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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TBC1D3GTBC1 domain family member 3G; Acts as a GTPase activating protein for RAB5. Does not act on RAB4 or RAB11 (By similarity). (549 aa)    
Predicted Functional Partners:
CDRT15L2
CMT1A duplicated region transcript 15 like 2.
      
 0.580
NPIPA3
Nuclear pore complex interacting protein family member A3.
    
 
 0.548
OR4X2
Olfactory receptor 4X2; Odorant receptor.
      
 0.507
CT45A7
Cancer/testis antigen family 45 member A7.
      
 0.480
CCDC144A
Coiled-coil domain containing 144A.
      
 0.479
SLC35G3
Solute carrier family 35 member G3.
      
 0.476
ZNF670
Zinc finger protein 670; May be involved in transcriptional regulation.
    
 
 0.476
SLC35G6
Solute carrier family 35 member G6.
      
 0.476
C17orf64
Uncharacterized protein C17orf64; Chromosome 17 open reading frame 64.
      
 0.447
SPDYE4
Speedy protein E4; speedy/RINGO cell cycle regulator family member E4; Belongs to the Speedy/Ringo family.
      
 0.447
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.