HSPB9 protein (human) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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[Homology]

Score

HSPB9

Heat shock protein family B member 9. (159 aa)

Predicted Functional Partners:

ITFG2

0.940

PARS2

0.800

HSPB8

0.763

HSPB7

0.760

ODF1

0.749

NCKAP1

0.728

CYFIP2

0.709

HSPB2

0.669

CRYAA

0.668

HSPB6

0.665

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CRYAA	HSPB2	ENSP00000291554	ENSP00000302476	Alpha-crystallin A2(1-162); Contributes to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. Belongs to the small heat shock protein (HSP20) family.	Heat shock protein beta-2; May regulate the kinase DMPK.	0.529
CRYAA	HSPB7	ENSP00000291554	ENSP00000364870	Alpha-crystallin A2(1-162); Contributes to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. Belongs to the small heat shock protein (HSP20) family.	Heat shock protein family B member 7; Belongs to the small heat shock protein (HSP20) family.	0.650
CRYAA	HSPB9	ENSP00000291554	ENSP00000458018	Alpha-crystallin A2(1-162); Contributes to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. Belongs to the small heat shock protein (HSP20) family.	Heat shock protein family B member 9.	0.668
CRYAA	ODF1	ENSP00000291554	ENSP00000285402	Alpha-crystallin A2(1-162); Contributes to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. Belongs to the small heat shock protein (HSP20) family.	Outer dense fiber protein 1; Component of the outer dense fibers (ODF) of spermatozoa. ODF are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail.	0.594
CYFIP2	HSPB9	ENSP00000479719	ENSP00000458018	Cytoplasmic FMR1-interacting protein 2; Involved in T-cell adhesion and p53/TP53-dependent induction of apoptosis. Does not bind RNA. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (By similarity).	Heat shock protein family B member 9.	0.709
CYFIP2	NCKAP1	ENSP00000479719	ENSP00000354251	Cytoplasmic FMR1-interacting protein 2; Involved in T-cell adhesion and p53/TP53-dependent induction of apoptosis. Does not bind RNA. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (By similarity).	Nck-associated protein 1; Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Actin remodeling activity is regulated by RAC1. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes.	0.999
HSPB2	CRYAA	ENSP00000302476	ENSP00000291554	Heat shock protein beta-2; May regulate the kinase DMPK.	Alpha-crystallin A2(1-162); Contributes to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. Belongs to the small heat shock protein (HSP20) family.	0.529
HSPB2	HSPB7	ENSP00000302476	ENSP00000364870	Heat shock protein beta-2; May regulate the kinase DMPK.	Heat shock protein family B member 7; Belongs to the small heat shock protein (HSP20) family.	0.661
HSPB2	HSPB8	ENSP00000302476	ENSP00000281938	Heat shock protein beta-2; May regulate the kinase DMPK.	Heat shock protein beta-8; Displays temperature-dependent chaperone activity; Belongs to the small heat shock protein (HSP20) family.	0.865
HSPB2	HSPB9	ENSP00000302476	ENSP00000458018	Heat shock protein beta-2; May regulate the kinase DMPK.	Heat shock protein family B member 9.	0.669
HSPB2	ODF1	ENSP00000302476	ENSP00000285402	Heat shock protein beta-2; May regulate the kinase DMPK.	Outer dense fiber protein 1; Component of the outer dense fibers (ODF) of spermatozoa. ODF are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail.	0.434
HSPB6	HSPB7	ENSP00000004982	ENSP00000364870	Heat shock protein beta-6; Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding- competent state. Seems to have versatile functions in various biological processes. Plays a role in regulating muscle function such as smooth muscle vasorelaxation and cardiac myocyte contractility. May regulate myocardial angiogenesis implicating KDR. Overexpression mediates cardioprotection and angiogenesis after induced damage. Stabilizes monomeric YWHAZ thereby supporting YWHAZ chaperone-like activity.	Heat shock protein family B member 7; Belongs to the small heat shock protein (HSP20) family.	0.663
HSPB6	HSPB8	ENSP00000004982	ENSP00000281938	Heat shock protein beta-6; Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding- competent state. Seems to have versatile functions in various biological processes. Plays a role in regulating muscle function such as smooth muscle vasorelaxation and cardiac myocyte contractility. May regulate myocardial angiogenesis implicating KDR. Overexpression mediates cardioprotection and angiogenesis after induced damage. Stabilizes monomeric YWHAZ thereby supporting YWHAZ chaperone-like activity.	Heat shock protein beta-8; Displays temperature-dependent chaperone activity; Belongs to the small heat shock protein (HSP20) family.	0.800
HSPB6	HSPB9	ENSP00000004982	ENSP00000458018	Heat shock protein beta-6; Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding- competent state. Seems to have versatile functions in various biological processes. Plays a role in regulating muscle function such as smooth muscle vasorelaxation and cardiac myocyte contractility. May regulate myocardial angiogenesis implicating KDR. Overexpression mediates cardioprotection and angiogenesis after induced damage. Stabilizes monomeric YWHAZ thereby supporting YWHAZ chaperone-like activity.	Heat shock protein family B member 9.	0.665
HSPB6	ODF1	ENSP00000004982	ENSP00000285402	Heat shock protein beta-6; Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding- competent state. Seems to have versatile functions in various biological processes. Plays a role in regulating muscle function such as smooth muscle vasorelaxation and cardiac myocyte contractility. May regulate myocardial angiogenesis implicating KDR. Overexpression mediates cardioprotection and angiogenesis after induced damage. Stabilizes monomeric YWHAZ thereby supporting YWHAZ chaperone-like activity.	Outer dense fiber protein 1; Component of the outer dense fibers (ODF) of spermatozoa. ODF are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail.	0.547
HSPB7	CRYAA	ENSP00000364870	ENSP00000291554	Heat shock protein family B member 7; Belongs to the small heat shock protein (HSP20) family.	Alpha-crystallin A2(1-162); Contributes to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. Belongs to the small heat shock protein (HSP20) family.	0.650
HSPB7	HSPB2	ENSP00000364870	ENSP00000302476	Heat shock protein family B member 7; Belongs to the small heat shock protein (HSP20) family.	Heat shock protein beta-2; May regulate the kinase DMPK.	0.661
HSPB7	HSPB6	ENSP00000364870	ENSP00000004982	Heat shock protein family B member 7; Belongs to the small heat shock protein (HSP20) family.	Heat shock protein beta-6; Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding- competent state. Seems to have versatile functions in various biological processes. Plays a role in regulating muscle function such as smooth muscle vasorelaxation and cardiac myocyte contractility. May regulate myocardial angiogenesis implicating KDR. Overexpression mediates cardioprotection and angiogenesis after induced damage. Stabilizes monomeric YWHAZ thereby supporting YWHAZ chaperone-like activity.	0.663
HSPB7	HSPB8	ENSP00000364870	ENSP00000281938	Heat shock protein family B member 7; Belongs to the small heat shock protein (HSP20) family.	Heat shock protein beta-8; Displays temperature-dependent chaperone activity; Belongs to the small heat shock protein (HSP20) family.	0.988
HSPB7	HSPB9	ENSP00000364870	ENSP00000458018	Heat shock protein family B member 7; Belongs to the small heat shock protein (HSP20) family.	Heat shock protein family B member 9.	0.760