to have a distinct role in decorating the cadherin domains with O-linked mannose glycans at specific regions. Also acts as O- mannosyl-transferase on other proteins such as PDIA3.

Germinal center associated signaling and motility like.

WD repeat domain 27.

Germinal center associated signaling and motility like.