H0YIJ7_HUMAN protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
H0YIJ7_HUMAN	MRPL17	ENSP00000449544	ENSP00000288937	Uncharacterized protein.	Mitochondrial ribosomal protein L17.	0.827
H0YIJ7_HUMAN	MRPL19	ENSP00000449544	ENSP00000377486	Uncharacterized protein.	Mitochondrial ribosomal protein L19.	0.880
H0YIJ7_HUMAN	MRPL9	ENSP00000449544	ENSP00000357823	Uncharacterized protein.	Mitochondrial ribosomal protein L9.	0.828
H0YIJ7_HUMAN	MRPS16	ENSP00000449544	ENSP00000362036	Uncharacterized protein.	Mitochondrial ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.	0.835
H0YIJ7_HUMAN	MRPS9	ENSP00000449544	ENSP00000258455	Uncharacterized protein.	Mitochondrial ribosomal protein S9.	0.843
H0YIJ7_HUMAN	MRRF	ENSP00000449544	ENSP00000343867	Uncharacterized protein.	Ribosome-recycling factor, mitochondrial; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity).	0.844
H0YIJ7_HUMAN	PDCD11	ENSP00000449544	ENSP00000358812	Uncharacterized protein.	Protein RRP5 homolog; Essential for the generation of mature 18S rRNA, specifically necessary for cleavages at sites A0, 1 and 2 of the 47S precursor. Directly interacts with U3 snoRNA.	0.880
H0YIJ7_HUMAN	RPL35	ENSP00000449544	ENSP00000259469	Uncharacterized protein.	60S ribosomal protein L35; Component of the large ribosomal subunit.	0.842
H0YIJ7_HUMAN	TSFM	ENSP00000449544	ENSP00000313877	Uncharacterized protein.	Elongation factor Ts, mitochondrial; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.	0.978
H0YIJ7_HUMAN	TUFM	ENSP00000449544	ENSP00000322439	Uncharacterized protein.	Elongation factor Tu, mitochondrial; Promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. Plays also a role in the regulation of autophagy and innate immunity. Recruits ATG5-ATG12 and NLRX1 at mitochondria and serves as a checkpoint of the RIG- I/DDX58-MAVS pathway. In turn, inhibits RLR-mediated type I interferon while promoting autophagy; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.	0.957
MRPL17	H0YIJ7_HUMAN	ENSP00000288937	ENSP00000449544	Mitochondrial ribosomal protein L17.	Uncharacterized protein.	0.827
MRPL17	MRPL19	ENSP00000288937	ENSP00000377486	Mitochondrial ribosomal protein L17.	Mitochondrial ribosomal protein L19.	0.999
MRPL17	MRPL9	ENSP00000288937	ENSP00000357823	Mitochondrial ribosomal protein L17.	Mitochondrial ribosomal protein L9.	0.998
MRPL17	MRPS16	ENSP00000288937	ENSP00000362036	Mitochondrial ribosomal protein L17.	Mitochondrial ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.	0.998
MRPL17	MRPS9	ENSP00000288937	ENSP00000258455	Mitochondrial ribosomal protein L17.	Mitochondrial ribosomal protein S9.	0.998
MRPL17	MRRF	ENSP00000288937	ENSP00000343867	Mitochondrial ribosomal protein L17.	Ribosome-recycling factor, mitochondrial; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity).	0.937
MRPL17	PDCD11	ENSP00000288937	ENSP00000358812	Mitochondrial ribosomal protein L17.	Protein RRP5 homolog; Essential for the generation of mature 18S rRNA, specifically necessary for cleavages at sites A0, 1 and 2 of the 47S precursor. Directly interacts with U3 snoRNA.	0.964
MRPL17	RPL35	ENSP00000288937	ENSP00000259469	Mitochondrial ribosomal protein L17.	60S ribosomal protein L35; Component of the large ribosomal subunit.	0.984
MRPL17	TSFM	ENSP00000288937	ENSP00000313877	Mitochondrial ribosomal protein L17.	Elongation factor Ts, mitochondrial; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.	0.938
MRPL17	TUFM	ENSP00000288937	ENSP00000322439	Mitochondrial ribosomal protein L17.	Elongation factor Tu, mitochondrial; Promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. Plays also a role in the regulation of autophagy and innate immunity. Recruits ATG5-ATG12 and NLRX1 at mitochondria and serves as a checkpoint of the RIG- I/DDX58-MAVS pathway. In turn, inhibits RLR-mediated type I interferon while promoting autophagy; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.	0.997