STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NPIPA2Nuclear pore complex interacting protein family member A2; Belongs to the NPIP family. (350 aa)    
Predicted Functional Partners:
GOLGA6B
Golgin A6 family member B; Belongs to the GOLGA6 family.
   
 
 0.557
PDXDC1
Pyridoxal-dependent decarboxylase domain-containing protein 1; Pyridoxal dependent decarboxylase domain containing 1; Belongs to the group II decarboxylase family.
      
 0.479
LRRC37A3
Leucine-rich repeat-containing protein 37A3; Leucine rich repeat containing 37 member A3.
    
 
 0.476
SMCO3
Single-pass membrane protein with coiled-coil domains 3.
      
 0.469
TBC1D3C
TBC1 domain family member 3C.
    
 
 0.453
NUP62
Nuclear pore glycoprotein p62; Essential component of the nuclear pore complex. The N-terminal is probably involved in nucleocytoplasmic transport. The C-terminal is involved in protein-protein interaction probably via coiled-coil formation, promotes its association with centrosomes and may function in anchorage of p62 to the pore complex. Plays a role in mitotic cell cycle progression by regulating centrosome segregation, centriole maturation and spindle orientation. It might be involved in protein recruitment to the centrosome after nuclear breakdown.
      
 0.438
LRRC37A
Leucine-rich repeat-containing protein 37A; Leucine rich repeat containing 37A.
    
 
 0.411
OR1J4
Olfactory receptor 1J4; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
    
 
 0.409
NBPF4
Neuroblastoma breakpoint family member 4; NBPF member 4.
   
 
 0.408
FOPNL
LisH domain-containing protein FOPNL; Involved in the biogenesis of cilia. Required for the recruitment of PLK1 to centrosomes and S phase progression.
   
  
 0.408
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.