STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DUXADouble homeobox protein A; Putative transcription factor; Belongs to the paired homeobox family. (204 aa)    
Predicted Functional Partners:
LEUTX
Leucine twenty homeobox.
   
 
 0.746
TPRX1
Tetrapeptide repeat homeobox 1.
   
  
 0.730
ARGFX
Arginine-fifty homeobox; Putative transcription factor.
   
 
 0.724
NANOGNB
NANOG neighbor homeobox.
   
  
 0.628
ZSCAN4
Zinc finger and SCAN domain-containing protein 4; Embryonic stem (ES) cell-specific transcription factor required to regulate ES cell pluripotency. Binds telomeres and plays a key role in genomic stability in ES cells by regulating telomere elongation. Acts as an activator of spontaneous telomere sister chromatid exchange (T-SCE) and telomere elongation in undifferentiated ES cells (By similarity).
   
 
 0.612
MBD3L3
methyl-CpG binding domain protein 3 like 3.
   
 
 0.533
ADAT1
tRNA-specific adenosine deaminase 1; Specifically deaminates adenosine-37 to inosine in tRNA-Ala.
      
 0.481
PRAMEF5
PRAME family member 5; Belongs to the PRAME family.
   
  
 0.455
RHOXF2B
Rhox homeobox family member 2B; Transcription factor maybe involved in reproductive processes. Modulates expression of target genes encoding proteins involved in processes relevant to spermatogenesis. Belongs to the paired-like homeobox family. PEPP subfamily.
      
 0.448
PLAC9
Placenta-specific protein 9; Placenta associated 9; Belongs to the PLAC9 family.
      
 0.448
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.