RNF151 protein (human) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

RNF151

RING finger protein 151; May be involved in acrosome formation of spermatids. (245 aa)

Predicted Functional Partners:

RNF133

0.556

FAM133A

0.544

RNF126

0.529

BRICD5

0.519

RNF175

0.489

UBE2D2

0.479

ENSP00000494172

0.479

SH2D7

0.474

METTL24

0.473

ABT1

0.456

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABT1	RNF151	ENSP00000274849	ENSP00000456566	Activator of basal transcription 1; Could be a novel TATA-binding protein (TBP) which can function as a basal transcription activator. Can act as a regulator of basal transcription for class II genes (By similarity); Belongs to the ESF2/ABP1 family.	RING finger protein 151; May be involved in acrosome formation of spermatids.	0.456
BRICD5	RNF151	ENSP00000332389	ENSP00000456566	BRICHOS domain containing 5.	RING finger protein 151; May be involved in acrosome formation of spermatids.	0.519
ENSP00000494172	RNF151	ENSP00000494172	ENSP00000456566	RING-type domain-containing protein.	RING finger protein 151; May be involved in acrosome formation of spermatids.	0.479
FAM133A	RNF151	ENSP00000318974	ENSP00000456566	Protein FAM133A; Family with sequence similarity 133 member A.	RING finger protein 151; May be involved in acrosome formation of spermatids.	0.544
METTL24	RNF151	ENSP00000344071	ENSP00000456566	Methyltransferase-like protein 24; Methyltransferase like 24.	RING finger protein 151; May be involved in acrosome formation of spermatids.	0.473
RNF126	RNF151	ENSP00000292363	ENSP00000456566	E3 ubiquitin-protein ligase RNF126; E3 ubiquitin-protein ligase that mediates ubiquitination oF target proteins. Depending on the associated E2 ligase, mediates 'Lys-48'- and 'Lys-63'- linked polyubiquitination of substrates (By similarity). Part of a BAG6-dependent quality control process ensuring that proteins of the secretory pathway that are mislocalized to the cytosol are degraded by the proteasome. Probably acts by providing the ubiquitin ligase activity associated with the BAG6 complex and be responsible for ubiquitination of the hydrophobic mislocalized proteins and their targe [...]	RING finger protein 151; May be involved in acrosome formation of spermatids.	0.529
RNF126	UBE2D2	ENSP00000292363	ENSP00000381717	E3 ubiquitin-protein ligase RNF126; E3 ubiquitin-protein ligase that mediates ubiquitination oF target proteins. Depending on the associated E2 ligase, mediates 'Lys-48'- and 'Lys-63'- linked polyubiquitination of substrates (By similarity). Part of a BAG6-dependent quality control process ensuring that proteins of the secretory pathway that are mislocalized to the cytosol are degraded by the proteasome. Probably acts by providing the ubiquitin ligase activity associated with the BAG6 complex and be responsible for ubiquitination of the hydrophobic mislocalized proteins and their targe [...]	Ubiquitin-conjugating enzyme E2 D2; Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'- linked polyubiquitination. Mediates the selective degradation of short- lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and autoubiquitination of STUB1 and TRAF6. Involved in the signal-induced conjugation and subsequent degradation of NFKBIA, FBXW2-mediated GCM1 ubiquitination and degradation, MDM2-dependent degradation of p53/TP53 and the activation of [...]	0.888
RNF133	RNF151	ENSP00000344489	ENSP00000456566	E3 ubiquitin-protein ligase RNF133; Has E3 ubiquitin-protein ligase activity.	RING finger protein 151; May be involved in acrosome formation of spermatids.	0.556
RNF151	ABT1	ENSP00000456566	ENSP00000274849	RING finger protein 151; May be involved in acrosome formation of spermatids.	Activator of basal transcription 1; Could be a novel TATA-binding protein (TBP) which can function as a basal transcription activator. Can act as a regulator of basal transcription for class II genes (By similarity); Belongs to the ESF2/ABP1 family.	0.456
RNF151	BRICD5	ENSP00000456566	ENSP00000332389	RING finger protein 151; May be involved in acrosome formation of spermatids.	BRICHOS domain containing 5.	0.519
RNF151	ENSP00000494172	ENSP00000456566	ENSP00000494172	RING finger protein 151; May be involved in acrosome formation of spermatids.	RING-type domain-containing protein.	0.479
RNF151	FAM133A	ENSP00000456566	ENSP00000318974	RING finger protein 151; May be involved in acrosome formation of spermatids.	Protein FAM133A; Family with sequence similarity 133 member A.	0.544
RNF151	METTL24	ENSP00000456566	ENSP00000344071	RING finger protein 151; May be involved in acrosome formation of spermatids.	Methyltransferase-like protein 24; Methyltransferase like 24.	0.473
RNF151	RNF126	ENSP00000456566	ENSP00000292363	RING finger protein 151; May be involved in acrosome formation of spermatids.	E3 ubiquitin-protein ligase RNF126; E3 ubiquitin-protein ligase that mediates ubiquitination oF target proteins. Depending on the associated E2 ligase, mediates 'Lys-48'- and 'Lys-63'- linked polyubiquitination of substrates (By similarity). Part of a BAG6-dependent quality control process ensuring that proteins of the secretory pathway that are mislocalized to the cytosol are degraded by the proteasome. Probably acts by providing the ubiquitin ligase activity associated with the BAG6 complex and be responsible for ubiquitination of the hydrophobic mislocalized proteins and their targe [...]	0.529
RNF151	RNF133	ENSP00000456566	ENSP00000344489	RING finger protein 151; May be involved in acrosome formation of spermatids.	E3 ubiquitin-protein ligase RNF133; Has E3 ubiquitin-protein ligase activity.	0.556
RNF151	RNF175	ENSP00000456566	ENSP00000340979	RING finger protein 151; May be involved in acrosome formation of spermatids.	Ring finger protein 175.	0.489
RNF151	SH2D7	ENSP00000456566	ENSP00000327846	RING finger protein 151; May be involved in acrosome formation of spermatids.	SH2 domain containing 7.	0.474
RNF151	UBE2D2	ENSP00000456566	ENSP00000381717	RING finger protein 151; May be involved in acrosome formation of spermatids.	Ubiquitin-conjugating enzyme E2 D2; Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'- linked polyubiquitination. Mediates the selective degradation of short- lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and autoubiquitination of STUB1 and TRAF6. Involved in the signal-induced conjugation and subsequent degradation of NFKBIA, FBXW2-mediated GCM1 ubiquitination and degradation, MDM2-dependent degradation of p53/TP53 and the activation of [...]	0.479
RNF175	RNF151	ENSP00000340979	ENSP00000456566	Ring finger protein 175.	RING finger protein 151; May be involved in acrosome formation of spermatids.	0.489
SH2D7	RNF151	ENSP00000327846	ENSP00000456566	SH2 domain containing 7.	RING finger protein 151; May be involved in acrosome formation of spermatids.	0.474