NPIPA2 protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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same PNG format, but at higher resolution

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SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NPIPA1	NPIPA2	ENSP00000331843	ENSP00000446882	Nuclear pore complex interacting protein family member A1.	Nuclear pore complex interacting protein family member A2; Belongs to the NPIP family.	0.943
NPIPA1	NPIPA3	ENSP00000331843	ENSP00000448841	Nuclear pore complex interacting protein family member A1.	Nuclear pore complex interacting protein family member A3.	0.941
NPIPA1	NPIPA5	ENSP00000331843	ENSP00000433597	Nuclear pore complex interacting protein family member A1.	Nuclear pore complex interacting protein family member A5.	0.943
NPIPA1	NPIPA8	ENSP00000331843	ENSP00000435325	Nuclear pore complex interacting protein family member A1.	Nuclear pore complex interacting protein family member A8.	0.942
NPIPA1	NPIPB11	ENSP00000331843	ENSP00000430853	Nuclear pore complex interacting protein family member A1.	Nuclear pore complex interacting protein family member B11.	0.725
NPIPA1	NPIPB2	ENSP00000331843	ENSP00000382101	Nuclear pore complex interacting protein family member A1.	Nuclear pore complex interacting protein family member B2.	0.846
NPIPA1	NPIPB4	ENSP00000331843	ENSP00000404439	Nuclear pore complex interacting protein family member A1.	Nuclear pore complex interacting protein family member B4.	0.492
NPIPA2	NPIPA1	ENSP00000446882	ENSP00000331843	Nuclear pore complex interacting protein family member A2; Belongs to the NPIP family.	Nuclear pore complex interacting protein family member A1.	0.943
NPIPA2	NPIPA3	ENSP00000446882	ENSP00000448841	Nuclear pore complex interacting protein family member A2; Belongs to the NPIP family.	Nuclear pore complex interacting protein family member A3.	0.945
NPIPA2	NPIPA5	ENSP00000446882	ENSP00000433597	Nuclear pore complex interacting protein family member A2; Belongs to the NPIP family.	Nuclear pore complex interacting protein family member A5.	0.941
NPIPA2	NPIPA8	ENSP00000446882	ENSP00000435325	Nuclear pore complex interacting protein family member A2; Belongs to the NPIP family.	Nuclear pore complex interacting protein family member A8.	0.941
NPIPA2	NPIPB11	ENSP00000446882	ENSP00000430853	Nuclear pore complex interacting protein family member A2; Belongs to the NPIP family.	Nuclear pore complex interacting protein family member B11.	0.718
NPIPA2	NPIPB2	ENSP00000446882	ENSP00000382101	Nuclear pore complex interacting protein family member A2; Belongs to the NPIP family.	Nuclear pore complex interacting protein family member B2.	0.730
NPIPA2	NPIPB4	ENSP00000446882	ENSP00000404439	Nuclear pore complex interacting protein family member A2; Belongs to the NPIP family.	Nuclear pore complex interacting protein family member B4.	0.500
NPIPA2	PDXDC1	ENSP00000446882	ENSP00000379691	Nuclear pore complex interacting protein family member A2; Belongs to the NPIP family.	Pyridoxal-dependent decarboxylase domain-containing protein 1; Pyridoxal dependent decarboxylase domain containing 1; Belongs to the group II decarboxylase family.	0.494
NPIPA2	STIMATE-MUSTN1	ENSP00000446882	ENSP00000422941	Nuclear pore complex interacting protein family member A2; Belongs to the NPIP family.	STIMATE-MUSTN1 readthrough.	0.448
NPIPA2	USP2	ENSP00000446882	ENSP00000260187	Nuclear pore complex interacting protein family member A2; Belongs to the NPIP family.	Ubiquitin carboxyl-terminal hydrolase 2; Hydrolase that deubiquitinates polyubiquitinated target proteins such as MDM2, MDM4 and CCND1. Isoform 1 and isoform 4 possess both ubiquitin-specific peptidase and isopeptidase activities (By similarity). Deubiquitinates MDM2 without reversing MDM2-mediated p53/TP53 ubiquitination and thus indirectly promotes p53/TP53 degradation and limits p53 activity. Has no deubiquitinase activity against p53/TP53. Prevents MDM2-mediated degradation of MDM4. Plays a role in the G1/S cell-cycle progression in normal and cancer cells. Regulates the circadian [...]	0.523
NPIPA3	NPIPA1	ENSP00000448841	ENSP00000331843	Nuclear pore complex interacting protein family member A3.	Nuclear pore complex interacting protein family member A1.	0.941
NPIPA3	NPIPA2	ENSP00000448841	ENSP00000446882	Nuclear pore complex interacting protein family member A3.	Nuclear pore complex interacting protein family member A2; Belongs to the NPIP family.	0.945
NPIPA3	NPIPA5	ENSP00000448841	ENSP00000433597	Nuclear pore complex interacting protein family member A3.	Nuclear pore complex interacting protein family member A5.	0.942