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DUX4L7 protein (human) - STRING interaction network
"DUX4L7" - Double homeobox 4 like 7 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DUX4L7Double homeobox 4 like 7; PRD class homeoboxes and pseudogenes (424 aa)    
Predicted Functional Partners:
FRG2
Protein FRG2; FSHD region gene 2 (279 aa)
           
  0.848
SMCHD1
Structural maintenance of chromosomes flexible hinge domain-containing protein 1; Required for maintenance of X inactivation in females and hypermethylation of CpG islands associated with inactive X. Involved in a pathway that mediates the methylation of a subset of CpG islands slowly and requires the methyltransferase DNMT3B (By similarity). Required for DUX4 silencing in somatic cells (2005 aa)
           
  0.840
DUX4L2
Double homeobox 4 like 2; May be involved in transcriptional regulation; PRD class homeoboxes and pseudogenes (424 aa)
     
 
0.820
DUX4L8
Double homeodomain protein DUX4-s; PRD class homeoboxes and pseudogenes (424 aa)
     
   
0.814
DUX4L3
Double homeobox protein 4-like protein 2; May be involved in transcriptional regulation; PRD class homeoboxes and pseudogenes (424 aa)
     
   
0.810
DUX4L6
Double homeobox 4 like 6; PRD class homeoboxes and pseudogenes (424 aa)
     
   
0.809
DUX4L1
Double homeobox 4 like 1; PRD class homeoboxes and pseudogenes (424 aa)
     
 
0.808
ETV5
ETS translocation variant 5; Binds to DNA sequences containing the consensus nucleotide core sequence 5’-GGAA.-3’; Belongs to the ETS family (510 aa)
       
 
  0.806
DUX4L5
Double homeobox 4 like 5; PRD class homeoboxes and pseudogenes (424 aa)
     
   
0.806
DUX4
Double homeobox protein 4; Involved in transcriptional regulation. May regulate microRNA (miRNA) expression; Belongs to the paired homeobox family (424 aa)
       
 
0.801
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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