Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
TEX38Testis-expressed protein 38; Testis expressed 38. (206 aa)    
Predicted Functional Partners:
PRR30
Proline-rich protein 30; Proline rich 30.
   
  
 0.584
C20orf27
UPF0687 protein C20orf27; Chromosome 20 open reading frame 27.
      
 0.577
FAM205A
Protein FAM205A; Family with sequence similarity 205 member A.
   
  
 0.556
FAM166A
Protein FAM166A; Family with sequence similarity 166 member A.
   
  
 0.547
EFCAB14
EF-hand calcium-binding domain-containing protein 14; EF-hand calcium binding domain 14.
      
 0.540
LYZL6
Lysozyme-like protein 6; May be involved sperm-egg plasma membrane adhesion and fusion during fertilization. Exhibits bacteriolytic activity in vitro against Micrococcus luteus and Staphylococcus aureus. Shows weak bacteriolytic activity against Gram-positive bacteria at physiological pH. Bacteriolytic activity is pH-dependent, with a maximum at around pH 5.6.
   
  
 0.512
C1orf194
Protein C1orf194; May play an important role for the maintenance of myelin-axon integrity (By similarity). May affect intracellular Ca(2+) homeostasis.
   
  
 0.503
ODF4
Outer dense fiber protein 4; Component of the outer dense fibers (ODF) of spermatozoa which could be involved in sperm tail structure, sperm movement and general organization of cellular cytoskeleton.
      
 0.493
CNBD2
Cyclic nucleotide-binding domain-containing protein 2; Essential for male fertility. Plays an important role in spermatogenesis and regulates sperm motility by controlling the development of the flagellar bending of sperm.
   
  
 0.475
MEIG1
Meiosis expressed gene 1 protein homolog; Essential for spermiogenesis.
   
  
 0.473
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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