close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
C19orf67UPF0575 protein C19orf67; Chromosome 19 open reading frame 67; Belongs to the UPF0575 family. (358 aa)    
Predicted Functional Partners:
C19orf53
Leydig cell tumor 10 kDa protein homolog; May have a potential role in hypercalcemia of malignancy.
      
 0.584
CCDC130
Coiled-coil domain containing 130; Belongs to the CWC16 family.
      
 0.542
C19orf57
Uncharacterized protein C19orf57; Chromosome 19 open reading frame 57.
      
 0.541
ZSWIM4
Zinc finger SWIM-type containing 4.
      
 0.477
PALM3
Paralemmin-3; ATP-binding protein, which may act as a adapter in the Toll- like receptor (TLR) signaling.
      
 0.476
PODNL1
Podocan-like protein 1; Podocan like 1.
      
 0.474
SAMD1
Atherin; May play a role in atherogenesis by immobilizing LDL in the atherial wall.
      
 0.471
ADGRE3
Adhesion G protein-coupled receptor E3; Orphan receptor that may play a role myeloid-myeloid interactions during immune and inflammatory responses. A ligand for the soluble form of this receptor is present at the surface of monocytes- derived macrophages and activated neutrophils.
      
 0.418
SLC22A18AS
Beckwith-Wiedemann syndrome chromosomal region 1 candidate gene B protein; Solute carrier family 22 member 18 antisense.
      
 0.418
DCAF15
DDB1- and CUL4-associated factor 15; May be involved in ubiquitination and degradation through a DBB1-CUL4 E3 protein-ubiquitin ligase.
      
 0.400
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.