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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SMLR1Small leucine rich protein 1. (107 aa)    
Predicted Functional Partners:
CXorf58
Putative uncharacterized protein CXorf58; Chromosome X open reading frame 58.
      
 0.770
EFCAB3
EF-hand calcium-binding domain-containing protein 3; EF-hand calcium binding domain 3.
      
 0.598
CENPBD1
CENPB DNA-binding domain containing 1.
      
 0.584
C7orf25
UPF0415 protein C7orf25; Chromosome 7 open reading frame 25; Belongs to the UPF0415 family.
      
 0.580
TMEM244
Transmembrane protein 244.
      
 0.574
BSCL2
Seipin; Is a regulator of lipid catabolism essential for adipocyte differentiation. May also be involved in the central regulation of energy homeostasis (By similarity). Necessary for correct lipid storage and lipid droplets maintenance; may play a tissue-autonomous role in controlling lipid storage in adipocytes and in preventing ectopic lipid droplet formation in non-adipose tissues.
    
 
 0.562
RSRP1
Arginine and serine rich protein 1.
      
 0.507
HUS1B
Checkpoint protein HUS1B; HUS1 checkpoint clamp component B; Belongs to the HUS1 family.
      
 0.506
SMIM3
Small integral membrane protein 3.
      
 0.477
TSEN54
tRNA-splicing endonuclease subunit Sen54; Non-catalytic subunit of the tRNA-splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural features of the tRNA bo [...]
      
 0.421
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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