| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ATXN1 | ATXN1L | ENSP00000244769 | ENSP00000415822 | Ataxin-1; Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ- mediated repression. Binds RNA in vitro. May be involved in RNA metabolism. In concert with CIC and ATXN1L, involved in brain development (By similarity). | Ataxin-1-like; Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ- mediated repression. Can suppress ATXN1 cytotoxicity in spinocerebellar ataxia type 1 (SCA1). In concert with CIC and ATXN1, involved in brain development (By similarity). | 0.970 |
| ATXN1 | KIF13A | ENSP00000244769 | ENSP00000259711 | Ataxin-1; Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ- mediated repression. Binds RNA in vitro. May be involved in RNA metabolism. In concert with CIC and ATXN1L, involved in brain development (By similarity). | Kinesin-like protein KIF13A; Plus end-directed microtubule-dependent motor protein involved in intracellular transport and regulating various processes such as mannose-6-phosphate receptor (M6PR) transport to the plasma membrane, endosomal sorting during melanosome biogenesis and cytokinesis. Mediates the transport of M6PR-containing vesicles from trans-Golgi network to the plasma membrane via direct interaction with the AP-1 complex. During melanosome maturation, required for delivering melanogenic enzymes from recycling endosomes to nascent melanosomes by creating peripheral recyclin [...] | 0.403 |
| ATXN1 | STMND1 | ENSP00000244769 | ENSP00000455698 | Ataxin-1; Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ- mediated repression. Binds RNA in vitro. May be involved in RNA metabolism. In concert with CIC and ATXN1L, involved in brain development (By similarity). | Stathmin domain containing 1. | 0.594 |
| ATXN1L | ATXN1 | ENSP00000415822 | ENSP00000244769 | Ataxin-1-like; Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ- mediated repression. Can suppress ATXN1 cytotoxicity in spinocerebellar ataxia type 1 (SCA1). In concert with CIC and ATXN1, involved in brain development (By similarity). | Ataxin-1; Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ- mediated repression. Binds RNA in vitro. May be involved in RNA metabolism. In concert with CIC and ATXN1L, involved in brain development (By similarity). | 0.970 |
| ATXN1L | STMND1 | ENSP00000415822 | ENSP00000455698 | Ataxin-1-like; Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ- mediated repression. Can suppress ATXN1 cytotoxicity in spinocerebellar ataxia type 1 (SCA1). In concert with CIC and ATXN1, involved in brain development (By similarity). | Stathmin domain containing 1. | 0.458 |
| C1orf158 | CDC20B | ENSP00000477802 | ENSP00000370781 | Uncharacterized protein C1orf158; Chromosome 1 open reading frame 158. | Cell division cycle 20B; Belongs to the WD repeat CDC20/Fizzy family. | 0.935 |
| C1orf158 | STMND1 | ENSP00000477802 | ENSP00000455698 | Uncharacterized protein C1orf158; Chromosome 1 open reading frame 158. | Stathmin domain containing 1. | 0.533 |
| CDC20B | C1orf158 | ENSP00000370781 | ENSP00000477802 | Cell division cycle 20B; Belongs to the WD repeat CDC20/Fizzy family. | Uncharacterized protein C1orf158; Chromosome 1 open reading frame 158. | 0.935 |
| CDC20B | STMND1 | ENSP00000370781 | ENSP00000455698 | Cell division cycle 20B; Belongs to the WD repeat CDC20/Fizzy family. | Stathmin domain containing 1. | 0.618 |
| FAM8A1 | STMND1 | ENSP00000259963 | ENSP00000455698 | Protein FAM8A1; Family with sequence similarity 8 member A1. | Stathmin domain containing 1. | 0.474 |
| KIF13A | ATXN1 | ENSP00000259711 | ENSP00000244769 | Kinesin-like protein KIF13A; Plus end-directed microtubule-dependent motor protein involved in intracellular transport and regulating various processes such as mannose-6-phosphate receptor (M6PR) transport to the plasma membrane, endosomal sorting during melanosome biogenesis and cytokinesis. Mediates the transport of M6PR-containing vesicles from trans-Golgi network to the plasma membrane via direct interaction with the AP-1 complex. During melanosome maturation, required for delivering melanogenic enzymes from recycling endosomes to nascent melanosomes by creating peripheral recyclin [...] | Ataxin-1; Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ- mediated repression. Binds RNA in vitro. May be involved in RNA metabolism. In concert with CIC and ATXN1L, involved in brain development (By similarity). | 0.403 |
| KIF13A | STMND1 | ENSP00000259711 | ENSP00000455698 | Kinesin-like protein KIF13A; Plus end-directed microtubule-dependent motor protein involved in intracellular transport and regulating various processes such as mannose-6-phosphate receptor (M6PR) transport to the plasma membrane, endosomal sorting during melanosome biogenesis and cytokinesis. Mediates the transport of M6PR-containing vesicles from trans-Golgi network to the plasma membrane via direct interaction with the AP-1 complex. During melanosome maturation, required for delivering melanogenic enzymes from recycling endosomes to nascent melanosomes by creating peripheral recyclin [...] | Stathmin domain containing 1. | 0.645 |
| MYLIP | STMND1 | ENSP00000349298 | ENSP00000455698 | E3 ubiquitin-protein ligase MYLIP; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of myosin regulatory light chain (MRLC), LDLR, VLDLR and LRP8. Activity depends on E2 enzymes of the UBE2D family. Proteasomal degradation of MRLC leads to inhibit neurite outgrowth in presence of NGF by counteracting the stabilization of MRLC by saposin-like protein (CNPY2/MSAP) and reducing CNPY2-stimulated neurite outgrowth. Acts as a sterol-dependent inhibitor of cellular cholesterol uptake by mediating ubiquitination and subsequent degradation of LDLR. | Stathmin domain containing 1. | 0.472 |
| RBM24 | STMND1 | ENSP00000368341 | ENSP00000455698 | RNA-binding protein 24; Multifunctional RNA-binding protein involved in the regulation of pre-mRNA splicing, mRNA stability and mRNA translation important for cell fate decision and differentiation. Plays a major role in pre-mRNA alternative splicing regulation. Mediates preferentially muscle-specific exon inclusion in numerous mRNAs important for striated cardiac and skeletal muscle cell differentiation. Binds to intronic splicing enhancer (ISE) composed of stretches of GU-rich motifs localized in flanking intron of exon that will be included by alternative splicing (By similarity). I [...] | Stathmin domain containing 1. | 0.570 |
| SMOC2 | STMND1 | ENSP00000346537 | ENSP00000455698 | SPARC-related modular calcium-binding protein 2; Promotes matrix assembly and cell adhesiveness (By similarity). Can stimulate endothelial cell proliferation, migration, as well as angiogenesis. | Stathmin domain containing 1. | 0.512 |
| STMND1 | ATXN1 | ENSP00000455698 | ENSP00000244769 | Stathmin domain containing 1. | Ataxin-1; Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ- mediated repression. Binds RNA in vitro. May be involved in RNA metabolism. In concert with CIC and ATXN1L, involved in brain development (By similarity). | 0.594 |
| STMND1 | ATXN1L | ENSP00000455698 | ENSP00000415822 | Stathmin domain containing 1. | Ataxin-1-like; Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ- mediated repression. Can suppress ATXN1 cytotoxicity in spinocerebellar ataxia type 1 (SCA1). In concert with CIC and ATXN1, involved in brain development (By similarity). | 0.458 |
| STMND1 | C1orf158 | ENSP00000455698 | ENSP00000477802 | Stathmin domain containing 1. | Uncharacterized protein C1orf158; Chromosome 1 open reading frame 158. | 0.533 |
| STMND1 | CDC20B | ENSP00000455698 | ENSP00000370781 | Stathmin domain containing 1. | Cell division cycle 20B; Belongs to the WD repeat CDC20/Fizzy family. | 0.618 |
| STMND1 | FAM8A1 | ENSP00000455698 | ENSP00000259963 | Stathmin domain containing 1. | Protein FAM8A1; Family with sequence similarity 8 member A1. | 0.474 |
STRING v12.5 is now available!
