STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NPIPB9Nuclear pore complex interacting protein family member B9; Belongs to the NPIP family. (429 aa)    
Predicted Functional Partners:
FAM25G
Family with sequence similarity 25 member G.
      
 0.664
OR10H5
Olfactory receptor 10H5; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
    
 
 0.578
FAM229B
Protein FAM229B; Family with sequence similarity 229 member B; Belongs to the FAM229 family.
      
 0.571
RABEP2
Rab GTPase-binding effector protein 2; Plays a role in membrane trafficking and in homotypic early endosome fusion. Participates in arteriogenesis by regulating vascular endothelial growth factor receptor 2/VEGFR2 cell surface expression and endosomal trafficking. By interacting with SDCCAG8, localizes to centrosomes and plays a critical role in ciliogenesis ; Belongs to the rabaptin family.
    
 
 0.551
MTRNR2L10
Humanin-like 10; Plays a role as a neuroprotective and antiapoptotic factor. Belongs to the humanin family.
      
 0.506
OR2AK2
Olfactory receptor 2AK2; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
    
 
 0.506
WDR31
WD repeat domain 31.
   
 
 0.501
EFCAB13
EF-hand calcium-binding domain-containing protein 13; EF-hand calcium binding domain 13.
   
 
 0.489
FAM25A
Protein FAM25A; Family with sequence similarity 25 member A; Belongs to the FAM25 family.
      
 0.479
EIF3CL
Eukaryotic translation initiation factor 3 subunit C-like protein; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-term [...]
      
 0.451
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
Server load: medium (46%) [HD]