C5orf63 protein (human) - STRING interaction network

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C5orf63

Glutaredoxin-like protein C5orf63; Chromosome 5 open reading frame 63. (138 aa)

Predicted Functional Partners:

MARCHF3

0.570

MINAR2

0.542

VOPP1

0.478

C15orf40

0.470

DENND5B

0.454

TEX43

0.452

C8orf82

0.450

OR5H14

0.448

OXLD1

0.435

PDIA6

0.409

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C15orf40	C5orf63	ENSP00000403987	ENSP00000454153	UPF0235 protein C15orf40; Chromosome 15 open reading frame 40.	Glutaredoxin-like protein C5orf63; Chromosome 5 open reading frame 63.	0.470
C15orf40	C8orf82	ENSP00000403987	ENSP00000436621	UPF0235 protein C15orf40; Chromosome 15 open reading frame 40.	UPF0598 protein C8orf82; Chromosome 8 open reading frame 82.	0.579
C5orf63	C15orf40	ENSP00000454153	ENSP00000403987	Glutaredoxin-like protein C5orf63; Chromosome 5 open reading frame 63.	UPF0235 protein C15orf40; Chromosome 15 open reading frame 40.	0.470
C5orf63	C8orf82	ENSP00000454153	ENSP00000436621	Glutaredoxin-like protein C5orf63; Chromosome 5 open reading frame 63.	UPF0598 protein C8orf82; Chromosome 8 open reading frame 82.	0.450
C5orf63	DENND5B	ENSP00000454153	ENSP00000444889	Glutaredoxin-like protein C5orf63; Chromosome 5 open reading frame 63.	DENN domain-containing protein 5B; Guanine nucleotide exchange factor (GEF) which may activate RAB39A and/or RAB39B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form.	0.454
C5orf63	MARCHF3	ENSP00000454153	ENSP00000309141	Glutaredoxin-like protein C5orf63; Chromosome 5 open reading frame 63.	E3 ubiquitin-protein ligase MARCHF3; E3 ubiquitin-protein ligase which may be involved in endosomal trafficking. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.	0.570
C5orf63	MINAR2	ENSP00000454153	ENSP00000454268	Glutaredoxin-like protein C5orf63; Chromosome 5 open reading frame 63.	Major intrinsically disordered NOTCH2-binding receptor 1-like; Membrane integral NOTCH2 associated receptor 2.	0.542
C5orf63	OR5H14	ENSP00000454153	ENSP00000493226	Glutaredoxin-like protein C5orf63; Chromosome 5 open reading frame 63.	Olfactory receptor 5H14; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.	0.448
C5orf63	OXLD1	ENSP00000454153	ENSP00000363873	Glutaredoxin-like protein C5orf63; Chromosome 5 open reading frame 63.	Oxidoreductase-like domain-containing protein 1; Oxidoreductase like domain containing 1.	0.435
C5orf63	PDIA6	ENSP00000454153	ENSP00000385385	Glutaredoxin-like protein C5orf63; Chromosome 5 open reading frame 63.	Protein disulfide-isomerase A6; May function as a chaperone that inhibits aggregation of misfolded proteins. Negatively regulates the unfolded protein response (UPR) through binding to UPR sensors such as ERN1, which in turn inactivates ERN1 signaling. May also regulate the UPR via the EIF2AK3 UPR sensor. Plays a role in platelet aggregation and activation by agonists such as convulxin, collagen and thrombin.	0.409
C5orf63	TEX43	ENSP00000454153	ENSP00000349669	Glutaredoxin-like protein C5orf63; Chromosome 5 open reading frame 63.	Testis-expressed protein 43; Testis expressed 43.	0.452
C5orf63	VOPP1	ENSP00000454153	ENSP00000285279	Glutaredoxin-like protein C5orf63; Chromosome 5 open reading frame 63.	Vesicular, overexpressed in cancer, prosurvival protein 1; Increases the transcriptional activity of NFKB1 by facilitating its nuclear translocation, DNA-binding and associated apoptotic response, when overexpressed; Belongs to the VOPP1/ECOP family.	0.478
C8orf82	C15orf40	ENSP00000436621	ENSP00000403987	UPF0598 protein C8orf82; Chromosome 8 open reading frame 82.	UPF0235 protein C15orf40; Chromosome 15 open reading frame 40.	0.579
C8orf82	C5orf63	ENSP00000436621	ENSP00000454153	UPF0598 protein C8orf82; Chromosome 8 open reading frame 82.	Glutaredoxin-like protein C5orf63; Chromosome 5 open reading frame 63.	0.450
DENND5B	C5orf63	ENSP00000444889	ENSP00000454153	DENN domain-containing protein 5B; Guanine nucleotide exchange factor (GEF) which may activate RAB39A and/or RAB39B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form.	Glutaredoxin-like protein C5orf63; Chromosome 5 open reading frame 63.	0.454
DENND5B	VOPP1	ENSP00000444889	ENSP00000285279	DENN domain-containing protein 5B; Guanine nucleotide exchange factor (GEF) which may activate RAB39A and/or RAB39B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form.	Vesicular, overexpressed in cancer, prosurvival protein 1; Increases the transcriptional activity of NFKB1 by facilitating its nuclear translocation, DNA-binding and associated apoptotic response, when overexpressed; Belongs to the VOPP1/ECOP family.	0.468
MARCHF3	C5orf63	ENSP00000309141	ENSP00000454153	E3 ubiquitin-protein ligase MARCHF3; E3 ubiquitin-protein ligase which may be involved in endosomal trafficking. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.	Glutaredoxin-like protein C5orf63; Chromosome 5 open reading frame 63.	0.570
MARCHF3	MINAR2	ENSP00000309141	ENSP00000454268	E3 ubiquitin-protein ligase MARCHF3; E3 ubiquitin-protein ligase which may be involved in endosomal trafficking. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.	Major intrinsically disordered NOTCH2-binding receptor 1-like; Membrane integral NOTCH2 associated receptor 2.	0.432
MARCHF3	TEX43	ENSP00000309141	ENSP00000349669	E3 ubiquitin-protein ligase MARCHF3; E3 ubiquitin-protein ligase which may be involved in endosomal trafficking. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.	Testis-expressed protein 43; Testis expressed 43.	0.573
MINAR2	C5orf63	ENSP00000454268	ENSP00000454153	Major intrinsically disordered NOTCH2-binding receptor 1-like; Membrane integral NOTCH2 associated receptor 2.	Glutaredoxin-like protein C5orf63; Chromosome 5 open reading frame 63.	0.542