STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMEM88BTransmembrane protein 88B (163 aa)    
Predicted Functional Partners:
TMEM179
Transmembrane protein 179; Belongs to the TMEM179 family
   
  
 0.662
TMEM178A
Transmembrane protein 178A; Acts as a negative regulator of osteoclast differentiation in basal and inflammatory conditions by regulating TNFSF11-induced Ca (2+) fluxes, thereby controlling the induction of NFATC1; Belongs to the TMEM178 family
   
  
 0.632
FAM131B
Protein FAM131B; Family with sequence similarity 131 member B; Belongs to the FAM131 family
   
  
 0.623
FAM189A1
Protein FAM189A1; Family with sequence similarity 189 member A1; Belongs to the FAM189 family
   
  
 0.621
TMEM145
Transmembrane protein 145
   
  
 0.620
FAM19A1
Protein FAM19A1; Family with sequence similarity 19 member A1, C-C motif chemokine like
   
  
 0.617
TMEM240
Transmembrane protein 240; Belongs to the TMEM240 family
   
  
 0.615
AMER3
APC membrane recruitment protein 3; Regulator of the canonical Wnt signaling pathway. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane (By similarity)
   
  
 0.610
TMEM59L
Transmembrane protein 59-like; Modulates the O-glycosylation and complex N- glycosylation steps occurring during the Golgi maturation of APP. Inhibits APP transport to the cell surface and further shedding
   
  
 0.609
FAM171B
Protein FAM171B; Family with sequence similarity 171 member B; Belongs to the FAM171 family
   
  
 0.606
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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