node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AMER3 | FAM131B | ENSP00000392700 | ENSP00000410603 | APC membrane recruitment protein 3; Regulator of the canonical Wnt signaling pathway. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane (By similarity) | Protein FAM131B; Family with sequence similarity 131 member B; Belongs to the FAM131 family | 0.549 |
AMER3 | FAM171B | ENSP00000392700 | ENSP00000304108 | APC membrane recruitment protein 3; Regulator of the canonical Wnt signaling pathway. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane (By similarity) | Protein FAM171B; Family with sequence similarity 171 member B; Belongs to the FAM171 family | 0.594 |
AMER3 | FAM189A1 | ENSP00000392700 | ENSP00000261275 | APC membrane recruitment protein 3; Regulator of the canonical Wnt signaling pathway. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane (By similarity) | Protein FAM189A1; Family with sequence similarity 189 member A1; Belongs to the FAM189 family | 0.600 |
AMER3 | FAM19A1 | ENSP00000392700 | ENSP00000418575 | APC membrane recruitment protein 3; Regulator of the canonical Wnt signaling pathway. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane (By similarity) | Protein FAM19A1; Family with sequence similarity 19 member A1, C-C motif chemokine like | 0.576 |
AMER3 | TMEM145 | ENSP00000392700 | ENSP00000301204 | APC membrane recruitment protein 3; Regulator of the canonical Wnt signaling pathway. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane (By similarity) | Transmembrane protein 145 | 0.604 |
AMER3 | TMEM178A | ENSP00000392700 | ENSP00000281961 | APC membrane recruitment protein 3; Regulator of the canonical Wnt signaling pathway. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane (By similarity) | Transmembrane protein 178A; Acts as a negative regulator of osteoclast differentiation in basal and inflammatory conditions by regulating TNFSF11-induced Ca (2+) fluxes, thereby controlling the induction of NFATC1; Belongs to the TMEM178 family | 0.574 |
AMER3 | TMEM179 | ENSP00000392700 | ENSP00000450958 | APC membrane recruitment protein 3; Regulator of the canonical Wnt signaling pathway. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane (By similarity) | Transmembrane protein 179; Belongs to the TMEM179 family | 0.623 |
AMER3 | TMEM59L | ENSP00000392700 | ENSP00000470879 | APC membrane recruitment protein 3; Regulator of the canonical Wnt signaling pathway. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane (By similarity) | Transmembrane protein 59-like; Modulates the O-glycosylation and complex N- glycosylation steps occurring during the Golgi maturation of APP. Inhibits APP transport to the cell surface and further shedding | 0.535 |
AMER3 | TMEM88B | ENSP00000392700 | ENSP00000455099 | APC membrane recruitment protein 3; Regulator of the canonical Wnt signaling pathway. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane (By similarity) | Transmembrane protein 88B | 0.610 |
FAM131B | AMER3 | ENSP00000410603 | ENSP00000392700 | Protein FAM131B; Family with sequence similarity 131 member B; Belongs to the FAM131 family | APC membrane recruitment protein 3; Regulator of the canonical Wnt signaling pathway. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane (By similarity) | 0.549 |
FAM131B | FAM171B | ENSP00000410603 | ENSP00000304108 | Protein FAM131B; Family with sequence similarity 131 member B; Belongs to the FAM131 family | Protein FAM171B; Family with sequence similarity 171 member B; Belongs to the FAM171 family | 0.548 |
FAM131B | FAM189A1 | ENSP00000410603 | ENSP00000261275 | Protein FAM131B; Family with sequence similarity 131 member B; Belongs to the FAM131 family | Protein FAM189A1; Family with sequence similarity 189 member A1; Belongs to the FAM189 family | 0.601 |
FAM131B | FAM19A1 | ENSP00000410603 | ENSP00000418575 | Protein FAM131B; Family with sequence similarity 131 member B; Belongs to the FAM131 family | Protein FAM19A1; Family with sequence similarity 19 member A1, C-C motif chemokine like | 0.540 |
FAM131B | TMEM145 | ENSP00000410603 | ENSP00000301204 | Protein FAM131B; Family with sequence similarity 131 member B; Belongs to the FAM131 family | Transmembrane protein 145 | 0.517 |
FAM131B | TMEM178A | ENSP00000410603 | ENSP00000281961 | Protein FAM131B; Family with sequence similarity 131 member B; Belongs to the FAM131 family | Transmembrane protein 178A; Acts as a negative regulator of osteoclast differentiation in basal and inflammatory conditions by regulating TNFSF11-induced Ca (2+) fluxes, thereby controlling the induction of NFATC1; Belongs to the TMEM178 family | 0.581 |
FAM131B | TMEM179 | ENSP00000410603 | ENSP00000450958 | Protein FAM131B; Family with sequence similarity 131 member B; Belongs to the FAM131 family | Transmembrane protein 179; Belongs to the TMEM179 family | 0.649 |
FAM131B | TMEM59L | ENSP00000410603 | ENSP00000470879 | Protein FAM131B; Family with sequence similarity 131 member B; Belongs to the FAM131 family | Transmembrane protein 59-like; Modulates the O-glycosylation and complex N- glycosylation steps occurring during the Golgi maturation of APP. Inhibits APP transport to the cell surface and further shedding | 0.613 |
FAM131B | TMEM88B | ENSP00000410603 | ENSP00000455099 | Protein FAM131B; Family with sequence similarity 131 member B; Belongs to the FAM131 family | Transmembrane protein 88B | 0.623 |
FAM171B | AMER3 | ENSP00000304108 | ENSP00000392700 | Protein FAM171B; Family with sequence similarity 171 member B; Belongs to the FAM171 family | APC membrane recruitment protein 3; Regulator of the canonical Wnt signaling pathway. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane (By similarity) | 0.594 |
FAM171B | FAM131B | ENSP00000304108 | ENSP00000410603 | Protein FAM171B; Family with sequence similarity 171 member B; Belongs to the FAM171 family | Protein FAM131B; Family with sequence similarity 131 member B; Belongs to the FAM131 family | 0.548 |