TMC7 protein (human) - STRING interaction network

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Known Interactions

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Predicted Interactions

gene neighborhood

gene fusions

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textmining

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protein homology

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Score

TMC7

Transmembrane channel-like protein 7; Probable ion channel. (758 aa)

Predicted Functional Partners:

LRRIQ3

0.742

FRMD3

0.612

SAMD5

0.588

HLCS

0.518

CIB1

0.406

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CIB1	TMC7	ENSP00000479860	ENSP00000455041	Calcium and integrin-binding protein 1; Calcium-binding protein that plays a role in the regulation of numerous cellular processes, such as cell differentiation, cell division, cell proliferation, cell migration, thrombosis, angiogenesis, cardiac hypertrophy and apoptosis. Involved in bone marrow megakaryocyte differentiation by negatively regulating thrombopoietin- mediated signaling pathway. Participates in the endomitotic cell cycle of megakaryocyte, a form of mitosis in which both karyokinesis and cytokinesis are interrupted. Plays a role in integrin signaling by negatively regulat [...]	Transmembrane channel-like protein 7; Probable ion channel.	0.406
FRMD3	LRRIQ3	ENSP00000303508	ENSP00000346414	FERM domain-containing protein 3; Putative tumor suppressor gene that may be implicated in the origin and progression of lung cancer.	Leucine rich repeats and IQ motif containing 3.	0.645
FRMD3	SAMD5	ENSP00000303508	ENSP00000356444	FERM domain-containing protein 3; Putative tumor suppressor gene that may be implicated in the origin and progression of lung cancer.	Sterile alpha motif domain containing 5.	0.616
FRMD3	TMC7	ENSP00000303508	ENSP00000455041	FERM domain-containing protein 3; Putative tumor suppressor gene that may be implicated in the origin and progression of lung cancer.	Transmembrane channel-like protein 7; Probable ion channel.	0.612
HLCS	TMC7	ENSP00000382071	ENSP00000455041	Biotin--[propionyl-CoA-carboxylase [ATP-hydrolyzing]] ligase; Biotin--protein ligase catalyzing the biotinylation of the 4 biotin-dependent carboxylases acetyl-CoA-carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, and methylcrotonyl-CoA carboxylase.	Transmembrane channel-like protein 7; Probable ion channel.	0.518
LRRIQ3	FRMD3	ENSP00000346414	ENSP00000303508	Leucine rich repeats and IQ motif containing 3.	FERM domain-containing protein 3; Putative tumor suppressor gene that may be implicated in the origin and progression of lung cancer.	0.645
LRRIQ3	SAMD5	ENSP00000346414	ENSP00000356444	Leucine rich repeats and IQ motif containing 3.	Sterile alpha motif domain containing 5.	0.670
LRRIQ3	TMC7	ENSP00000346414	ENSP00000455041	Leucine rich repeats and IQ motif containing 3.	Transmembrane channel-like protein 7; Probable ion channel.	0.742
SAMD5	FRMD3	ENSP00000356444	ENSP00000303508	Sterile alpha motif domain containing 5.	FERM domain-containing protein 3; Putative tumor suppressor gene that may be implicated in the origin and progression of lung cancer.	0.616
SAMD5	LRRIQ3	ENSP00000356444	ENSP00000346414	Sterile alpha motif domain containing 5.	Leucine rich repeats and IQ motif containing 3.	0.670
SAMD5	TMC7	ENSP00000356444	ENSP00000455041	Sterile alpha motif domain containing 5.	Transmembrane channel-like protein 7; Probable ion channel.	0.588
TMC7	CIB1	ENSP00000455041	ENSP00000479860	Transmembrane channel-like protein 7; Probable ion channel.	Calcium and integrin-binding protein 1; Calcium-binding protein that plays a role in the regulation of numerous cellular processes, such as cell differentiation, cell division, cell proliferation, cell migration, thrombosis, angiogenesis, cardiac hypertrophy and apoptosis. Involved in bone marrow megakaryocyte differentiation by negatively regulating thrombopoietin- mediated signaling pathway. Participates in the endomitotic cell cycle of megakaryocyte, a form of mitosis in which both karyokinesis and cytokinesis are interrupted. Plays a role in integrin signaling by negatively regulat [...]	0.406
TMC7	FRMD3	ENSP00000455041	ENSP00000303508	Transmembrane channel-like protein 7; Probable ion channel.	FERM domain-containing protein 3; Putative tumor suppressor gene that may be implicated in the origin and progression of lung cancer.	0.612
TMC7	HLCS	ENSP00000455041	ENSP00000382071	Transmembrane channel-like protein 7; Probable ion channel.	Biotin--[propionyl-CoA-carboxylase [ATP-hydrolyzing]] ligase; Biotin--protein ligase catalyzing the biotinylation of the 4 biotin-dependent carboxylases acetyl-CoA-carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, and methylcrotonyl-CoA carboxylase.	0.518
TMC7	LRRIQ3	ENSP00000455041	ENSP00000346414	Transmembrane channel-like protein 7; Probable ion channel.	Leucine rich repeats and IQ motif containing 3.	0.742
TMC7	SAMD5	ENSP00000455041	ENSP00000356444	Transmembrane channel-like protein 7; Probable ion channel.	Sterile alpha motif domain containing 5.	0.588